Microfluidic devices for analysis of spatial orientation behaviors in semi-restrained Caenorhabditis elegans

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  McCormick, Kathryn E ^a   Gaertner, Bryn E ^a   Sottile, Matthew ^b   Phillips, Patrick C ^a   Lockery, Shawn R ^a  

^a UNIVERSITY OF OREGON   (United States)

^b Galois Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL BEHAVIOR; ARTICLE; AVOIDANCE BEHAVIOR; CAENORHABDITIS ELEGANS; CHEMOTAXIS; CONTROLLED STUDY; HEAD; MICROFLUIDIC ANALYSIS; NONHUMAN; OSMOLARITY; SENSORY STIMULATION; SPATIAL ORIENTATION; TAIL; TIME PERCEPTION; ANIMAL; BEHAVIOR; DRUG EFFECT; EXERCISE; METHODOLOGY; ORIENTATION; PHYSIOLOGY; TEMPERATURE; TIME;

ANIMALIA; CAENORHABDITIS ELEGANS; NEMATODA;

CHEMOTACTIC FACTOR;

ANIMALS; BEHAVIOR, ANIMAL; CAENORHABDITIS ELEGANS; CHEMOTACTIC FACTORS; MICROFLUIDIC ANALYTICAL TECHNIQUES; ORIENTATION; OSMOLAR CONCENTRATION; RESTRAINT, PHYSICAL; SPATIAL BEHAVIOR; TEMPERATURE; TIME FACTORS;

EID: 80053962866     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025710     Document Type: Article

References (43)

