The NADPH oxidase cytosolic component p67phox is constitutively phosphorylated in human neutrophils: Regulation by a protein tyrosine kinase, MEK1/2 and phosphatases 1/2A

Biochemical Pharmacology

Volumn 82, Issue 9, 2011, Pages 1145-1152

  Dang, Pham My Chan ^a,b   Raad, Houssam ^a,b   Derkawi, Riad Arabi ^a,b   Boussetta, Tarek ^a,b   Paclet, Marie Hélne ^d   Belambri, Sahra Amel ^a,b   Makni Maalej, Karama ^a,b   Kroviarski, Yolande ^a,c   Morel, Franoise ^d   Gougerot Pocidalo, Marie Anne ^a,c   El Benna, Jamel ^a,b  

^a CENTRE DE RECHERCHE BIOMÉDICALE BICHAT BEAUJON CRB3   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c BICHAT HOSPITAL   (France)

^d GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

Inflammation; NADPH oxidase; Neutrophils; p67phox; Phosphorylation; ROS

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALYCULIN A; GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE C INHIBITOR; PROTEIN P67PHOX; PROTEIN TYROSINE KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NEUTROPHIL; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION;

CELLS, CULTURED; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NADPH OXIDASE; NEUTROPHILS; OXAZOLES; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2;

EID: 80053968646     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.07.070     Document Type: Article

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