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Volumn 118, Issue 14, 2011, Pages 3901-3910

ABT-737 is highly effective against molecular subgroups of multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BIM PROTEIN; HETERODIMER; NAVITOCLAX; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; PUMA PROTEIN;

EID: 80053653073     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-11-317438     Document Type: Article
Times cited : (102)

References (34)
  • 1
    • 34748924281 scopus 로고    scopus 로고
    • Bcl-2-regulated apoptosis: mechanism and therapeutic potential
    • DOI 10.1016/j.coi.2007.05.004, PII S0952791507000994, Hematopoietic cell death/Immunogenetics/Transplantation
    • Adams JM, Cory S. Bcl-2-regulated apoptosis: mechanism and therapeutical potential. Curr Opin Immunol. 2007;19(5):488-496. (Pubitemid 47487452)
    • (2007) Current Opinion in Immunology , vol.19 , Issue.5 , pp. 488-496
    • Adams, J.M.1    Cory, S.2
  • 3
    • 22044440425 scopus 로고    scopus 로고
    • Cyclin D dysregulation: An early and unifying pathogenic event in multiple myeloma
    • DOI 10.1182/blood-2005-01-0034
    • Bergsagel PL, Kuehl WM, Zhan F, Sawyer J, Barlogie B, Shaughnessy J Jr. Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma. Blood. 2005;106(1):296-303. (Pubitemid 40967205)
    • (2005) Blood , vol.106 , Issue.1 , pp. 296-303
    • Bergsagel, P.L.1    Kuehl, W.M.2    Zhan, F.3    Sawyer, J.4    Barlogie, B.5    Shaughnessy Jr., J.6
  • 4
    • 74049162897 scopus 로고    scopus 로고
    • International Myeloma Working Group molecular classification of multiple myeloma: Spotlight review
    • Fonseca R, Bergsagel PL, Drach J, et al. International Myeloma Working Group molecular classification of multiple myeloma: spotlight review. Leukemia. 2009;23(12):2210-2221.
    • (2009) Leukemia , vol.23 , Issue.12 , pp. 2210-2221
    • Fonseca, R.1    Bergsagel, P.L.2    Drach, J.3
  • 7
    • 0037085778 scopus 로고    scopus 로고
    • Myeloid cell factor-1 is a critical survival factor for multiple myeloma
    • DOI 10.1182/blood.V99.6.1885
    • Zhang B, Gojo I, Fenton RG. Myeloid cell factor-1 is a critical survival factor for multiple myeloma. Blood. 2002;99(6):1885-1893. (Pubitemid 34525465)
    • (2002) Blood , vol.99 , Issue.6 , pp. 1885-1893
    • Zhang, B.1    Gojo, I.2    Fenton, R.G.3
  • 9
    • 78650012656 scopus 로고    scopus 로고
    • BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma
    • Bodet L, Ménoret E, Descamps G, et al. BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma. Br J Cancer. 2010;103(12):1808-1814.
    • (2010) Br J Cancer. , vol.103 , Issue.12 , pp. 1808-1814
    • Bodet, L.1    Ménoret, E.2    Descamps, G.3
  • 10
    • 79953892192 scopus 로고    scopus 로고
    • Human myeloma cell lines (HMCLs) reflect the molecular diversity of primary myeloma cells
    • Moreaux J, Klein B, Bataille R, et al. Human myeloma cell lines (HMCLs) reflect the molecular diversity of primary myeloma cells. Haematologica. 2011;96(4):574-582.
    • (2011) Haematologica. , vol.96 , Issue.4 , pp. 574-582
    • Moreaux, J.1    Klein, B.2    Bataille, R.3
  • 12
    • 33845994359 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
    • DOI 10.1172/JCI28281
    • Del Gaizo Moore V, Brown JR, Certo M, Love TM, Novina CD, Letai A. Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737. J Clin Invest. 2007;117(1):112-121. (Pubitemid 46048458)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.1 , pp. 112-121
    • Moore, V.D.G.1    Brown, J.R.2    Certo, M.3    Love, T.M.4    Novina, C.D.5    Letai, A.6
  • 14
    • 43549125507 scopus 로고    scopus 로고
    • A new method for class prediction based on signed-rank algorithms applied to Affymetrix microarray experiments
    • Rème T, Hose D, De Vos J, et al. A new method for class prediction based on signed-rank algorithms applied to Affymetrix microarray experiments. BMC Bioinformatics. 2008;9:16-28.
