메뉴 건너뛰기




Volumn 47, Issue 9, 2011, Pages 669-681

Bevacizumab and ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

3' FLUOROTHYMIDINE F 18; BEVACIZUMAB; CAPECITABINE; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUORODEOXYGLUCOSE F 18; GEMCITABINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRINOTECAN; PACLITAXEL; TOPOTECAN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 80053934771     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.2011.47.9.1673557     Document Type: Review
Times cited : (7)

References (126)
  • 1
    • 77953151053 scopus 로고    scopus 로고
    • American Cancer Society. American Cancer Society: Atlanta, GA
    • American Cancer Society. Cancer Facts & Figures 2010. American Cancer Society: Atlanta, GA 2010.
    • (2010) Cancer Facts & Figures 2010
  • 2
    • 19744368302 scopus 로고    scopus 로고
    • Cancer of the ovary
    • Cannistra, S.A. Cancer of the ovary. N Engl J Med 2004, 351(24): 2519-29.
    • (2004) N Engl J Med , vol.351 , Issue.24 , pp. 2519-2529
    • Cannistra, S.A.1
  • 3
    • 0002949571 scopus 로고    scopus 로고
    • Treatment of relapsed epithelial ovarian carcinoma
    • American Society of Clinical Oncology: Alexandria, VA
    • Gore, M.E. Treatment of relapsed epithelial ovarian carcinoma. In: American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology: Alexandria, VA 2001.
    • (2001) American Society of Clinical Oncology Educational Book
    • Gore, M.E.1
  • 4
    • 63049115790 scopus 로고    scopus 로고
    • Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: A phase III trial of the Gynecologic Cancer Intergroup
    • Bookman, M.A., Brady, M.F., McGuire, W.P. et al. Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: a phase III trial of the Gynecologic Cancer Intergroup. J Clin Oncol 2009, 27(9): 1419-25.
    • (2009) J Clin Oncol , vol.27 , Issue.9 , pp. 1419-1425
    • Bookman, M.A.1    Brady, M.F.2    McGuire, W.P.3
  • 5
    • 0024549349 scopus 로고
    • Induction of angiogenesis during the transition from hyperplasia to neoplasia
    • DOI 10.1038/339058a0
    • Folkman, J., Watson, K., Ingber, D., Hanahan, D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 1989, 339(6219): 58-61. (Pubitemid 19115892)
    • (1989) Nature , vol.339 , Issue.6219 , pp. 58-61
    • Folkman, J.1    Watson, K.2    Ingber, D.3    Hanahan, D.4
  • 6
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman, J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990, 82(1): 4-6. (Pubitemid 20020880)
    • (1990) Journal of the National Cancer Institute , vol.82 , Issue.1 , pp. 4-6
    • Folkman, J.1
  • 7
    • 14644440555 scopus 로고    scopus 로고
    • Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
    • DOI 10.1200/JCO.2005.06.081
    • Hicklin, D.J., Ellis, L.M. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005, 23(5): 1011-27. (Pubitemid 46202320)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.5 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 8
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • DOI 10.1038/nature04483, PII NATURE04483
    • Ferrara, N., Kerbel, R.S. Angiogenesis as a therapeutic target. Nature 2005, 438(7070): 967-74. (Pubitemid 43093963)
    • (2005) Nature , vol.438 , Issue.7070 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 9
    • 0035862972 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in ovarian cyst fluid
    • DOI 10.1002/1097-0142(20010115)91:2<371::AID-CNCR1011>3.0.CO;2-2
    • Boss, E.A., Massuger, L.F., Thomas, C.M., Geurts-Moespot, A., Boonstra, H., Sweep, C.G. Vascular endothelial growth factor in ovarian cyst fluid. Cancer 2001, 91(2): 371-7. (Pubitemid 32099239)
    • (2001) Cancer , vol.91 , Issue.2 , pp. 371-377
    • Boss, E.A.1    Massuger, L.F.A.G.2    Thomas, C.M.G.3    Geurts-Moespot, A.4    Boonstra, H.5
  • 10
    • 0034796595 scopus 로고    scopus 로고
    • Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
    • DOI 10.1038/nm0901-987
    • Jain, R.K. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat Med 2001, 7(9): 987-9. (Pubitemid 32937367)
    • (2001) Nature Medicine , vol.7 , Issue.9 , pp. 987-989
    • Jain, R.K.1
  • 11
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet, P., Jain, R.K. Angiogenesis in cancer and other diseases. Nature 2000, 407(6801): 249-57.
    • (2000) Nature , vol.407 , Issue.6801 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 13
    • 28244490502 scopus 로고    scopus 로고
    • Angiogenesis in normal and neoplastic ovaries
    • DOI 10.1007/s10456-005-9001-1
    • Ramakrishnan, S., Subramanian, I.V., Yokoyama, Y., Geller, M. Angiogenesis in normal and neoplastic ovaries. Angiogenesis 2005, 8(2): 169-82. (Pubitemid 41712846)
    • (2005) Angiogenesis , vol.8 , Issue.2 , pp. 169-182
    • Ramakrishnan, S.1    Subramanian, I.V.2    Yokoyama, Y.3    Geller, M.4
  • 14
    • 34447502449 scopus 로고    scopus 로고
    • Experience with bevacizumab in the management of epithelial ovarian cancer
    • DOI 10.1200/JCO.2007.12.1509
    • Burger, R.A. Experience with bevacizumab in the management of epithelial ovarian cancer. J Clin Oncol 2007, 25(20): 2902-8. (Pubitemid 47123154)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.20 , pp. 2902-2908
    • Burger, R.A.1
  • 15
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger, D.R., Galli, S.J., Dvorak, A.M., Perruzzi, C.A., Harvey, V.S., Dvorak, H.F. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983, 219(4587): 983-5.
    • (1983) Science , vol.219 , Issue.4587 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 16
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
    • DOI 10.1200/JCO.2002.10.088
    • Dvorak, H.F. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 2002, 20(21): 4368-80. (Pubitemid 35266299)
    • (2002) Journal of Clinical Oncology , vol.20 , Issue.21 , pp. 4368-4380
    • Dvorak, H.F.1
  • 17
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • DOI 10.1038/nm0603-669
    • Ferrara, N., Gerber, H.P., LeCouter, J. The biology of VEGF and its receptors. Nat Med 2003, 9(6): 669-76. (Pubitemid 36749215)
    • (2003) Nature Medicine , vol.9 , Issue.6 , pp. 669-676
    • Ferrara, N.1    Gerber, H.-P.2    LeCouter, J.3
  • 18
    • 4444324696 scopus 로고    scopus 로고
    • VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma
    • DOI 10.1016/j.ygyno.2004.05.056, PII S0090825804003488
    • Chen, H., Ye, D., Xie, X., Chen, B., Lu, W. VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma. Gynecol Oncol 2004, 94(3): 630-5. (Pubitemid 39194453)
    • (2004) Gynecologic Oncology , vol.94 , Issue.3 , pp. 630-635
    • Chen, H.1    Ye, D.2    Xie, X.3    Chen, B.4    Lu, W.5
  • 20
    • 0033187946 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in ovarian cancer
    • Hazelton, D.A., Hamilton, T.C. Vascular endothelial growth factor in ovarian cancer. Curr Oncol Rep 1999, 1(1): 59-63.
