Differential proteomic analysis of highly purified placental cytotrophoblasts in pre-eclampsia demonstrates a state of increased oxidative stress and reduced cytotrophoblast antioxidant defense

Proteomics

Volumn 11, Issue 20, 2011, Pages 4077-4084

  Johnstone, Edward D ^a   Sawicki, Grzgorz ^b,c   Guilbert, Larry ^d   Winkler Lowen, Bonnie ^d   Cadete, Virgilio J J ^b   Morrish, Donald W ^d  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c WROCLAW MEDICAL UNIVERSITY   (Poland)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cell biology; Cytotrophoblast; Placenta; Pre eclampsia

Indexed keywords

ACTIN; ALDEHYDE REDUCTASE; BETA TUBULIN; EZRIN; FETUIN; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; PEROXIREDOXIN 6; PHOSPHOGLYCERATE MUTASE; PROTEASOME; PROTEIN DISULFIDE ISOMERASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL ARTICLE; CYTOTROPHOBLAST; FEMALE; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PLACENTA; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS;

BLOTTING, WESTERN; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; FETUINS; HUMANS; OXIDATIVE STRESS; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; PROTEOMICS; TROPHOBLASTS; UP-REGULATION;

EID: 80053957900     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201000505     Document Type: Article

References (52)

1. Cunningham, F. G., Lindheimer, M. D., Hypertension in pregnancy. N. Engl. J. Med. 1992, 326, 927-932.
2. Sibai, B., Dekker, G., Kupferminc, M., Pre-eclampsia Lancet 2005, 365, 785-799.
3. Roberts, J. M., Lain, K. Y., Recent insights into the pathogenesis of pre-eclampsia. Placenta 2002, 23, 359-372.
4. Redman, C. W. G., Sargent, I. L., Placental debris, oxidative stress and pre-eclampsia. Placenta 2000, 21, 597-602.
5. Redman, C. W. G., Sacks, G. P., Sargent, I. L., Preeclampsia, an excessive maternal inflammatory response to pregnancy. Am. J. Obstet.Gynecol. 1999, 180, 499-506.
6. Watanabe, H., Hamada, H., Yamada, N., Sohda, S. et al., Proteome analysis reveals elevated serum levels of clusterin in patients with preeclampsia. Proteomics 2004, 4, 537-543.
7. Wang, C. C., Kim, C. W., Poon, T. C. W., Choy, K. W. et al., Innate immune response by ficolin binding in apoptotic placenta is associated with the clinical syndrome of preeclampsia. Clin. Chem. 2007, 53, 42-52.
8. Myers, J., MacLeod, M., Reed, B., Harris, N. et al., Use of proteomic patterns as a novel screening tool in pre-eclampsia. J. Obstet. Gynecol. 2004, 24, 873-874.
9. Auer, J., Camoin, L., Guillonneau, F., Chelbi, S. T. et al., Serum profile in preeclampsia and intra-uterine growth restriction revealed by iTRAQ technology. J. Proteomics 2010, 73, 1004-1017.
10. Blumenstein, M., Prakash, R., Cooper, G. J., North, R. A. et al., Aberrant processing of plasma vitronectin and high-molecular-weight kininogen precedes the onset of preeclampsia. Reprod. Sci. 2009, 16, 1144-1152.
11. Blumenstein, M., McMaster, M. T., Black, M. A., Wu, S. et al., A proteomic approach identifies early pregnancy biomarkers for preeclampsia: novel linkages between a predisposition to preeclampsia and cardiovascular disease. Proteomics 2009, 9, 2929-2945.
12. Buhimschi, C. S., Bhandari, V., Han, Y. W., Dulay, A. T. et al., Using proteomics in perinatal and neonatal sepsis: hopes and challenges for the future. Curr. Opin. Infect. Dis. 2009, 22, 235-243.
13. Buhimschi, C. S., Dulay, A. T., Abdel-Razeq, S., Zhao, G. et al., Fetal inflammatory response in women with proteomic biomarkers characteristic of intra-amniotic inflammation and preterm birth. BJOG 2009, 116, 257-267.
