No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer

British Journal of Cancer

Volumn 77, Issue 11, 1998, Pages 2045-2047

  Dunning, A M ^a   Healey, C S ^a   Pharoah, P D P ^a,c   Foster, N A ^a   Lipscombe, J M ^c   Redman, K L ^b   Easton, D F ^b   Day, N E ^c   Ponder, B A J ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

617 gene polymorphism; Breast cancer; Steroid metabolism

Indexed keywords

STEROID;

ADULT; ADVANCED CANCER; ALLELE; ARTICLE; BREAST CANCER; CANCER RISK; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; STEROID METABOLISM; UNITED KINGDOM;

EID: 0031801508     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.340     Document Type: Article

References (5)

1. Carey AH, Waterworth D, Patel K, White D, Little J, Novelli P, Franks S and Williamson R (1997) Polycystic ovaries and premature male-pattern baldness are associated with one allele of the steroid metabolism gene CYP17. Hum Mol Genet 10: 1873-1876
2. Easton DF, Peto J and Babiker AGAG (1991) Floating absolute risk: an alternative to relative risk in survival and case-control analysis avoiding an arbitrary reference group. Stat Med 10: 1025-1035
3. Feigelson HS, Coetzee GA, Kolonel LN, Ross RK and Henderson BE (1997) A polymorphism in the CYP17 gene increases the risk of breast cancer. Cancer Res 57: 1063-1065
4. Kelsey JL, Gammon MD and John EM (1993) Reproductive factors and breast cancer. Epidemiol Rev 15: 36-47
5. Riboli E and Kaaks R (1997) The EPIC project: rationale and study design. Int J Epidemiol 26: S6-S14