    • (1999) Curr Oncol Rep , vol.1 , Issue.1 , pp. 59-63
    • Hazelton, D.A.1    Hamilton, T.C.2
  • 21
    • 0031455936 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) expression and survival in human epithelial ovarian carcinomas
    • DOI 10.1016/S0304-3835(97)00350-9, PII S0304383597003509
    • Hartenbach, E.M., Olson, T.A., Goswitz, J.J., Mohanraj, D., Twiggs, L.B., Carson, L.F., Ramakrishnan, S. Vascular endothelial growth factor (VEGF) expression and survival in human epithelial ovarian carcinomas. Cancer Lett 1997, 121(2): 169-75. (Pubitemid 28008916)
    • (1997) Cancer Letters , vol.121 , Issue.2 , pp. 169-175
    • Hartenbach, E.M.1    Olson, T.A.2    Goswitz, J.J.3    Mohanraj, D.4    Twiggs, L.B.5    Carson, L.F.6    Ramakrishnan, S.7
  • 22
    • 18844363423 scopus 로고    scopus 로고
    • The relationship of molecular markers of p53 function and angiogenesis to prognosis of stage I epithelial ovarian cancer
    • DOI 10.1158/1078-0432.CCR-04-0056
    • Goodheart, M.J., Ritchie, J.M., Rose, S.L., Fruehauf, J.P., De Young, B.R., Buller, R.E. The relationship of molecular markers of p53 function and angiogenesis to prognosis of stage I epithelial ovarian cancer. Clin Cancer Res 2005, 11(10): 3733-42. (Pubitemid 40685590)
    • (2005) Clinical Cancer Research , vol.11 , Issue.10 , pp. 3733-3742
    • Goodheart, M.J.1    Ritchie, J.M.2    Rose, S.L.3    Fruehauf, J.P.4    DeYoung, B.R.5    Buller, R.E.6
  • 25
    • 0345060442 scopus 로고    scopus 로고
    • Vascular Endothelial Growth Factor-Trap Decreases Tumor Burden, Inhibits Ascites, and Causes Dramatic Vascular Remodeling in an Ovarian Cancer Model
    • Byrne, A.T., Ross, L., Holash, J. et al. Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model. Clin Cancer Res 2003, 9(15): 5721-8. (Pubitemid 37499496)
    • (2003) Clinical Cancer Research , vol.9 , Issue.15 , pp. 5721-5728
    • Byrne, A.T.1    Ross, L.2    Holash, J.3    Nakanishi, M.4    Hu, L.5    Hofmann, J.I.6    Yancopoulos, G.D.7    Jaffe, R.B.8
  • 26
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta, L.G., Chen, H., O'Connor, S.J. et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997, 57(20): 4593-9. (Pubitemid 27441066)
    • (1997) Cancer Research , vol.57 , Issue.20 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3    Chisholm, V.4    Meng, Y.G.5    Krummen, L.6    Winkler, M.7    Ferrara, N.8
  • 27
    • 0026708632 scopus 로고
    • The vascular endothelial growth factor proteins: Identification of biologically relevant regions by neutralizing monoclonal antibodies
    • Kim, K.J., Li, B., Houck, K., Winer, J., Ferrara, N. The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors 1992, 7(1): 53-64.
    • (1992) Growth Factors , vol.7 , Issue.1 , pp. 53-64
    • Kim, K.J.1    Li, B.2    Houck, K.3    Winer, J.4    Ferrara, N.5
  • 28
    • 0031719516 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in ovarian cancer: Inhibition of ascites formation by immunoneutralization
    • Mesiano, S., Ferrara, N., Jaffe, R.B. Role of vascular endothelial growth factor in ovarian cancer: inhibition of ascites formation by immunoneutralization. Am J Pathol 1998, 153(4): 1249-56. (Pubitemid 28465848)
    • (1998) American Journal of Pathology , vol.153 , Issue.4 , pp. 1249-1256
    • Mesiano, S.1    Ferrara, N.2    Jaffe, R.B.3
  • 29
    • 0036782278 scopus 로고    scopus 로고
    • VEGF and the quest for tumour angiogenesis factors
    • DOI 10.1038/nrc909
    • Ferrara, N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2002, 2(10): 795-803. (Pubitemid 37328914)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.10 , pp. 795-803
    • Ferrara, N.1
  • 30
    • 84878742936 scopus 로고    scopus 로고
    • Data on file. Genentech, Inc., South San Francisco, CA: 2002
    • Data on file. Genentech, Inc., South San Francisco, CA: 2002.
  • 31
    • 0032962265 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor
    • Lin, Y.S., Nguyen, C., Mendoza, J.L., Escandon, E., Fei, D., Meng, Y.G., Modi, N.B. Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor. J Pharmacol Exp Ther 1999, 288(1): 371-8. (Pubitemid 29113511)
    • (1999) Journal of Pharmacology and Experimental Therapeutics , vol.288 , Issue.1 , pp. 371-378
    • Lin, Y.S.1    Nguyen, C.2    Mendoza, J.-L.3    Escandon, E.4    Fei, D.5    Meng, Y.G.6    Modi, N.B.7
  • 33
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar, F., Hurwitz, H.I., Fehrenbacher, L. et al. Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 2003, 21(1): 60-5.
    • (2003) J Clin Oncol , vol.21 , Issue.1 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3
  • 35
    • 0000397265 scopus 로고    scopus 로고
    • A randomized phase II trial comparing rHumAb VEGF (recombinant humanized monoclonal antibody to vascular endothelial growth factor) plus carboplatin/paclitaxel (CP) to CP alone in patients with stage III/IV NSCLC
    • 36th Annu Meet Amer Soc Clin Oncol (May 20-23, New Orleans) 2000 Abst 1896
    • DeVore, R., Fehrenbacher, L., Herbst, R. A randomized phase II trial comparing rHumAb VEGF (recombinant humanized monoclonal antibody to vascular endothelial growth factor) plus carboplatin/paclitaxel (CP) to CP alone in patients with stage III/IV NSCLC. Proc Am Soc Clin Oncol [36th Annu Meet Amer Soc Clin Oncol (May 20-23, New Orleans) 2000] 2000, 19: Abst 1896.
    • (2000) Proc Am Soc Clin Oncol , vol.19
    • DeVore, R.1    Fehrenbacher, L.2    Herbst, R.3
  • 36
    • 2942558419 scopus 로고    scopus 로고
    • Maximizing the potential of bevacizumab in cancer treatment
    • DOI 10.1634/theoncologist.9-suppl-1-36
    • Bergsland, E., Dickler, M.N. Maximizing the potential of bevacizumab in cancer treatment. Oncologist 2004, 9(Suppl. 1): 36-42. (Pubitemid 38747846)
    • (2004) Oncologist , vol.9 , Issue.SUPPL. 1 , pp. 36-42
    • Bergsland, E.1    Dickler, M.N.2
  • 38
    • 0010779376 scopus 로고    scopus 로고
    • Population pharmacokinetic (PK) analysis of bevacizumab (BV) in cancer subjects
    • 37th Annu Meet Amer Soc Clin Oncol (May 12-15, San Francisco) 2001 Abst 272
    • Hsei, V., Novotny, W., Margolin, K. et al. Population pharmacokinetic (PK) analysis of bevacizumab (BV) in cancer subjects. Proc Am Soc Clin Oncol [37th Annu Meet Amer Soc Clin Oncol (May 12-15, San Francisco) 2001] 2001, 20(Part 1): Abst 272.