14. Mine, K., Katayama, A., Matsumura, T., Nishino, T. et al., Proteome analysis of human placentae. pre-eclampsia versus normal pregnancy. Placenta 2007, 28, 676-687.
15. Webster, R. P., Macha, S., Brockman, D., Myatt, L., Peroxynitrite treatment in vitro disables catalytic activity of recombinant p38 MAPK. Proteomics 2006, 6, 4838-4844.
16. Gharesi-Fard, B., Zolghadri, J., Kamali-Sarvestini, E., Proteome differences of placenta between pre-eclampsia and normal pregnancy. Placenta 2010, 31, 121-125.
17. Sun, L.-Z., Yang, N.-N., De, W., Xiao, Y.-S., Proteomic analysis of proteins differentially expressed in preeclamptic trophoblasts. Gynecol. Obstet. Invest. 2007, 64, 17-23.
18. Jin, H., Ma, K.-D., Hu, R., Chen, Y. et al., Analysis of expression and comparative profile of normal placental tissue proteins and those in preeclamptic patients using proteomic approaches. Anal. Chim. Acta 2008, 629, 158-164.
19. Guilbert, L. J., Winkler-Lowen, B., Placental alkaline phosphatase (PLAP) staining and human chorionic chorionic gonadotropin (hCG) production in cultures of fresh and cryopreserved cytotrophoblasts isolated by CD9/MHC class I/MHC class II immunoelimination. Placenta 2007, 28, 348-349.
20. Report of the National High Blood Pressure Education Program Working Group on high blood pressure in pregnancy. Am. J. Obstet. Gynecol. 2000, 183, S1-S22.
21. Sawicki, G., Dakour, J., Morrish, D. W., Functional proteomics of neurokinin B in the placenta indicates a novel role in regulating cytotrophoblast antioxidant defences. Proteomics 2003, 3, 2044-2051.
22. Wang, Y., Walsh, S. W., Kay, H. H., Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsia. Am. J. Obstet. Gynecol. 1992, 167, 945-949.
23. Wang, Y., Walsh, S. W., Antioxidant activities and mRNA expression of SOD, catalase, and glutathione peroxidase in normal and preeclamptic placentas. J. Soc. Gynecol. Invest. 1996, 3, 179-184.
24. Many, A., Hubel, C. A., Fisher, S. J., Roberts, J. M. et al., Invasive cytotrophoblasts manifest evidence of oxidative stress in preeclampsia. Am. J. Pathol. 2000, 156, 321-331.
25. Kossenjans, W., Eis, A., Shaay, R., Brockman, D. et al., Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia. Am. J. Physiol. 2000, 278, H1311-H1319.
26. Wang, Y., Walsh, S. W., Increased superoxide generation is associated with decreased superoxide dismutase activity and mRNA expression in placental trophoblast cells in pre-eclampsia. Placenta 2001, 22, 206-212.
27. Graham, C. H., Postovit, L. M., Park, H., Canning, M. T. et al., Adriana and Luisa Castelluci Award Lecture 1999: role of oxygen in the regulation of trophoblast gene expression and invasion. Placenta 2000, 21, 443-450.
28. Santoso, D. I. S., Rogers, P., Wallace, E. M., Manuelpillai, U. et al., Localization of indoleamine 2, 3-dioxygenase and 4-hydroxynonenal in normal and pre-eclamptic placentae. Placenta 2002, 23, 373-379.
29. Daiber, A., Redox signalling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species. Biochim. Biophys. Acta 2010, 1797, 897-906.
30. Rhee, S. G., Kang, S. W., Netto, L. E., Seo, M. S., A novel family of peroxidises, periredoxins. Biofactors 1999, 10, 207-209.
31. Ejima, K., Nanri, H., Toki, N., Kashimura, M. et al., Localization of thioredoxin reductase and thioredoxin in normal human placenta and their protective effect against oxidative stress. Placenta 1999, 20, 95-101.
32. Brodsky, J. L., Chiosis, G., Hsp70 molecular chaperones: emerging roles in human disease and identification of small molecular inhibitors. Curr. Topics Med. Chem. 2006, 6, 1215-1225.
33. Wieten, L., Broere, F., van der Zee, R., Koercamp, E. K. et al., Cell stress induced HSP are targets of regulatory T cells: a role for HSP inducing compounds as anti-inflammatory immuno-modulators? FEBS Lett. 2007, 581, 3702-3710.
