Polymorphisms in the P450 c17 (17-hydroxylase/17, 20-lyase) gene: Association with estradiol and testosterone concentration in hypospadias

Urology

Volumn 78, Issue 4, 2011, Pages 902-907

  Yadav, Chandra Shekhar ^a   Bajpai, Minu ^b   Kumar, Vivek ^a   Datta, Sudip Kumar ^a   Gupta, Piyush ^a   Ahmed, Rafat Sultana ^a   Banerjee, Basu Dev ^a  

^a UNIVERSITY OF DELHI   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 17; ESTRADIOL; TESTOSTERONE;

ARTICLE; CHILD; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HYPOSPADIAS; INFANT; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHOOL CHILD;

CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; ESTRADIOL; GENOTYPE; HOMOZYGOTE; HUMANS; HYPOSPADIAS; INFANT; MALE; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; STEROID 17-ALPHA-HYDROXYLASE; TESTOSTERONE;

EID: 80053895909     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2011.04.021     Document Type: Article

References (30)

1. L.S. Baskin, T. Colborn, and K. Himes Hypospadias and endocrine disruption: is there a connection? Environ Health Perspect 109 2001 1175 1183
2. L.J. Paulozzi, J.D. Erickson, and R.J. Jackson Hypospadias trends in two US surveillance systems Pediatrics 100 1997 831 834
3. N.M. Holmes, W.L. Miller, and L.S. Baskin Lack of defects in androgen production in children with hypospadias J Clin Endocrinol Metab 89 2004 2811 2816
4. N.E. Skakkebæk, E. Rajpert-De Meyts, and K.M. Main Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects Hum Reprod 16 2001 972 978
5. J. Toppari, J.C. Larsen, and P. Christiansen Male reproductive health and environmental xenoestrogens Environ Health Perspect 104 Suppl 4 1996 741 803
6. L.J. Picado, and W.L. Miller Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): similarity with the gene for P450c21 DNA 6 1987 439 448
7. A.H. Carey, D. Waterworth, and K. Patel Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17 Hum Mol Genet 3 1994 1873 1876
8. B.C. Chung, L.J. Picado, and M. Haniu Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues Proc Natl Acad Sci U S A 84 1987 407 411
9. H.S. Feigelson, L.S. Shames, and M.C. Pike Cytochrome P450c17alpha gene (CYP17) polymorphism is associated with serum estrogen and progesterone concentrations Cancer Res 58 1998 585 587
10. C.A. Haiman, S.E. Hankinson, and D. Spiegelman The relationship between a polymorphism in CYP17 with plasma hormone levels and breast cancer Cancer Res 59 1999 1015 1020
11. D.H. Geller, R.J. Auchus, B.B. Mendona, and W.L. Miller The genetic and functional basis of isolated 17,20-lyase deficiency Nat Genet 17 1997 201 205
12. J. Somner, S. McLellan, and J. Cheung Polymorphisms in the P450 c17 (17-hydroxylase/17,20-lyase) and P450 c19 (aromatase) Genes: Association with Serum Sex Steroid Concentrations and Bone Mineral Density in Postmenopausal Women J Clin Endocrinol Metab 89 2004 344 351
13. I.A. Aaronson, M.A. Cakmak, and L.L. Key Defects of the testosterone biosynthetic pathway in boys with hypospadias J Urol 157 1997 1884 1888
14. A.M. Dunning, C.S. Healey, and P.D. Pharoah No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer Br J Cancer 77 1998 2045 2047
15. N.E. Allen, M.S. Forrest, and T.J. Key The association between polymorphisms in the CYP17 and 5alpha-reductase (SRD5A2) genes and serum androgen concentrations in men Cancer Epidemiol Biomarkers Prev 10 2001 185 189
16. M.J. Messina, V. Persky, K.D. Setchell, and S. Barnes Soy intake and cancer risk: a review of the in vitro and in vivo data Nutr Cancer 21 1994 113 131
17. R.S. Kaldas, and C.L. Hughes Jr. Reproductive and general metabolic effects of phytoestrogens in mammals Reprod Toxicol 3 1989 81 89
18. O. Akre, H.A. Boyd, and M. Ahlgren Maternal and Gestational Risk Factors for hypospadias Environ Health Perspect 116 2008 1071 1076
19. A. Cassidy, S. Bingham, and K.D. Setchell Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women Am J Clin Nutr 60 1994 333 340
20. A.M. Andersson, N. Jørgensen, L. Frydelund-Larsen, E. Rajpert-De Meyts, and N.E. Skakkebaek Impaired Leydig cell function in infertile men: a study of 357 idiopathic infertile men and 318 proven fertile controls J Clin Endocrinol Metab 89 2004 3161 3167
21. A.J. Mancab, and C. Zouves Hypospadias after assisted reproduction incorporating in vitro fertilization and gamete intrfallopin transfer Fertil Steril 56 1991 918 922
22. R.I. Silver, R. Rodriguez, and T.S.K. Chang In vitro fertilization is associated with an increased risk of hypospadias J Urol 161 1999 1945 1957
23. A.M. Soto, C. Sonnenschein, and K.L. Chung The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants Environ Health Perspect 103 Suppl 7 1995 113 122
24. V. Kumar, C.S. Yadav, and S. Singh CYP 1A1 polymorphism and organochlorine pesticides levels in the etiology of prostate cancer Chemosphere 81 2010 464 468
25. S. Koifman, R.J. Koifman, and A. Meyer Human reproductive system disturbances and pesticide exposure in Brazil Cad Saude Publ 18 2002 435 445
26. F. Laden, L.M. Neas, and D. Spiegelman Predictors of plasma concentrations of DDE and PCBs in a group of U.S. women Environ Health Perspect 107 1999 75 81
27. R. Pathak, S.G. Suke, and T. Ahmed Organochlorine pesticide residue levels and oxidative stress in preterm delivery cases Hum Exp Toxicol 29 2010 351 358
28. C.S. Yadav, M. Bajpai, and V. Kumar Polymorphism in CYP1A1, GSTM1, GSTT1 genes and organochlorine pesticides in the etiology of hypospadias Hum Exp Toxicol 2010 In press
29. W.R. Kelce, C.R. Stone, and S.C. Laws Persistent DDT metabolite p, p DDE is a potent androgen receptor antagonist Nature 15 1995 581 585
30. O.V. Martin, T. Shialis, and J.N. Lester Testicular dysgenesis syndrome and the estrogen hypothesis: a quantitative meta-analysis Environ Health Perspect 116 2008 149 157