    • (2001) Proc Am Soc Clin Oncol , vol.20 , Issue.PART 1
    • Hsei, V.1    Novotny, W.2    Margolin, K.3
  • 39
    • 0010775027 scopus 로고    scopus 로고
    • Pharmacokinetics (PK) of bevacizumab (BV) in colorectal cancer
    • Annu Meet Am Soc Clin Pharmacol Ther (ASCPT) (March 6-10, Orlando) 2001 Abst PI-98
    • Gaudreault, J., Lieberman, G., Kabbinavar, F. et al. Pharmacokinetics (PK) of bevacizumab (BV) in colorectal cancer. Clin Pharmacol Ther [Annu Meet Am Soc Clin Pharmacol Ther (ASCPT) (March 6-10, Orlando) 2001] 2001, 69(2): Abst PI-98.
    • (2001) Clin Pharmacol Ther , vol.69 , Issue.2
    • Gaudreault, J.1    Lieberman, G.2    Kabbinavar, F.3
  • 40
    • 80053992267 scopus 로고    scopus 로고
    • Population pharmacokinetics of bevacizumab
    • 44th Annu Meet Am Soc Clin Oncol (ASCO) (May 30-June 3, Chicago) Abst 14570
    • Gaudreault, J., Greig, G., Cosson, V., Gupta, M., Jumbe, N., Hooker, A. Population pharmacokinetics of bevacizumab. J Clin Oncol [44th Annu Meet Am Soc Clin Oncol (ASCO) (May 30-June 3, Chicago) 2008] 26(15, Suppl.): Abst 14570.
    • (2008) J Clin Oncol , vol.26 , Issue.15 SUPPL.
    • Gaudreault, J.1    Greig, G.2    Cosson, V.3    Gupta, M.4    Jumbe, N.5    Hooker, A.6
  • 41
    • 80053952334 scopus 로고    scopus 로고
    • package insert. Genentech, Inc., South San Francisco, CA
    • Avastin [package insert]. Genentech, Inc., South San Francisco, CA: 2009.
    • (2009) Avastin
  • 43
    • 36849019301 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: A Gynecologic Oncology Group study
    • DOI 10.1200/JCO.2007.11.5345
    • Burger, R.A., Sill, M.W., Monk, B.J., Greer, B.E., Sorosky, J.I. Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study. J Clin Oncol 2007, 25(33): 5165-71. (Pubitemid 350237599)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.33 , pp. 5165-5171
    • Burger, R.A.1    Sill, M.W.2    Monk, B.J.3    Greer, B.E.4    Sorosky, J.I.5
  • 46
    • 33745308428 scopus 로고    scopus 로고
    • Bevacizumab combination therapy in recurrent, platinum-refractory, epithelial ovarian carcinoma: A retrospective analysis
    • DOI 10.1002/cncr.21969
    • Wright, J.D., Hagemann, A., Rader, J.S. et al. Bevacizumab combination therapy in recurrent, platinum-refractory, epithelial ovarian carcinoma: A retrospective analysis. Cancer 2006, 107(1): 83-9. (Pubitemid 43939034)
    • (2006) Cancer , vol.107 , Issue.1 , pp. 83-89
    • Wright, J.D.1    Hagemann, A.2    Rader, J.S.3    Viviano, D.4    Gibb, R.K.5    Norris, L.6    Mutch, D.G.7    Powell, M.A.8
  • 47
    • 33745875210 scopus 로고    scopus 로고
    • Bevacizumab and weekly taxane chemotherapy demonstrates activity in refractory ovarian cancer
    • DOI 10.1016/j.ygyno.2006.01.030, PII S009082580600059X
    • Cohn, D.E., Valmadre, S., Resnick, K.E., Eaton, L.A., Copeland, L.J., Fowler, J.M. Bevacizumab and weekly taxane chemotherapy demonstrates activity in refractory ovarian cancer. Gynecol Oncol 2006, 102(2): 134-9. (Pubitemid 44056263)
    • (2006) Gynecologic Oncology , vol.102 , Issue.2 , pp. 134-139
    • Cohn, D.E.1    Valmadre, S.2    Resnick, K.E.3    Eaton, L.A.4    Copeland, L.J.5    Fowler, J.M.6
  • 48
    • 37849035249 scopus 로고    scopus 로고
    • Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: A trial of the California, Chicago, and Princess Margaret Hospital phase II consortia
    • Garcia, A.A., Hirte, H., Fleming, G. et al. Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia. J Clin Oncol 2008, 26(1): 76-82.
    • (2008) J Clin Oncol , vol.26 , Issue.1 , pp. 76-82
    • Garcia, A.A.1    Hirte, H.2    Fleming, G.3
  • 50
    • 71749110151 scopus 로고    scopus 로고
    • Preliminary results of a phase II study of oxaliplatin, docetaxel, and bevacizumab as first-line therapy of advanced cancer of the ovary, peritoneum, and fallopian tube
    • 45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009 Abst 5546
    • Rose, P., Drake, R., Braly, P. et al. Preliminary results of a phase II study of oxaliplatin, docetaxel, and bevacizumab as first-line therapy of advanced cancer of the ovary, peritoneum, and fallopian tube. J Clin Oncol [45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009] 2009, 27(15, Suppl.): Abst 5546.
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL.
    • Rose, P.1    Drake, R.2    Braly, P.3
  • 51
    • 66149121478 scopus 로고    scopus 로고
    • Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: A meta-analysis
    • Hapani, S., Chu, D., Wu, S. Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: a meta-analysis. Lancet Oncol 2009, 10(6): 559-68.
    • (2009) Lancet Oncol , vol.10 , Issue.6 , pp. 559-568
    • Hapani, S.1    Chu, D.2    Wu, S.3
  • 52
    • 27944456516 scopus 로고    scopus 로고
    • Managing patients treated with bevacizumab combination therapy
    • DOI 10.1159/000088481
    • Gordon, M.S., Cunningham, D. Managing patients treated with bevacizumab combination therapy. Oncology 2005, 69(Suppl. 3): 25-33. (Pubitemid 41680950)
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 25-33
    • Gordon, M.S.1    Cunningham, D.2
  • 53
    • 33748999448 scopus 로고    scopus 로고
    • Safety of bevacizumab plus chemotherapy as first-line treatment of patients with metastatic colorectal cancer: Updated results from a large observational registry in the US (BriTE)
    • 42nd Annu Meet Am Soc Clin Oncol (ASCO) (June 2-6, Atlanta) Abst 3536
    • Hedrick, E., Kozloff, M., Hainsworth, J.D. et al. Safety of bevacizumab plus chemotherapy as first-line treatment of patients with metastatic colorectal cancer: updated results from a large observational registry in the US (BriTE). J Clin Oncol [42nd Annu Meet Am Soc Clin Oncol (ASCO) (June 2-6, Atlanta) 2006, 24(18S): Abst 3536.
