-
1
-
-
84856765633
-
-
Product information. Sunitinib malate (Sutent), (accessed 2010 Jul)
-
Product information. Sunitinib malate (Sutent). http://www.pfizer.com/files/products/uspi_sutent.pdf (accessed 2010 Jul).
-
-
-
-
2
-
-
78650874372
-
SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
-
Abrams TJ, Lee LB, Murray LJ, Pryer NK, Cherrington JM. SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer. Mol Cancer Ther 2003;2:471-8.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 471-478
-
-
Abrams, T.J.1
Lee, L.B.2
Murray, L.J.3
Pryer, N.K.4
Cherrington, J.M.5
-
3
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/ pharmacodynamic relationship
-
Mendel DB, Laird AD, Xin X, et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/ pharmacodynamic relationship. Clin Cancer Res 2003;9:327-37.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
-
4
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
O'Farrell AM, Abrams TJ, Yuen HA, et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003;101:3597-605.
-
(2003)
Blood
, vol.101
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
-
5
-
-
33749544080
-
An orally administered multi-target tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases
-
DOI 10.1210/jc.2005-2845
-
Kim DW, Jo YS, Jung HS, et al. An orally administered multi-target tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases. J Clin Endocrinol Metab 2006;91:4070-6. DOI 10.1210/jc.2005-2845
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 4070-4076
-
-
Kim, D.W.1
Jo, Y.S.2
Jung, H.S.3
-
6
-
-
77349124902
-
Targeted therapy for gastrointestinal stromal tumors: Current status and future perspectives
-
DOI 10.1007/s10555010-9206-7
-
Papaetis GS, Syrigos KN. Targeted therapy for gastrointestinal stromal tumors: current status and future perspectives. Cancer Metastasis Rev 2010;29:151-70. DOI 10.1007/s10555010-9206-7
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 151-170
-
-
Papaetis, G.S.1
Syrigos, K.N.2
-
7
-
-
34548596943
-
Hyperammonemia encephalopathy: An important cause of neurological deterioration following chemotherapy
-
DOI 10.1080/10428190701509822
-
Nott L, Price TJ, Pittman K, Patterson K, Fletcher J. Hyperammonemia encephalopathy: an important cause of neurological deterioration following chemotherapy. Leuk Lymphoma 2007;48:1702-11. DOI 10.1080/10428190701509822
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 1702-1711
-
-
Nott, L.1
Price, T.J.2
Pittman, K.3
Patterson, K.4
Fletcher, J.5
-
8
-
-
78650796192
-
Clinical efficacy and safety of sunitinib after imatinib failure in Japanese patients with gastrointestinal stromal tumor
-
DOI 10.1093/jjco/hyq164
-
Matsumoto K, Sawaki A, Mizuno N, et al. Clinical efficacy and safety of sunitinib after imatinib failure in Japanese patients with gastrointestinal stromal tumor. Jpn J Clin Oncol 2011;41:57-62. DOI 10.1093/jjco/hyq164
-
(2011)
Jpn J Clin Oncol
, vol.41
, pp. 57-62
-
-
Matsumoto, K.1
Sawaki, A.2
Mizuno, N.3
-
9
-
-
0032796813
-
Risk of transient hyperammonemic encephalopathy in cancer patients who received continuous infusion 5-fluorouracil with the complication of dehydration and infection
-
Liaw CC, Wang HM, Wang CH, et al. Risk of transient hyperammonemic encephalopathy in cancer patients who received continuous infusion 5-fluorouracil with the complication of dehydration and infection. Anticancer Drugs 1999;10:275-81.
-
(1999)
Anticancer Drugs
, vol.10
, pp. 275-281
-
-
Liaw, C.C.1
Wang, H.M.2
Wang, C.H.3
-
10
-
-
0030037746
-
Idiopathic hyperammonemia: A frequently lethal complication of bone marrow transplantation
-
Davies SM, Szabo E, Wagner JE, Ramsay NK, Weisdorf DJ. Idiopathic hyperammonemia: a frequently lethal complication of bone marrow transplantation. Bone Marrow Transplant 1996;17:1119-25.
