Increased superoxide generation is associated with decreased superoxide dismutase activity and mRNA expression in placental trophoblast cells in pre-eclampsia

Placenta

Volumn 22, Issue 2-3, 2001, Pages 206-212

  Wang, Y ^a   Walsh, S W ^b  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MESSENGER RNA; RNA 18S; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ARTICLE; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; DELIVERY; DENSITY GRADIENT CENTRIFUGATION; DISEASE ASSOCIATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NORTHERN BLOTTING; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PLACENTA; PREECLAMPSIA; PREGNANCY; PREGNANCY DISORDER; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PURIFICATION; SPECTROPHOTOMETRY; STANDARD; TROPHOBLAST;

EID: 0034974930     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1053/plac.2000.0608     Document Type: Article

References (19)

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8. - production by human neutrophils. The preparation and assay of NADPH oxidase-containing particles from human neutrophils
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13. Peroxide induces vasoconstriction in the human placenta by stimulating thromboxane
14. Trophoblast and placental villous core production of lipid peroxides, thromboxane, and prostacyclin in pre-eclampsia
15. TNFα concentrations and mRNA expression are increased in preeclamptic placentas
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17. Placental mitochondria as a source of oxidative stress in pre-eclampsia
18. Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsia
19. The imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamin E in maternal blood