    • (2006) J Clin Oncol , vol.24 , Issue.18 S
    • Hedrick, E.1    Kozloff, M.2    Hainsworth, J.D.3
  • 54
    • 33947311852 scopus 로고    scopus 로고
    • What is the risk of bowel perforation associated with bevacizumab therapy in ovarian cancer?
    • DOI 10.1016/j.ygyno.2007.01.038, PII S0090825807000959
    • Han, E.S., Monk, B.J. What is the risk of bowel perforation associated with bevacizumab therapy in ovarian cancer? Gynecol Oncol 2007, 105(1): 3-6. (Pubitemid 46441477)
    • (2007) Gynecologic Oncology , vol.105 , Issue.1 , pp. 3-6
    • Han, E.S.1    Monk, B.J.2
  • 57
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • Miller, K., Wang, M., Gralow, J. et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007, 357(26): 2666-76.
    • (2007) N Engl J Med , vol.357 , Issue.26 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3
  • 59
    • 66149147757 scopus 로고    scopus 로고
    • Initial safety report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer
    • Allegra, C.J., Yothers, G., O'Connell, M.J. et al. Initial safety report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer. J Clin Oncol 2009, 27(20): 3385-90.
    • (2009) J Clin Oncol , vol.27 , Issue.20 , pp. 3385-3390
    • Allegra, C.J.1    Yothers, G.2    O'Connell, M.J.3
  • 60
    • 62449124416 scopus 로고    scopus 로고
    • Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil
    • Reck, M., von Pawel, J., Zatloukal, P. et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J Clin Oncol 2009, 27(8): 1227-34.
    • (2009) J Clin Oncol , vol.27 , Issue.8 , pp. 1227-1234
    • Reck, M.1    Von Pawel, J.2    Zatloukal, P.3
  • 61
    • 42949149159 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
    • Saltz, L.B., Clarke, S., Diaz-Rubio, E. et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008, 26(12): 2013-9.
    • (2008) J Clin Oncol , vol.26 , Issue.12 , pp. 2013-2019
    • Saltz, L.B.1    Clarke, S.2    Diaz-Rubio, E.3
  • 62
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • DOI 10.1200/JCO.2006.09.6305
    • Giantonio, B.J., Catalano, P.J., Meropol, N.J. et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 2007, 25(12): 1539-44. (Pubitemid 46733080)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.12 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3    O'Dwyer, P.J.4    Mitchell, E.P.5    Alberts, S.R.6    Schwartz, M.A.7    Benson III, A.B.8
  • 65
    • 80051549914 scopus 로고    scopus 로고
    • Combined weekly topotecan and biweekly bevacizumab in women with platinum-resistant ovarian, peritoneal, or fallopian tube cancer
    • McGonigle, K.F., Muntz, H.G., Vuky, J. et al. Combined weekly topotecan and biweekly bevacizumab in women with platinum-resistant ovarian, peritoneal, or fallopian tube cancer. Cancer 2011, 117(16): 3731-40.
    • (2011) Cancer , vol.117 , Issue.16 , pp. 3731-3740
    • McGonigle, K.F.1    Muntz, H.G.2    Vuky, J.3
  • 66
    • 45549099056 scopus 로고    scopus 로고
    • Efficacy and safety of bevacizumab plus erlotinib for patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer: A trial of the Chicago, PMH, and California Phase II Consortia
    • Nimeiri, H.S., Oza, A.M., Morgan, R.J. et al. Efficacy and safety of bevacizumab plus erlotinib for patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer: a trial of the Chicago, PMH, and California Phase II Consortia. Gynecol Oncol 2008, 110(1): 49-55.
    • (2008) Gynecol Oncol , vol.110 , Issue.1 , pp. 49-55
    • Nimeiri, H.S.1    Oza, A.M.2    Morgan, R.J.3
  • 67
    • 33644586050 scopus 로고    scopus 로고
    • Reversible posterior leukoencephalopathy syndrome and bevacizumab
    • Glusker, P., Recht, L., Lane, B. Reversible posterior leukoencephalopathy syndrome and bevacizumab. N Engl J Med 2006, 354(9): 980-2.
    • (2006) N Engl J Med , vol.354 , Issue.9 , pp. 980-982
    • Glusker, P.1    Recht, L.2    Lane, B.3
  • 68
    • 71649092006 scopus 로고    scopus 로고
    • Tracheoesophageal (TE) fistula development in a phase II trial of concurrent chemoradiation (CRT) and bevacizumab in limited-stage small-cell lung cancer (LS-SCLC)
    • 44th Annu Meet Am Soc Clin Oncol (ASCO) (May 30-June 3, Chicago) Abst 7554
    • Spigel, D., Hainsworth, J., Farley, C. et al. Tracheoesophageal (TE) fistula development in a phase II trial of concurrent chemoradiation (CRT) and bevacizumab in limited-stage small-cell lung cancer (LS-SCLC). J Clin Oncol [44th Annu Meet Am Soc Clin Oncol (ASCO) (May 30-June 3, Chicago) 2008] 26(15, Suppl.): Abst 7554.
    • (2008) J Clin Oncol , vol.26 , Issue.15 SUPPL.
    • Spigel, D.1    Hainsworth, J.2    Farley, C.3
  • 70
    • 70349632629 scopus 로고    scopus 로고
    • Pharmacokinetic analysis of irinotecan plus bevacizumab in patients with advanced solid tumors
    • Denlinger, C.S., Blanchard, R., Xu, L. et al. Pharmacokinetic analysis of irinotecan plus bevacizumab in patients with advanced solid tumors. Cancer Chemother Pharmacol 2009, 65(1): 97-105.
    • (2009) Cancer Chemother Pharmacol , vol.65 , Issue.1 , pp. 97-105
    • Denlinger, C.S.1    Blanchard, R.2    Xu, L.3
  • 71
    • 75549084013 scopus 로고    scopus 로고
    • Effects of bevacizumab on plasma concentration of irinotecan and its metabolites in advanced colorectal cancer patients receiving FOLFIRI with bevacizumab as second-line chemotherapy
    • Horita, Y., Yamada, Y., Hirashima, Y., Kato, K., Nakajima, T., Hamaguchi, T., Shimada, Y. Effects of bevacizumab on plasma concentration of irinotecan and its metabolites in advanced colorectal cancer patients receiving FOLFIRI with bevacizumab as second-line chemotherapy. Cancer Chemother Pharmacol 2010, 65(3): 467-71.
    • (2010) Cancer Chemother Pharmacol , vol.65 , Issue.3 , pp. 467-471
    • Horita, Y.1    Yamada, Y.2    Hirashima, Y.3    Kato, K.4    Nakajima, T.5    Hamaguchi, T.6    Shimada, Y.7
  • 73
    • 77954499682 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab (BEV) in the primary treatment of advanced epithelial ovarian cancer (EOC), primary peritoneal cancer (PPC) or fallopian tube cancer (FTC): A Gynecologic Oncology Group study
    • 46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010 Abst LBA1
    • Burger, R.A., Brady, M.F., Bookman, M.A. et al. Phase III trial of bevacizumab (BEV) in the primary treatment of advanced epithelial ovarian cancer (EOC), primary peritoneal cancer (PPC) or fallopian tube cancer (FTC): A Gynecologic Oncology Group study. J Clin Oncol [46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010] 2010, 28(18, Suppl.): Abst LBA1.