-
(1996)
Bone Marrow Transplant
, vol.17
, pp. 1119-1125
-
-
Davies, S.M.1
Szabo, E.2
Wagner, J.E.3
Ramsay, N.K.4
Weisdorf, D.J.5
-
11
-
-
77949535841
-
Pharmacological management of gastrointestinal stromal tumours: An update on the role of sunitinib
-
DOI 10.1093/annonc/mdp291
-
Blay JY. Pharmacological management of gastrointestinal stromal tumours: an update on the role of sunitinib. Ann Oncol 2010;21:208-15. DOI 10.1093/annonc/mdp291
-
(2010)
Ann Oncol
, vol.21
, pp. 208-215
-
-
Blay, J.Y.1
-
12
-
-
77952310126
-
Risk of arterial thromboembolic events with sunitinib and sorafenib: A systematic review and meta-analysis of clinical trials
-
DOI 10.1200/JCO.2009.27.2757
-
Choueiri TK, Schutz FA, Je Y, Rosenberg JE, Bellmunt J. Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. J Clin Oncol 2010;28:2280-5. DOI 10.1200/JCO.2009.27.2757
-
(2010)
J Clin Oncol
, vol.28
, pp. 2280-2285
-
-
Choueiri, T.K.1
Schutz, F.A.2
Je, Y.3
Rosenberg, J.E.4
Bellmunt, J.5
-
13
-
-
61449110041
-
Acute hepatic failure following monotherapy with sunitinib for ovarian cancer
-
DOI 10.1007/s00280-008-0814-7
-
Taran A, Ignatov A, Smith B, Costa SD, Bischoff J. Acute hepatic failure following monotherapy with sunitinib for ovarian cancer. Cancer Chemother Pharmacol 2009;63:971-2. DOI 10.1007/s00280-008-0814-7
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 971-972
-
-
Taran, A.1
Ignatov, A.2
Smith, B.3
Costa, S.D.4
Bischoff, J.5
-
14
-
-
48249088860
-
Sunitinib-related fulminant hepatic failure: Case report and review of the literature
-
DOI 10.1592/phco.28.8.1066
-
Mueller EW, Rockey ML, Rashkin MC. Sunitinib-related fulminant hepatic failure: case report and review of the literature. Pharmacotherapy 2008;28:1066-70. DOI 10.1592/phco.28.8.1066
-
(2008)
Pharmacotherapy
, vol.28
, pp. 1066-1070
-
-
Mueller, E.W.1
Rockey, M.L.2
Rashkin, M.C.3
-
15
-
-
45949111118
-
Posterior reversible encephalopathy syndrome during sunitinib therapy
-
DOI 10.1016/j.neurol.2008.03.007
-
Cumurciuc R, Martinez-Almoyna L, Henry C, Husson H, de Broucker T. Posterior reversible encephalopathy syndrome during sunitinib therapy. Rev Neurol 2008;164:605-7 DOI 10.1016/j.neurol.2008.03.007
-
(2008)
Rev Neurol
, vol.164
, pp. 605-617
-
-
Cumurciuc, R.1
Martinez-Almoyna, L.2
Henry, C.3
Husson, H.4
de Broucker, T.5
-
16
-
-
0019799332
-
A method for estimating the probability of adverse drug reactions
-
Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.
