Implementation and validation of the thermogravimetric method for the determination of equilibrium vapour pressure values and sublimation enthalpies of frozen organic formulations used in drug freeze-drying processes

Chemical Engineering Research and Design

Volumn 89, Issue 12, 2011, Pages 2606-2612

  Bogdani, Eni ^a   Daoussi, Rim ^a   Vessot, Séverine ^a   Jose, Jacques ^a   Andrieu, Julien ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Freeze drying; Sublimation enthalpies; Sublimation vapour pressure; Tert butanol; Thermogravimetry

Indexed keywords

COMPARATIVE METHODS; COSOLVENTS; DYNAMIC CONDITION; EQUILIBRIUM PRESSURE; EQUILIBRIUM VALUE; EUTECTIC MIXTURE; FREEZE-DRYING; FREEZE-DRYING PROCESS; LIQUID-VAPOUR EQUILIBRIA; PURE SUBSTANCES; RELATIVE DEVIATIONS; STATIC METHOD; SUBLIMATION ENTHALPIES; SUBLIMATION ENTHALPY; TEMPERATURE RANGE; TERT BUTANOL; THERMOGRAVIMETRIC METHOD; VAPOUR PRESSURES; WATER MIXTURE;

ALCOHOLS; DRYING; ENTHALPY; LOW TEMPERATURE DRYING; METAL CLADDING; MIXTURES; PHASE TRANSITIONS; SOLVENTS; THERMOGRAVIMETRIC ANALYSIS; VAPOR PRESSURE;

SUBLIMATION;

EID: 80054008557     PISSN: 02638762     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cherd.2011.05.004     Document Type: Article

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