    • (2010) J Clin Oncol , vol.28 , Issue.18 SUPPL.
    • Burger, R.A.1    Brady, M.F.2    Bookman, M.A.3
  • 74
    • 84878688709 scopus 로고    scopus 로고
    • ICON 7: A phase III randomized gynecologic cancer intergroup trial of concurrent bevacizumab and chemotherapy followed by maintenance bevacizumab versus chemotherapy alone in women with newly diagnosed epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer
    • Abst LBA4
    • Perren, T., Swart, A.M., Pfisterer, J. et al. ICON 7: A phase III randomized gynecologic cancer intergroup trial of concurrent bevacizumab and chemotherapy followed by maintenance bevacizumab versus chemotherapy alone in women with newly diagnosed epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer. 35th Eur Soc Med Oncol (ESMO) Congr (Oct 8-12, Milan) 2010, Abst LBA4.
    • 35th Eur Soc Med Oncol (ESMO) Congr (Oct 8-12, Milan) 2010
    • Perren, T.1    Swart, A.M.2    Pfisterer, J.3
  • 75
    • 80054003628 scopus 로고    scopus 로고
    • Result of interim analysis of overall survival in the GCIG ICON7 phase III randomized trial of bevacizumab in women with newly diagnosed ovarian cancer
    • 47th Annu Meet Am Soc Clin Oncol (ASCO) (June 3-7, Chicago) 2011 Abst LBA5006
    • Kristensen, G., Perren, T., Qian, W. et al. Result of interim analysis of overall survival in the GCIG ICON7 phase III randomized trial of bevacizumab in women with newly diagnosed ovarian cancer. J Clin Oncol [47th Annu Meet Am Soc Clin Oncol (ASCO) (June 3-7, Chicago) 2011] 2011, 29(15, Suppl.): Abst LBA5006.
    • (2011) J Clin Oncol , vol.29 , Issue.15 SUPPL.
    • Kristensen, G.1    Perren, T.2    Qian, W.3
  • 76
    • 77951038269 scopus 로고    scopus 로고
    • Front-line bevacizumab in serous epithelial ovarian cancer: Biomarker analysis of the FINAVAST trial
    • Karihtala, P., Maenpaa, J., Turpeenniemi-Hujanen, T., Puistola, U. Front-line bevacizumab in serous epithelial ovarian cancer: biomarker analysis of the FINAVAST trial. Anticancer Res 2010, 30(3): 1001-6.
    • (2010) Anticancer Res , vol.30 , Issue.3 , pp. 1001-1006
    • Karihtala, P.1    Maenpaa, J.2    Turpeenniemi-Hujanen, T.3    Puistola, U.4
  • 77
    • 84878707941 scopus 로고    scopus 로고
    • STAC: A phase II study of carboplatin/paclitaxel/bevacizumab followed by randomization to either bevacizumab alone or erlotinib and bevacizumab in the upfront management of patients with ovarian, fallopian tube or peritoneal cancer
    • 42nd Annu Meet Soc Gynecol Oncol (March 6-9, Orlando) 2011 Abst 181
    • Campos, S., Atkinson, T., Berlin, S. et al. STAC: a phase II study of carboplatin/paclitaxel/bevacizumab followed by randomization to either bevacizumab alone or erlotinib and bevacizumab in the upfront management of patients with ovarian, fallopian tube or peritoneal cancer. Gynecol Oncol [42nd Annu Meet Soc Gynecol Oncol (March 6-9, Orlando) 2011] 2011, 120(Suppl. 1): Abst 181.
    • (2011) Gynecol Oncol , vol.120 , Issue.SUPPL. 1
    • Campos, S.1    Atkinson, T.2    Berlin, S.3
  • 78
    • 73949092398 scopus 로고    scopus 로고
    • Phase II study of carboplatin, paclitaxel, and bevacizumab with maintenance bevacizumab as first-line chemotherapy for advanced mullerian tumors
    • Penson, R.T., Dizon, D.S., Cannistra, S.A. et al. Phase II study of carboplatin, paclitaxel, and bevacizumab with maintenance bevacizumab as first-line chemotherapy for advanced mullerian tumors. J Clin Oncol 2010, 28(1): 154-9.
    • (2010) J Clin Oncol , vol.28 , Issue.1 , pp. 154-159
    • Penson, R.T.1    Dizon, D.S.2    Cannistra, S.A.3
  • 79
    • 84878718499 scopus 로고    scopus 로고
    • Tolerability and pharmacokinetics of intraperitoneal carboplatin and paclitaxel with intravenous bevacizumab
    • 46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010 Abst 5037
    • Krasner, C.N., Seiden, M., Roche, M.R. et al. Tolerability and pharmacokinetics of intraperitoneal carboplatin and paclitaxel with intravenous bevacizumab. J Clin Oncol [46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010] 2010, 28(15, Suppl.): Abst 5037.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Krasner, C.N.1    Seiden, M.2    Roche, M.R.3
  • 80
    • 77957746020 scopus 로고    scopus 로고
    • A phase II study of intravenous (IV) and intraperitoneal (IP) paclitaxel, IP cisplatin, and IV bevacizumab as first-line chemotherapy for optimal stage II or III ovarian, primary peritoneal, and fallopian tube cancer
    • 45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009 Abst 5539
    • Konner, J., Grabon, D., Pezzulli, S. et al. A phase II study of intravenous (IV) and intraperitoneal (IP) paclitaxel, IP cisplatin, and IV bevacizumab as first-line chemotherapy for optimal stage II or III ovarian, primary peritoneal, and fallopian tube cancer. J Clin Oncol [45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009] 2009, 27(15, Suppl.): Abst 5539.
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL.
    • Konner, J.1    Grabon, D.2    Pezzulli, S.3
  • 81
    • 74849109064 scopus 로고    scopus 로고
    • Phase II study of intravenous (IV) bevacizumab and paclitaxel, and intraperitoneal (IP) cisplatin, followed by bevacizumab consolidation for advanced ovarian (O) or peritoneal (P) cancers
    • 45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009 Abst 5540
    • McMeekin, D.D., Lanneau, G., Curiel, J., Moore, K., Walker, J.L., Mannel, R. Phase II study of intravenous (IV) bevacizumab and paclitaxel, and intraperitoneal (IP) cisplatin, followed by bevacizumab consolidation for advanced ovarian (O) or peritoneal (P) cancers. J Clin Oncol [45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009] 2009, 27(15, Suppl.): Abst 5540.
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL.
    • McMeekin, D.D.1    Lanneau, G.2    Curiel, J.3    Moore, K.4    Walker, J.L.5    Mannel, R.6
  • 85
    • 80053229517 scopus 로고    scopus 로고
    • OCEANS: A randomized, double-blinded, placebo-controlled phase III trial of chemotherapy with or without bevacizumab (BEV) in patients with platinum-sensitive recurrent epithelial ovarian (EOC), primary peritoneal (PPC), or fallopian tube cancer (FTC)
    • 47th Annu Meet Am Soc Clin Oncol (ASCO) (June 3-7, Chicago) 2011 Abst LBA5007
    • Aghajanian, C., Finkler, N.J., Rutherford, T. et al. OCEANS: A randomized, double-blinded, placebo-controlled phase III trial of chemotherapy with or without bevacizumab (BEV) in patients with platinum-sensitive recurrent epithelial ovarian (EOC), primary peritoneal (PPC), or fallopian tube cancer (FTC). J Clin Oncol [47th Annu Meet Am Soc Clin Oncol (ASCO) (June 3-7, Chicago) 2011] 2011, 29(15 Suppl.): Abst LBA5007.
