Neurturin evokes MAPK-dependent upregulation of Egr4 and KCC2 in developing neurons

Neural Plasticity

Volumn 2011, Issue , 2011, Pages

  Rivera, Claudio ^a,b,d,e   Ludwig, Anastasia ^a,b   Uvarov, Pavel ^a   Pellegrino, Christophe ^a,c,d,e   Thomas Crusells, Judith ^b   Schuchmann, Sebastian ^f   Saarma, Mart ^b   Airaksinen, Matti S ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c INSERM   (France)

^d AIX MARSEILLE UNIVERSITY   (France)

^e Turing Center for Living Systems CENTURI Aix Marseille University   (France)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; EARLY GROWTH RESPONSE FACTOR; EARLY GROWTH RESPONSE FACTOR 4; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEURTURIN; POTASSIUM CHLORIDE COTRANSPORTER; POTASSIUM CHLORIDE COTRANSPORTER 2; UNCLASSIFIED DRUG; COTRANSPORTER; EGR4 PROTEIN, MOUSE; POTASSIUM-CHLORIDE SYMPORTERS;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; FEMALE; INTRACELLULAR SIGNALING; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; COMPARATIVE STUDY; HIPPOCAMPUS; METABOLISM; NERVE CELL; NEWBORN; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; EARLY GROWTH RESPONSE TRANSCRIPTION FACTORS; HIPPOCAMPUS; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; NEURTURIN; ORGAN CULTURE TECHNIQUES; SYMPORTERS; UP-REGULATION;

EID: 80053643920     PISSN: 20905904     EISSN: 16875443     Source Type: Journal    
DOI: 10.1155/2011/641248     Document Type: Article

References (21)

1. Blaesse P., Airaksinen M. S., Rivera C., Kaila K., Cation-chloride cotransporters and neuronal function Neuron 2009 61 6 820 838
2. Rivera C., Voipio J., Thomas-Crusells J., Li H., Emri Z., Sipil S., Payne J. A., Minichiello L., Saarma M., Kaila K., Mechanism of activity-dependent downregulation of the neuron-specific K-Cl cotransporter KCC2 Journal of Neuroscience 2004 24 19 4683 4691 (Pubitemid 38656623)
3. Ludwig A., Uvarov P., Soni S., Thomas-Crusells J., Airaksinen M. S., Rivera C., Early growth response 4 mediates BDNF induction of potassium chloride cotransporter 2 transcription Journal of Neuroscience 2011 31 2 644 649
4. Rivera C., Li H., Thomas-Crusells J., Lahtinen H., Viitanen T., Nanobashvili A., Kokaia Z., Airaksinen M. S., Voipio J., Kaila K., Saarma M., BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion Journal of Cell Biology 2002 159 5 747 752 (Pubitemid 36008357)
5. Huang E. J., Reichardt L. F., Trk receptors: roles in neuronal signal transduction Annual Review of Biochemistry 2003 72 609 642 (Pubitemid 36930455)
6. Reichardt L. F., Neurotrophin-regulated signalling pathways Philosophical Transactions of the Royal Society B 2006 361 1473 1545 1564 (Pubitemid 44450210)
7. Yoshii A., Constantine-Paton M., Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease Developmental Neurobiology 2010 70 5 304 322
8. Frost D. O., BDNF/trkB signaling in the developmental sculpting of visual connections Progress in Brain Research 2001 134 35 49
9. Airaksinen M. S., Saarma M., The GDNF family: signalling, biological functions and therapeutic value Nature Reviews Neuroscience 2002 3 5 383 394 (Pubitemid 135706635)
10. Banker G., Goslin K., Culturing Nerve Cells 1998 Cambridge, Mass, USA The MIT Press
11. Stoppini L., Buchs P. A., Muller D., A simple method for organotypic cultures of nervous tissue Journal of Neuroscience Methods 1991 37 2 173 182
12. Ludwig A., Li H., Saarma M., Kaila K., Rivera C., Developmental up-regulation of KCC2 in the absence of GABAergic and glutamatergic transmission European Journal of Neuroscience 2003 18 12 3199 3206 (Pubitemid 38031046)
13. Li H., Tornberg J., Kaila K., Airaksinen M. S., Rivera C., Patterns of cation-chloride cotransporter expression during embryonic rodent CNS development European Journal of Neuroscience 2002 16 12 2358 2370 (Pubitemid 36056960)
14. Kokaia Z., Airaksinen M. S., Nanobashvili A., GDNF family ligands and receptors are differentially regulated after brain insults in the rat European Journal of Neuroscience 1999 11 4 1202 1216 (Pubitemid 29142180)
15. Kotzbauer P. T., Lampe P. A., Heuckeroth R. O., Golden J. P., Creedon D. J., Johnson E. M. Jr., Milbrandt J., Neurturin, a relative of glial-cell-line-derived neurotrophic factor Nature 1996 384 6608 467 470 (Pubitemid 26414664)
16. Uvarov P., Ludwig A., Markkanen M., Rivera C., Airaksinen M. S., Upregulation of the neuron-specific K+/Cl- cotransporter expression by transcription factor early growth response 4 Journal of Neuroscience 2006 26 52 13463 13473 (Pubitemid 46026478)
17. Ivanova T., Beyer C., Pre- and postnatal expression of brain-derived neurotrophic factor mRNA/protein and tyrosine protein kinase receptor B mRNA in the mouse hippocampus Neuroscience Letters 2001 307 1 21 24 (Pubitemid 32539299)
18. Lenhard T., Suter-Crazzolara C., Developmental expression of GDNF, neurturin and their receptors in rat hippocampus NeuroReport 1998 9 13 2927 2931 (Pubitemid 28555622)
19. Burazin T. C. D., Gundlach A. L., Localization of GDNF/neurturin receptor (c-ret, GFR -1 and -2) mRNAs in postnatal rat brain: differential regional and temporal expression in hippocampus, cortex and cerebellum Molecular Brain Research 1999 73 1-2 151 171
20. Ludwig A., Mechanisms of KCC2 Up-Regulation during Development 2008 Helsinki, Finland University of Helsinki, Institute of Biotechnology Department of Biological and Environmental Sciences
21. Sariola H., Saarma M., Novel functions and signalling pathways for GDNF Journal of Cell Science 2003 116 19 3855 3862 (Pubitemid 37279301)