    • (2008) BMC Bioinformatics. , vol.9 , pp. 16-28
    • Rème, T.1    Hose, D.2    De Vos, J.3
  • 15
    • 78149360806 scopus 로고    scopus 로고
    • Amazonia!: An online resource to Google and visualize public human whole genome expression data
    • Le Carrour T, Assou S, Tondeur S, et al. Amazonia!: an online resource to Google and visualize public human whole genome expression data. Open Bioinformatics J. 2010;4:5-10.
    • (2010) Open Bioinformatics J. , vol.4 , pp. 5-10
    • Le Carrour, T.1    Assou, S.2    Tondeur, S.3
  • 16
    • 34547603628 scopus 로고    scopus 로고
    • BH3 Profiling Identifies Three Distinct Classes of Apoptotic Blocks to Predict Response to ABT-737 and Conventional Chemotherapeutic Agents
    • DOI 10.1016/j.ccr.2007.07.001, PII S1535610807002000
    • Deng J, Carlson N, Takeyama K, Dal Cin P, Shipp M, Letai A. BH3 profiling identifies three distinct classes of apoptotic blocks to predict response toABT-737 and conventional chemotherapeutic agents. Cancer Cell. 2007;12(2):171-185. (Pubitemid 47199122)
    • (2007) Cancer Cell , vol.12 , Issue.2 , pp. 171-185
    • Deng, J.1    Carlson, N.2    Takeyama, K.3    Dal, C.P.4    Shipp, M.5    Letai, A.6
  • 18
    • 33847061737 scopus 로고    scopus 로고
    • Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737
    • Tahir SK, Yang X, Anderson MG, et al. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. Cancer Res. 2007;67(3):1176-1183.
    • (2007) Cancer Res. , vol.67 , Issue.3 , pp. 1176-1183
    • Tahir, S.K.1    Yang, X.2    Anderson, M.G.3
  • 19
    • 33646354381 scopus 로고    scopus 로고
    • Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
    • DOI 10.1016/j.ccr.2006.03.027, PII S1535610806001139
    • Certo M, Del Gaizo Moore V, Nishino M, et al. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. Cancer Cell. 2006;9(5):351-365. (Pubitemid 43668734)
    • (2006) Cancer Cell , vol.9 , Issue.5 , pp. 351-365
    • Certo, M.1    Moore, V.D.G.2    Nishino, M.3    Wei, G.4    Korsmeyer, S.5    Armstrong, S.A.6    Letai, A.7
  • 20
    • 68149112387 scopus 로고    scopus 로고
    • Mimicking the BH3 domain to kill cancer cells
    • Chonghaile TN, Letai A. Mimicking the BH3 domain to kill cancer cells. Oncogene. 2008;27(suppl 1):S149-S157.
    • (2008) Oncogene , vol.27 , Issue.SUPPL. 1
    • Chonghaile, T.N.1    Letai, A.2
  • 22
    • 65349152495 scopus 로고    scopus 로고
    • Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members
    • Gallenne T, Gautier F, Oliver L, et al. Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members. J Cell Biol. 2009;185(2):279-290.