34. Molvarec, A., Prohaszka, Z., Nagy, B., Szalay, J. et al., Association of elevated serum heat-shock protein 70 concentration with transient hypertension of pregnancy, preeclampsia and superimposed preeclampsia: a case-control study. J. Hum. Hypertension 2006, 20, 780-786.
35. Livingston, J. C., Ahokas, R., Haddad, B., Sibai, B. M. et al., Heat shock protein 70 is not increased in women with severe preeclampsia. Hypertens. Pregnancy 2002, 21, 123-126.
36. Straszewski-Chavez, S. L., Haddad, B., Mor, G., The role of apoptosis in the regulation of trophoblast survival and differentiation in pregnancy. Endocr. Rev. 2005 26, 877-897.
37. Habich, C., Burkart, V., Heat shock protein 60: regulatory role in innate immune cells. Cell Mol. Life Sci. 2007, 64, 742-751.
38. Saito, S., Sakai, M., Th1/Th2 balance in preeclampsia. J. Reprod. Immunol. 2003, 59, 161-173.
39. Borzychowski, A. M., Croy, B. A., Chan, W. L., Redman, C. W., Sargent, I. L., Changes in systemic type 1 and type 2 immunity in normal pregnancy and pre-eclampsia may be mediated by natural killer cells. Eur. J. Immunol. 2005, 35, 3054-3063.
40. Dieude, M., Gillis, M.-A., Theoret, J.-F., Thorin, E. et al., Autoantibodies to heat shock protein 60 (HSP60) promote thrombus formation in a murine model of arterial thrombosis. J. Thromb. Haeost. 2009, 7, 710-719.
41. Srivastava, S. K., Ramana, K. V., Bhatnagar, A., Role of aldose reductase and oxidative damage in diabetes and consequent potential for therapeutic options. Endocr. Rev. 2005, 26, 380-392.
42. Grune, T., Reinheckel, T., North, J. A., Li, R. et al., Ezrin turnover and cell shape changes catalyzed by proteasome in oxidatively stressed cells. FASEB J. 2002, 16, 1602-1610.
43. Demetriou, M., Binkert, C., Sukhu, B., Tenenbaum, H. C. et al., Fetuin/α2-HS glycoprotein is a transforming growth factor-β type II receptor mimic and cytokine antagonist. J. Biol. Chem 1996, 271, 12755-12761.
44. Wang, X.-Q., Hayes, M. T., Kempf, M., Fraser, J. F. et al., Fetuin-A a major fetal serum protein that promotes "wound closure" and scarless healing. J. Invest. Dermatol. 2008, 128, 753-757.
45. Morrish, D. W., Bhardwaj, D., Paras, M. T., Transforming growth factor β1 inhibits placental differentiation and human chorionic gonadotropin and human placental lactogen secretion. Endocrinology 1991, 129, 22-26.
46. Caniggia, I., Grisaru-Gravnosky, S., Kuliszewsky, M., Post, M. et al., Inhibition of TGF-beta 3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies. Eur. J. Clin. Invest. 1999, 103, 1641-1650.
47. Jones, R. L., Stoikos, C., Findlay, J. K., Salamonsen, L. A., TGF-β superfamily expression and actions in the endometrium and placenta. Reproduction 2006, 132, 217-232.
48. Saito, S., Nakashima, A., Shima, T., Ito, M., Th1/Th2/Th17 and regulatory T-cell paradigm in pregnancy. Am. J. Reprod. Immunol. 2010, 63, 601-610.
49. Poston, L., Endothelial dysfunction in pre-eclampsia. Pharmacol. Rep. 2006, 58, 69-74.
50. Girard, J., Ferre, P., Pegorier, J. P., Duee, P. H., Adaptations of glucose and fatty acid metabolism during perinatal period and suckling-weaning transition. Physiol. Rev. 1992, 72, 507-562.
51. Huch, G., Hohn, H. P., Denker, H. W., Identification of differentially expressed genes in human trophoblast cells by differential-display RT-PCR. Placenta 1998, 19, 557-567.
52. Wu, W. W., Wang, G., Baek, S. J., Shen, R. F., Comparative study of three proteomic quantitative methods, DIGE, cICAT, and iTRAQ, using 2D gel- or LC-MALDI TOF/TOF. J. Proteome Res. 2006, 5, 651-658.