A variant OSR1 allele which disturbs OSR1 mRNA expression in renal progenitor cells is associated with reduction of newborn kidney size and function

Human Molecular Genetics

Volumn 20, Issue 21, 2011, Pages 4167-4174

  Zhang, Zhao ^a   Iglesias, Diana ^a   Eliopoulos, Nicoletta ^b   Kares, Reyhan El ^a   Chu, LeeLee ^a   Romagnani, Paola ^c   Goodyer, Paul ^a,b  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CD24 ANTIGEN; CYSTATIN C; MESSENGER RNA;

ALLELE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BLASTEMA; CAUCASIAN; CONTROLLED STUDY; EMBRYO; ENHANCER REGION; EXON; GENE; GENE EXPRESSION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INFANT; KIDNEY FUNCTION; KIDNEY SIZE; MESENCHYMAL STEM CELL; MOUSE; NEPHROBLASTOMA; NEPHRON; NEWBORN; NONHUMAN; NORMAL HUMAN; OSR1 GENE; PAX2 GENE; PRIORITY JOURNAL; RENAL PROGENITOR CELL; RET GENE; RNA STABILITY; SPLICEOSOME; STEM CELL; UMBILICAL CORD BLOOD; WILD TYPE;

ADULT; ALLELES; ANIMALS; ANIMALS, NEWBORN; BASE SEQUENCE; CELL SEPARATION; CYSTATIN C; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HETEROZYGOTE; HUMANS; IN SITU HYBRIDIZATION; INFANT, NEWBORN; KIDNEY; MESENCHYMAL STEM CELLS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; ORGAN SIZE; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; TRANSCRIPTION FACTORS; UMBILICAL CORD; WILMS TUMOR;

EID: 80053963629     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr341     Document Type: Article

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