The encapsulation of β-lapachone in 2-hydroxypropyl-β- cyclodextrin inclusion complex into liposomes: A physicochemical evaluation and molecular modeling approach

European Journal of Pharmaceutical Sciences

Volumn 44, Issue 3, 2011, Pages 332-340

  Cavalcanti, Isabella M F ^a   Mendona, Elisângela A M ^a,b   Lira, Mariane C B ^a   Honrato, Sara B ^c   Camara, Celso A ^d   Amorim, Rosa V S ^e   Filho, Josué Mendes ^c   Rabello, Marcelo M ^a   Hernandes, Marcelo Z ^a   Ayala, Alejandro P ^c   Santos Magalhães, Nereide S ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b STATE UNIVERSITY OF PARAÍBA   (Brazil)

^c FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^d UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO   (Brazil)

^e FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

Author keywords

Lapachone; 2 Hydroxypropyl cyclodextrin; Inclusion complex; Kinetics; Liposomes; Molecular modeling

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; BETA LAPACHONE;

AQUEOUS SOLUTION; ARTICLE; CANCER RESEARCH; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; ENCAPSULATION; FREEZE DRYING; HYDROGEN BOND; IN VITRO STUDY; LIPOSOMAL DELIVERY; MOLECULAR INTERACTION; MOLECULAR MODEL; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAMAN SPECTROMETRY; SCANNING ELECTRON MICROSCOPY; STOICHIOMETRY; THERMOGRAVIMETRY; THERMOSTABILITY;

ADJUVANTS, PHARMACEUTIC; BETA-CYCLODEXTRINS; DRUG COMPOUNDING; FREEZE DRYING; LIPOSOMES; MICROSCOPY, ELECTRON, SCANNING; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NAPHTHOQUINONES; PHASE TRANSITION; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTRUM ANALYSIS, RAMAN; SURFACE PROPERTIES;

EID: 80053918074     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.08.011     Document Type: Article

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