    • (2009) J Cell Biol. , vol.185 , Issue.2 , pp. 279-290
    • Gallenne, T.1    Gautier, F.2    Oliver, L.3
  • 24
    • 41349123507 scopus 로고    scopus 로고
    • BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia
    • DOI 10.1182/blood-2007-06-098012
    • Del Gaizo Moore V, Schlis KD, Sallan SE, Armstrong SA, Letai A. BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia. Blood. 2008;111(4):2300-2309. (Pubitemid 351451437)
    • (2008) Blood , vol.111 , Issue.4 , pp. 2300-2309
    • Del, G.M.V.1    Schlis, K.D.2    Sallan, S.E.3    Armstrong, S.A.4    Letai, A.5
  • 27
    • 34250770481 scopus 로고    scopus 로고
    • ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells
    • DOI 10.1038/sj.leu.2404719, PII 2404719
    • Kline MP, Rajkumar SV, Timm MM, et al. ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells. Leukemia. 2007;21(7):1549-1560. (Pubitemid 46965297)
    • (2007) Leukemia , vol.21 , Issue.7 , pp. 1549-1560
    • Kline, M.P.1    Rajkumar, S.V.2    Timm, M.M.3    Kimlinger, T.K.4    Haug, J.L.5    Lust, J.A.6    Greipp, P.R.7    Kumar, S.8
  • 28
  • 29
    • 34248180714 scopus 로고    scopus 로고
    • Integrative genomic analysis of small-cell lung carcinoma reveals correlates of sensitivity to Bcl-2 antagonists and uncovers novel chromosomal gains
    • DOI 10.1158/1541-7786.MCR-06-0367
    • Olejniczak ET, Van Sant C, Anderson MG, et al. Integrative genomic analysis of small-cell lung carcinoma reveals correlates of sensitivity to bcl-2 antagonists and uncovers novel chromosomal gains. Mol Cancer Res. 2007;5(4):331-339. (Pubitemid 46706995)
    • (2007) Molecular Cancer Research , vol.5 , Issue.4 , pp. 331-339
    • Olejniczak, E.T.1    Van Sant, C.2    Anderson, M.G.3    Wang, G.4    Tahir, S.K.5    Sauter, G.6    Lesniewski, R.7    Semizarov, D.8
  • 30
    • 77953632707 scopus 로고    scopus 로고
    • Superior results of Total Therapy 3 (2003-33) in gene expression profiling-defined low-risk multiple myeloma confirmed in subsequent trial 2006-66 with VRD maintenance
    • Nair B, Van Rhee F, Shaughnessy JD Jr, et al. Superior results of Total Therapy 3 (2003-33) in gene expression profiling-defined low-risk multiple myeloma confirmed in subsequent trial 2006-66 with VRD maintenance. Blood. 2010;115(21):4168-4173.
    • (2010) Blood , vol.115 , Issue.21 , pp. 4168-4173
    • Nair, B.1    Van Rhee, F.2    Shaughnessy Jr., J.D.3
  • 31
    • 44849112219 scopus 로고    scopus 로고
    • ABT-263: A potent and orally bioavailable Bcl-2 family inhibitor
    • Tse C, Shoemaker AR, Adickes J, et al. ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor. Cancer Res. 2008;68(9):3421-3428.
    • (2008) Cancer Res. , vol.68 , Issue.9 , pp. 3421-3428
    • Tse, C.1    Shoemaker, A.R.2    Adickes, J.3
  • 32
    • 79952291173 scopus 로고    scopus 로고
    • Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors
    • Gandhi L, Camidge DR, Ribeiro de Oliveira M, et al. Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors. J Clin Oncol. 2011;29(7):909-916.
    • (2011) J Clin Oncol. , vol.29 , Issue.7 , pp. 909-916
    • Gandhi, L.1    Camidge, D.R.2    Ribeiro De Oliveira, M.3
  • 33
    • 70350634322 scopus 로고    scopus 로고
    • An ongoing phase & study of ABT-263; pharmacokinetics, safety and anti-tumor activity in patients with relapsed or refractory chronic lymphocytic leukemia
    • abstract. Abstract 3177
    • Roberts AW, Brown J, Seymour JF, et al. An ongoing phase & study of ABT-263; pharmacokinetics, safety and anti-tumor activity in patients with relapsed or refractory chronic lymphocytic leukemia [abstract]. Blood. 2008;112: Abstract 3177.
    • (2008) Blood , pp. 112
    • Roberts, A.W.1    Brown, J.2    Seymour, J.F.3
  • 34
    • 59349109256 scopus 로고    scopus 로고
    • A phase 1 study evaluating the safety, pharmacokinetics, and efficacy of ABT-263 in subjects with refractory or relapsed lymphoid malignancies
    • [abstract]. Abstract 8511
    • Wilson WH, Czuczman MS, LaCasce AS, et al. A phase 1 study evaluating the safety, pharmacokinetics, and efficacy of ABT-263 in subjects with refractory or relapsed lymphoid malignancies [abstract]. J Clin Oncol. 2008;26: Abstract 8511.
    • (2008) J Clin Oncol. , pp. 26
    • Wilson, W.H.1    Czuczman, M.S.2    LaCasce, A.S.3


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