Protein concentration prediction in cell cultures: The next stage in near infrared bioprocess analysis

Spectroscopy Europe

Volumn 23, Issue 3, 2011, Pages 18-21

  Strother, Todd ^a  

^a Thermo Fisher Scientific   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPROCESSES; CHEMOMETRIC ANALYSIS; CHINESE HAMSTER OVARY CELLS; DYNAMIC CELL CULTURES; FEASIBILITY STUDIES; FOURIER TRANSFORM NEAR INFRARED; NEAR INFRARED; PARTIAL LEAST SQUARES; PLS ANALYSIS; PREDICTIVE CAPABILITIES; PROCESS ANALYZERS; PROTEIN CONCENTRATIONS; TARGET PROTEINS;

CELLS; FOURIER TRANSFORMS; INFRARED DEVICES; LEAST SQUARES APPROXIMATIONS; PROTEINS;

CELL CULTURE;

EID: 80053928421     PISSN: 09660941     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

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2. R. A. Naughton, T. R. Rohrer and R. L Gentz, "Method and system for providing real-time, in situ biomanufacturing process monitoring and control in response to IR spectroscopy", Patent US 2002/0155541 Al, October 24, 2002.
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6. S. Vaidyanathan, LM. Harvey and B. McNeil, "Deconvolution of near-infrared spectral information for monitoring mycelial biomass and other key analytes in a submerged fungal bioprocess", Anal. Chim. Acta 428, 41-59 (2001).