    • (2011) J Clin Oncol , vol.29 , Issue.15 SUPPL.
    • Aghajanian, C.1    Finkler, N.J.2    Rutherford, T.3
  • 86
    • 77954243581 scopus 로고    scopus 로고
    • The predictive value of serum VEGF in multiresistant ovarian cancer patients treated with bevacizumab
    • Smerdel, M.P., Steffensen, K.D., Waldstrom, M., Brandslund, I., Jakobsen, A. The predictive value of serum VEGF in multiresistant ovarian cancer patients treated with bevacizumab. Gynecol Oncol 2010, 118(2): 167-71.
    • (2010) Gynecol Oncol , vol.118 , Issue.2 , pp. 167-171
    • Smerdel, M.P.1    Steffensen, K.D.2    Waldstrom, M.3    Brandslund, I.4    Jakobsen, A.5
  • 87
    • 33745923690 scopus 로고    scopus 로고
    • Salvage bevacizumab (rhuMAB VEGF)-based therapy after multiple prior cytotoxic regimens in advanced refractory epithelial ovarian cancer
    • DOI 10.1016/j.ygyno.2006.05.006, PII S0090825806003775
    • Monk, B.J., Han, E., Josephs-Cowan, C.A., Pugmire, G., Burger, R.A. Salvage bevacizumab (rhuMAB VEGF)-based therapy after multiple prior cytotoxic regimens in advanced refractory epithelial ovarian cancer. Gynecol Oncol 2006, 102(2): 140-4. (Pubitemid 44056265)
    • (2006) Gynecologic Oncology , vol.102 , Issue.2 , pp. 140-144
    • Monk, B.J.1    Han, E.2    Josephs-Cowan, C.A.3    Pugmire, G.4    Burger, R.A.5
  • 88
    • 78149433404 scopus 로고    scopus 로고
    • Bevacizumab plus low-dose metronomic oral cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer
    • Sanchez-Munoz, A., Mendiola, C., Perez-Ruiz, E. et al. Bevacizumab plus low-dose metronomic oral cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer. Oncology 2010, 79(1-2): 98-104.
    • (2010) Oncology , vol.79 , Issue.1-2 , pp. 98-104
    • Sanchez-Munoz, A.1    Mendiola, C.2    Perez-Ruiz, E.3
  • 89
    • 84878702421 scopus 로고    scopus 로고
    • Sequential angiogenic blockade for the treatment of recurrent ovarian cancer
    • 46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010 Abst 5083
    • Matulonis, U.A., Pereira, L., Lee, H. et al. Sequential angiogenic blockade for the treatment of recurrent ovarian cancer. J Clin Oncol [46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010] 2010, 28(15, Suppl.): Abst 5083.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Matulonis, U.A.1    Pereira, L.2    Lee, H.3
  • 90
    • 77957737979 scopus 로고    scopus 로고
    • Effects of weekly bevacizumab and pegylated liposomal doxorubicin in heavily pretreated patients with recurrent or progressed ovarian cancer
    • 45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009 Abst 5547
    • Kikuchi, Y., Kouta, H., Kikuchi, R. et al. Effects of weekly bevacizumab and pegylated liposomal doxorubicin in heavily pretreated patients with recurrent or progressed ovarian cancer. J Clin Oncol [45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009] 2009, 27(15, Suppl.): Abst 5547.
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL.
    • Kikuchi, Y.1    Kouta, H.2    Kikuchi, R.3
  • 91
    • 80053935580 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin (PLD) with bevacizumab (B) in second-line treatment of ovarian cancer (OC): Pharmacokinetics (PK), safety, and preliminary outcome results
    • 45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009 Abst 5548
    • Muggia, F., Boyd, L., Liebes, L. et al. Pegylated liposomal doxorubicin (PLD) with bevacizumab (B) in second-line treatment of ovarian cancer (OC): Pharmacokinetics (PK), safety, and preliminary outcome results. J Clin Oncol [45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009] 2009, 27(15, Suppl.): Abst 5548.
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL.
    • Muggia, F.1    Boyd, L.2    Liebes, L.3
  • 93
    • 79952680888 scopus 로고    scopus 로고
    • A phase II study of bevacizumab with nab-paclitaxel in patients with recurrent, platinum-resistant primary epithelial patients with recurrent, platinum-resistant primary epithelial ovarian or primary peritoneal carcinoma
    • 46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010 Abst 5009
    • Tillmanns, T., Lowe, M., Schwartzberg, L., Walker, M., Stepanski, E. A phase II study of bevacizumab with nab-paclitaxel in patients with recurrent, platinum-resistant primary epithelial patients with recurrent, platinum-resistant primary epithelial ovarian or primary peritoneal carcinoma. J Clin Oncol [46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010] 2010, 28(15, Suppl.): Abst 5009.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Tillmanns, T.1    Lowe, M.2    Schwartzberg, L.3    Walker, M.4    Stepanski, E.5
  • 94
    • 80053995857 scopus 로고    scopus 로고
    • Phase II trial of docetaxel and bevacizumab in recurrent ovarian cancer within 12 months of prior platinum-based chemotherapy
    • 42nd Annu Meet Soc Gynecol Oncol (March 6-9, Orlando) 2011 Abst 192
    • Wenham, R., LaPolla, J., Hui-Yi, L. et al. Phase II trial of docetaxel and bevacizumab in recurrent ovarian cancer within 12 months of prior platinum-based chemotherapy. Gynecol Oncol [42nd Annu Meet Soc Gynecol Oncol (March 6-9, Orlando) 2011] 2011, 120(Suppl. 1): Abst 192.
    • (2011) Gynecol Oncol , vol.120 , Issue.SUPPL. 1
    • Wenham, R.1    LaPolla, J.2    Hui-Yi, L.3
  • 95
    • 84878722975 scopus 로고    scopus 로고
    • Addition of bevacizumab to weekly paclitaxel significantly improves progression-free survival in heavily pretreated, recurrent epithelial ovarian cancer
    • 41st Annu Meet Soc Gynecol Oncol (March 10-17, San Francisco) 2010 Abst 120
    • Hurt, J., Backes, F., Rheaume, S., et al. Addition of bevacizumab to weekly paclitaxel significantly improves progression-free survival in heavily pretreated, recurrent epithelial ovarian cancer. Gynecol Oncol [41st Annu Meet Soc Gynecol Oncol (March 10-17, San Francisco) 2010] 2010, 116(3, Suppl.): Abst 120.
    • (2010) Gynecol Oncol , vol.116 , Issue.3 SUPPL.