1. Adler J, (1966) Chemotaxis in bacteria. Science 153: 708-716.
2. Porter J, Craven B, Khan RM, Chang SJ, Kang I, et al. (2007) Mechanisms of scent-tracking in humans. Nat Neurosci 10: 27-29.
3. Jeon NL, Dertinger SKW, Chiu DT, Choi IS, Stroock AD, et al. (2000) Generation of solution and surface gradients using microfluidic systems. Langmuir 16: 8311-8316.
4. Ahmed T, Shimizu TS, Stocker R, (2010) Microfluidics for bacterial chemotaxis. Integr Biol (Camb) 2: 604-629.
5. Giuffre C, Hinow P, Vogel R, Ahmed T, Stocker R, et al. (2011) The ciliate Paramecium shows higher motility in non-uniform chemical landscapes. PLoS ONE 6: e15274.
6. Koyama S, Amarie D, Soini HA, Novotny MV, Jacobson SC, (2006) Chemotaxis assays of mouse sperm on microfluidic devices. Anal Chem 78: 3354-3359.
7. Lockery SR, Lawton KJ, Doll JC, Faumont S, Coulthard SM, et al. (2008) Artificial dirt: microfluidic substrates for nematode neurobiology and behavior. J Neurophysiol 99: 3136-3143.
8. Albrecht DR, Bargmann CI, (2011) High-content behavioral analysis of Caenorhabditis elegans in precise spatiotemporal chemical environments. Nat Methods.
9. Riddle DL, Blumenthal T, Meyer BJ, Priess JR, (1997) C. elegans II Plainview Cold Spring Harbor Laboratory Press.
10. Ben-Yakar A, Chronis N, Lu H, (2009) Microfluidics for the analysis of behavior, nerve regeneration, and neural cell biology in C. elegans. Curr Opin Neurobiol 19: 561-567.
11. Bargmann CI, (2006) Chemosensation in C. elegans. pp. 1-29 WormBook.
12. Garrity PA, Goodman MB, Samuel AD, Sengupta P, (2010) Running hot and cold: behavioral strategies, neural circuits, and the molecular machinery for thermotaxis in C. elegans and Drosophila. Genes Dev 24: 2365-2382.
13. Culotti J, Russell R, (1978) Osmotic avoidance defective mutants of the nematode C. elegans. Genetics 90: 243-256.
14. Pierce-Shimomura JT, Morse TM, Lockery SR, (1999) The fundamental role of pirouettes in Caenorhabditis elegans chemotaxis. J Neurosci 19: 9557-9569.
15. Iino Y, Yoshida K, (2009) Parallel use of two behavioral mechanisms for chemotaxis in Caenorhabditis elegans. J Neurosci 29: 5370-5380.
16. Fraenkel GS, Gunn DL, (1940) The Orientation of Animals Oxford Oxford University Press.
17. Lockery SR, (2011) The computational worm: spatial orientation and its neuronal basis in C. elegans. Curr Opin Neurobiol (in press).
18. Pierce-Shimomura JT, Chen BL, Mun JJ, Ho R, Sarkis R, et al. (2008) Genetic analysis of crawling and swimming locomotory patterns in C. elegans. Proc Natl Acad Sci U S A 105: 20982-20987.
19. Dusenbery DB, Sheridan RE, Russell RL, (1975) Chemotaxis-defective mutants of the nematode Caenorhabditis elegans. Genetics 80: 297-309.
20. Komatsu J, Mori I, Rhee J-S, Akaike N, Ohshima Y, (1996) Mutations in a cyclic neucleotide-gated channel lead to abnormal thermosensation and chemosesnation in C. elegans. Neuron 17: 707-718.
21. Hilliard MA, Bargmann CI, Bazzicalupo P, (2002) C. elegans responds to chemical repellents by integrating sensory inputs from the head and the tail. Curr Biol 12: 730-734.
22. Chokshi TV, Bazopoulou D, Chronis N, (2010) An automated microfluidic platform for calcium imaging of chemosensory neurons in Caenorhabditis elegans. Lab Chip 10: 2758-2763.
23. Ryu WS, Samuel AD, (2002) Thermotaxis in Caenorhabditis elegans analyzed by measuring responses to defined thermal stimuli. J Neurosci 22: 5727-5733.
24. Zariwala HA, Miller AC, Faumont S, Lockery SR, (2003) Step response analysis of thermotaxis in Caenorhabditis elegans. J Neurosci 23: 4369-4377.
25. Hedgecock EM, Russell RL, (1975) Normal and mutant thermotaxis in the nematode Caenorhabditis elegans. Proceedings of the National Academy of Science 72: 4061-4065.
26. Ramot D, MacInnis BL, Lee HC, Goodman MB, (2008) Thermotaxis is a robust mechanism for thermoregulation in Caenorhabditis elegans nematodes. J Neurosci 28: 12546-12557.
27. Jurado P, Kodama E, Tanizawa Y, Mori I, (2010) Distinct thermal migration behaviors in response to different thermal gradients in Caenorhabditis elegans. Genes Brain Behav 9: 120-127.
28. Ito H, Inada H, Mori I, (2006) Quantitative analysis of thermotaxis in the nematode Caenorhabditis elegans. J Neurosci Methods 154: 45-52.
29. Wicks SR, de Vries CJ, van Luenen HG, Plasterk RH, (2000) CHE-3, a cytosolic dynein heavy chain, is required for sensory cilia structure and function in Caenorhabditis elegans. Dev Biol 221: 295-307.
30. Ward S, (1973) Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants and analysis of the response by use of mutants. Proc Natl Acad Sci U S A 70: 817-821.
31. Bargmann CI, Horvitz HR, (1991) Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegans. Neuron 7: 729-742.
32. White JQ, Nicholas TJ, Gritton J, Truong L, Davidson ER, et al. (2007) The sensory circuitry for sexual attraction in C. elegans males. Curr Biol 17: 1847-1857.
33. Gray JM, Karow DS, Lu H, Chang AJ, Chang JS, et al. (2004) Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature 430: 317-322.
34. Bretscher AJ, Kodama-Namba E, Busch KE, Murphy RJ, Soltesz Z, et al. (2011) Temperature, Oxygen, and Salt-Sensing Neurons in C. elegans Are Carbon Dioxide Sensors that Control Avoidance Behavior. Neuron 69: 1099-1113.
35. Sambongi Y, Nagae T, Liu Y, Yoshimizu T, Takeda K, et al. (1999) Sensing of cadmium and copper ions by externally exposed ADL, ASE, and ASH neurons elicits avoidance response in Caenorhabditis elegans. Neuroreport 10: 753-757.
36. Ardiel EL, Rankin CH, (2010) An elegant mind: learning and memory in Caenorhabditis elegans. Learn Mem 17: 191-201.
37. Izquierdo EJ, Lockery SR, (2010) Evolution and Analysis of Minimal Neural Circuits for Klinotaxis in Caenorhabditis elegans. J Neurosci 30: 12908-12917.
38. Faumont S, Lockery SR, (2006) The awake behaving worm: simultaneous imaging of neuronal activity and behavior in intact animals at millimeter scale. J Neurophysiol 95: 1976-1981.
39. Stirman JN, Crane MM, Husson SJ, Wabnig S, Schultheis C, et al. (2011) Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans. Nat Methods 8: 153-158.
40. Leifer AM, Fang-Yen C, Gershow M, Alkema MJ, Samuel AD, (2011) Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans. Nat Methods 8: 147-152.
41. Qin D, Xia Y, Whitesides GM, (2010) Soft lithography for micro- and nanoscale patterning. Nat Protoc 5: 491-502.
42. Stiernagle T, (2006) Maintenance of C. elegans. pp. 1-11 WormBook.
43. Faumont S, Miller AC, Lockery SR, (2005) Chemosensory behavior of semi-restrained Caenorhabditis elegans. J Neurobiol 65: 171-178.