-
(1981)
Clin Pharmacol Ther
, vol.30
, pp. 239-245
-
-
Naranjo, C.A.1
Busto, U.2
Sellers, E.M.3
-
17
-
-
72249095151
-
Sorafenib-induced hepatic encephalopathy
-
DOI 10.1345/aph.1M457
-
Marks A-B, Gerard R, Fournier P, Coupe P, Gautier S. Sorafenib-induced hepatic encephalopathy. Ann Pharmacother 2009;43:2121. DOI 10.1345/aph.1M457
-
(2121)
Ann Pharmacother
, vol.2009
, pp. 43
-
-
Marks, A.-B.1
Gerard, R.2
Fournier, P.3
Coupe, P.4
Gautier, S.5
-
18
-
-
77953033291
-
Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: Results of a pharmacokinetic/pharmacodynamic meta-analysis
-
DOI 10.1007/s00280-009-1170-y
-
Houk BE, Bello CL, Poland B, Rosen LS, Demetri GD, Motzer RJ. Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis. Cancer Chemother Pharmacol 2010;66:357-71. DOI 10.1007/s00280-009-1170-y
-
(2010)
Cancer Chemother Pharmacol
, vol.66
, pp. 357-371
-
-
Houk, B.E.1
Bello, C.L.2
Poland, B.3
Rosen, L.S.4
Demetri, G.D.5
Motzer, R.J.6
-
19
-
-
60549098640
-
Sorafenib: A review of its use in advanced hepatocellular carcinoma
-
DOI 10.2165/00003495-200969020-00006
-
Keating GM, Santoro A. Sorafenib: a review of its use in advanced hepatocellular carcinoma. Drugs 2009;69:223-40. DOI 10.2165/00003495-200969020-00006
-
(2009)
Drugs
, vol.69
, pp. 223-240
-
-
Keating, G.M.1
Santoro, A.2
-
20
-
-
70449704111
-
Clinical pharmacokinetics of tyrosine kinase inhibitors
-
DOI 10.1016/j.ctrv.2009.08.004
-
van Erp NP, Gelderblom H, Guchelaar HJ. Clinical pharmacokinetics of tyrosine kinase inhibitors. Cancer Treat Rev 2009;35:692-706. DOI 10.1016/j.ctrv.2009.08.004
-
(2009)
Cancer Treat Rev
, vol.35
, pp. 692-706
-
-
van Erp, N.P.1
Gelderblom, H.2
Guchelaar, H.J.3
-
21
-
-
35348850012
-
Valproate-associated hyperammonemic encephalopathy
-
DOI 10.3122/jabfm.2007.05.070062
-
Wadzinski J, Franks R, Roane D, Bayard M. Valproate-associated hyperammonemic encephalopathy. J Am Board Fam Med 2007;20:499-502. DOI 10.3122/jabfm.2007.05.070062
-
(2007)
J Am Board Fam Med
, vol.20
, pp. 499-502
-
-
Wadzinski, J.1
Franks, R.2
Roane, D.3
Bayard, M.4
-
22
-
-
69249202553
-
Ammonia toxicity and its prevention in inherited defects of the urea cycle
-
DOI 10.1111/j.1463-1326.2009.01054.x
-
Walker V. Ammonia toxicity and its prevention in inherited defects of the urea cycle. Diabetes Obes Metab 2009;11:823-35. DOI 10.1111/j.1463-1326.2009.01054.x
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 823-835
-
-
Walker, V.1
-
23
-
-
77954996173
-
The efficacy and safety of sunitinib in Korean patients with advanced renal cell carcinoma: High incidence of toxicity leads to frequent dose reduction
-
DOI 10.1093/jjco/hyq073
-
Yoo C, Kim JE, Lee JL, et al. The efficacy and safety of sunitinib in Korean patients with advanced renal cell carcinoma: high incidence of toxicity leads to frequent dose reduction. Jpn J Clin Oncol 2010;40:980-5. DOI 10.1093/jjco/hyq073
-
(2010)
Jpn J Clin Oncol
, vol.40
, pp. 980-985
-
-
Yoo, C.1
Kim, J.E.2
Lee, J.L.3
-
24
-
-
77950348305
-
A phase II study of sunitinib in Japanese patients with metastatic renal cell carcinoma: Insights into the treatment, efficacy and safety
-
DOI 10.1093/jjco/hyq146
-
Uemura H, Shinohara N, Yuasa T, et al. A phase II study of sunitinib in Japanese patients with metastatic renal cell carcinoma: insights into the treatment, efficacy and safety. Jpn J Clin Oncol 2010;40:194-202. DOI 10.1093/jjco/hyq146
-
(2010)
Jpn J Clin Oncol
, vol.40
, pp. 194-202
-
-
Uemura, H.1
Shinohara, N.2
Yuasa, T.3
-
25
-
-
68249135542
-
UGT1A1 polymorphism and hyperbilirubinemia in a patient who received sorafenib
-
DOI 10.1007/s00280-009-1096-4
-
Meza-Junco J, Chu QS, Christensen O, et al. UGT1A1 polymorphism and hyperbilirubinemia in a patient who received sorafenib. Cancer Chemother Pharmacol 2009;65:1-4. DOI 10.1007/s00280-009-1096-4
-
(2009)
Cancer Chemother Pharmacol
, vol.65
, pp. 1-4
-
-
Meza-Junco, J.1
Chu, Q.S.2
Christensen, O.3
|