    • Hurt, J.1    Backes, F.2    Rheaume, S.3
  • 96
    • 84878710968 scopus 로고    scopus 로고
    • Feasibility of bevacizumab (BEV) plus chemotherapy in heavily pretreated ovarian cancer (OC) patients (pts): A retrospective study
    • 46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010 Abst e15509
    • Asmane, I., Guastalla, J.P., Meeus, P. et al. Feasibility of bevacizumab (BEV) plus chemotherapy in heavily pretreated ovarian cancer (OC) patients (pts): A retrospective study. J Clin Oncol [46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010] 2010, 28(15, Suppl.): Abst e15509.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Asmane, I.1    Guastalla, J.P.2    Meeus, P.3
  • 97
    • 80053981461 scopus 로고    scopus 로고
    • The efficacy and toxicity of bevacizumab plus gemcitabine in patients with recurrent ovarian cancer
    • 39th Annu Meet Soc Gynecol Oncol (March 9-12, Tampa) 2008
    • Bevis, K.S., Numnum, T.M., Shipman, K.A., Makhija, S., Barnes, M.N., Straughn, J. The efficacy and toxicity of bevacizumab plus gemcitabine in patients with recurrent ovarian cancer. Gynecol Oncol [39th Annu Meet Soc Gynecol Oncol (March 9-12, Tampa) 2008] 2008, 108(3, Suppl. 1): S119.
    • (2008) Gynecol Oncol , vol.108 , Issue.3 SUPPL. 1
    • Bevis, K.S.1    Numnum, T.M.2    Shipman, K.A.3    Makhija, S.4    Barnes, M.N.5    Straughn, J.6
  • 98
    • 56449105264 scopus 로고    scopus 로고
    • Combination gemcitabine, platinum, and bevacizumab for the treatment of recurrent ovarian cancer
    • Richardson, D.L., Backes, F.J., Seamon, L.G. et al. Combination gemcitabine, platinum, and bevacizumab for the treatment of recurrent ovarian cancer. Gynecol Oncol 2008, 111(3): 461-6.
    • (2008) Gynecol Oncol , vol.111 , Issue.3 , pp. 461-466
    • Richardson, D.L.1    Backes, F.J.2    Seamon, L.G.3
  • 99
    • 84878717945 scopus 로고    scopus 로고
    • A phase II study of gemcitabine, carboplatin and bevacizumab for the treatment of platinum-sensitive recurrent ovarian cancer
    • 42nd Annu Meet Soc Gynecol Oncol (March 6-9, Orlando) 2011 Abst 69
    • Eisenhauer, E., Zanagnolo, V., Cohn, D.E. et al. A phase II study of gemcitabine, carboplatin and bevacizumab for the treatment of platinum-sensitive recurrent ovarian cancer. Gynecol Oncol [42nd Annu Meet Soc Gynecol Oncol (March 6-9, Orlando) 2011] 2011, 120(Suppl. 1): Abst 69.
    • (2011) Gynecol Oncol , vol.120 , Issue.SUPPL. 1
    • Eisenhauer, E.1    Zanagnolo, V.2    Cohn, D.E.3
  • 100
    • 78049477139 scopus 로고    scopus 로고
    • Overexpression of tumor vascular endothelial growth factor A may portend an increased likelihood of progression in a phase II trial of bevacizumab and erlotinib in resistant ovarian cancer
    • Chambers, S.K., Clouser, M.C., Baker, A.F. et al. Overexpression of tumor vascular endothelial growth factor A may portend an increased likelihood of progression in a phase II trial of bevacizumab and erlotinib in resistant ovarian cancer. Clin Cancer Res 2010, 16(21): 5320-8.
    • (2010) Clin Cancer Res , vol.16 , Issue.21 , pp. 5320-5328
    • Chambers, S.K.1    Clouser, M.C.2    Baker, A.F.3
  • 102
    • 78649537524 scopus 로고    scopus 로고
    • Biomarkers to predict the clinical efficacy of bevacizumab in cancer
    • Jubb, A.M., Harris, A.L. Biomarkers to predict the clinical efficacy of bevacizumab in cancer. Lancet Oncol 2010, 11(12): 1172-83.
    • (2010) Lancet Oncol , vol.11 , Issue.12 , pp. 1172-1183
    • Jubb, A.M.1    Harris, A.L.2
  • 103
    • 72249083700 scopus 로고    scopus 로고
    • Association of computed tomography morphologic criteria with pathologic response and survival in patients treated with bevacizumab for colorectal liver metastases
    • Chun, Y.S., Vauthey, J.N., Boonsirikamchai, P. et al. Association of computed tomography morphologic criteria with pathologic response and survival in patients treated with bevacizumab for colorectal liver metastases. JAMA 2009, 302(21): 2338-44.
    • (2009) JAMA , vol.302 , Issue.21 , pp. 2338-2344
    • Chun, Y.S.1    Vauthey, J.N.2    Boonsirikamchai, P.3
  • 104
    • 57849117384 scopus 로고    scopus 로고
    • New response evaluation criteria in solid tumours: Revised RECIST guideline
    • version 1.1
    • Eisenhauer, E.A., Therasse, P., Bogaerts, J. et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009, 45(2): 228-47.
    • (2009) Eur J Cancer , vol.45 , Issue.2 , pp. 228-247
    • Eisenhauer, E.A.1    Therasse, P.2    Bogaerts, J.3
  • 105
    • 62349110279 scopus 로고    scopus 로고
    • A vasculature-targeting regimen of preoperative docetaxel with or without bevacizumab for locally advanced breast cancer: Impact on angiogenic biomarkers
    • Baar, J., Silverman, P., Lyons, J. et al. A vasculature-targeting regimen of preoperative docetaxel with or without bevacizumab for locally advanced breast cancer: impact on angiogenic biomarkers. Clin Cancer Res 2009, 15(10): 3583-90.
    • (2009) Clin Cancer Res , vol.15 , Issue.10 , pp. 3583-3590
    • Baar, J.1    Silverman, P.2    Lyons, J.3
  • 106
    • 77956265269 scopus 로고    scopus 로고
    • Perfusion MRI in the early clinical development of antivascular drugs: Decorations or decision making tools?
    • Zweifel, M., Padhani, A.R. Perfusion MRI in the early clinical development of antivascular drugs: decorations or decision making tools? Eur J Nucl Med Mol Imaging 2010, 37(Suppl. 1): S164-82.
    • (2010) Eur J Nucl Med Mol Imaging , vol.37 , Issue.SUPPL. 1
    • Zweifel, M.1    Padhani, A.R.2
  • 109
    • 73249128451 scopus 로고    scopus 로고
    • Efficacy and safety of gemcitabine, oxaliplatin, and bevacizumab in advanced biliary-tract cancers and correlation of changes in 18-fluorodeoxyglucose PET with clinical outcome: A phase 2 study
    • Zhu, A.X., Meyerhardt, J.A., Blaszkowsky, L.S. et al. Efficacy and safety of gemcitabine, oxaliplatin, and bevacizumab in advanced biliary-tract cancers and correlation of changes in 18-fluorodeoxyglucose PET with clinical outcome: a phase 2 study. Lancet Oncol 2010, 11(1): 48-54.
    • (2010) Lancet Oncol , vol.11 , Issue.1 , pp. 48-54
    • Zhu, A.X.1    Meyerhardt, J.A.2    Blaszkowsky, L.S.3
  • 111
    • 0019790278 scopus 로고
    • Reactivity of a monoclonal antibody with human ovarian carcinoma
    • Bast, R.C., Jr., Feeney, M., Lazarus, H., Nadler, L.M., Colvin, R.B., Knapp, R.C. Reactivity of a monoclonal antibody with human ovarian carcinoma. J Clin Invest 1981, 68(5): 1331-7. (Pubitemid 12235035)
    • (1981) Journal of Clinical Investigation , vol.68 , Issue.5 , pp. 1331-1337
    • Bast Jr., R.C.1    Feeney, M.2    Lazarus, H.3
  • 113
    • 70249090419 scopus 로고    scopus 로고
    • Nadir CA-125 level is an independent prognostic factor in advanced epithelial ovarian cancer
    • Kang, S., Seo, S.S., Park, S.Y. Nadir CA-125 level is an independent prognostic factor in advanced epithelial ovarian cancer. J Surg Oncol 2009, 100(3): 244-7.
    • (2009) J Surg Oncol , vol.100 , Issue.3 , pp. 244-247
    • Kang, S.1    Seo, S.S.2    Park, S.Y.3
  • 116
    • 84878716583 scopus 로고    scopus 로고
    • CA125 response to bevacizumab in recurrent ovarian cancer
    • 46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010 Abst 5077
    • O'Cearbhaill, R.E., Zhou, Q., Iasonos, A. et al. CA125 response to bevacizumab in recurrent ovarian cancer. J Clin Oncol [46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010] 2010, 28(15, Suppl.): Abst 5077.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • O'Cearbhaill, R.E.1    Zhou, Q.2    Iasonos, A.3
  • 117
    • 67649921334 scopus 로고    scopus 로고
    • Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: A multidisciplinary phase II study
    • Willett, C.G., Duda, D.G., di Tomaso, E. et al. Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. J Clin Oncol 2009, 27(18): 3020-6.
    • (2009) J Clin Oncol , vol.27 , Issue.18 , pp. 3020-3026
    • Willett, C.G.1    Duda, D.G.2    Di Tomaso, E.3
  • 118
    • 40949111793 scopus 로고    scopus 로고
    • Cell adhesion molecules, vascular endothelial growth factor, and basic fibroblast growth factor in patients with non-small cell lung cancer treated with chemotherapy with or without bevacizumab - An Eastern Cooperative Oncology Group study
    • DOI 10.1158/1078-0432.CCR-07-1154
    • Dowlati, A., Gray, R., Sandler, A.B., Schiller, J.H., Johnson, D.H. Cell adhesion molecules, vascular endothelial growth factor, and basic fibroblast growth factor in patients with non-small cell lung cancer treated with chemotherapy with or without bevacizumab - an Eastern Cooperative Oncology Group Study. Clin Cancer Res 2008, 14(5): 1407-12. (Pubitemid 351413922)
    • (2008) Clinical Cancer Research , vol.14 , Issue.5 , pp. 1407-1412
    • Dowlati, A.1    Gray, R.2    Sandler, A.B.3    Schiller, J.H.4    Johnson, D.H.5
  • 119
    • 78649593334 scopus 로고    scopus 로고
    • Circulating bascular endothelial growth factor (VEGF) as a biomarker for bevacizumab-based therapy in metastatic colorectal, non-small cell lung, and renal cell cancers: Analysis of phase III studies
    • [46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010] Abst 10519
    • Bernaards, C., Hegde, P., Chen, D. et al. Circulating bascular endothelial growth factor (VEGF) as a biomarker for bevacizumab-based therapy in metastatic colorectal, non-small cell lung, and renal cell cancers: Analysis of phase III studies. J Clin Oncol [46th Annu Meet Am Soc Clin Oncol (ASCO) (June 4-8, Chicago) 2010] 2010, 28(15, Suppl.): Abst 10519.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Bernaards, C.1    Hegde, P.2    Chen, D.3
  • 120
    • 34249721065 scopus 로고    scopus 로고
    • Bevacizumab reduces VEGF expression in patients with relapsed and refractory acute myeloid leukemia without clinical antileukemic activity [6]
    • DOI 10.1038/sj.leu.2404632, PII 2404632
    • Zahiragic, L., Schliemann, C., Bieker, R. et al. Bevacizumab reduces VEGF expression in patients with relapsed and refractory acute myeloid leukemia without clinical antileukemic activity. Leukemia 2007, 21(6): 1310-2. (Pubitemid 46831824)
    • (2007) Leukemia , vol.21 , Issue.6 , pp. 1310-1312
    • Zahiragic, L.1    Schliemann, C.2    Bieker, R.3    Thoennissen, N.H.4    Burow, K.5    Kramer, C.6    Zuhlsdorf, M.7    Berdel, W.E.8    Mesters, R.M.9
  • 123
    • 54449099774 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide and capecitabine combined with bevacizumab in advanced breast cancer
    • Dellapasqua, S., Bertolini, F., Bagnardi, V. et al. Metronomic cyclophosphamide and capecitabine combined with bevacizumab in advanced breast cancer. J Clin Oncol 2008, 26(30): 4899-905.
    • (2008) J Clin Oncol , vol.26 , Issue.30 , pp. 4899-4905
    • Dellapasqua, S.1    Bertolini, F.2    Bagnardi, V.3
  • 124
    • 77953538055 scopus 로고    scopus 로고
    • Clinical benefit of bevacizumab plus first-line docetaxel in elderly patients with locally recurrent or metastatic breast cancer
    • 45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009 Abst 1094
    • Pivot, X., Verma, S., Thomssen, C. et al. Clinical benefit of bevacizumab plus first-line docetaxel in elderly patients with locally recurrent or metastatic breast cancer. J Clin Oncol [45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009] 2009, 27(15, Suppl.): Abst 1094.
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL.
    • Pivot, X.1    Verma, S.2    Thomssen, C.3
  • 125
    • 70249097518 scopus 로고    scopus 로고
    • RIBBON-1: Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for firstline treatment of HER2-negative locally recurrent or metastatic breast cancer (MBC)
    • 45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009 Abst 1005
    • Robert, N.J., Dieras, V., Glaspy, J. et al. RIBBON-1: Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for firstline treatment of HER2-negative locally recurrent or metastatic breast cancer (MBC). J Clin Oncol [45th Annu Meet Am Soc Clin Oncol (ASCO) (May 29-June 2, Orlando) 2009] 2009, 27(15, Suppl.): Abst 1005.
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL.
    • Robert, N.J.1    Dieras, V.2    Glaspy, J.3
  • 126
    • 79953893326 scopus 로고    scopus 로고
    • At what cost does a potential survival advantage of bevacizumab make sense for the primary treatment of ovarian cancer? A cost-effectiveness analysis
    • Cohn, D.E., Kim, K.H., Resnick, K.E., O'Malley, D.M., Straughn, J.M., Jr. At what cost does a potential survival advantage of bevacizumab make sense for the primary treatment of ovarian cancer? A cost-effectiveness analysis. J Clin Oncol 2011, 29(10): 1247-51.
    • (2011) J Clin Oncol , vol.29 , Issue.10 , pp. 1247-1251
    • Cohn, D.E.1    Kim, K.H.2    Resnick, K.E.3    O'Malley, D.M.4    Straughn Jr., J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.