Comparison of germinal center markers CD10, BCL6 and human germinal center-associated lymphoma (HGAL) in follicular lymphomas

Diagnostic Pathology

Volumn 6, Issue 1, 2011, Pages

  Goteri, Gaia ^a   Lucarini, Guendalina ^a   Zizzi, Antonio ^a   Costagliola, Antonello ^a   Giantomassi, Federica ^a   Stramazzotti, Daniela ^a   Rubini, Corrado ^a   Leoni, Pietro ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BCL6 PROTEIN, HUMAN; DNA BINDING PROTEIN; GCET2 PROTEIN, HUMAN; MEMBRANE METALLOENDOPEPTIDASE; TUMOR MARKER; TUMOR PROTEIN;

ADULT; AGED; ARTICLE; BIOSYNTHESIS; COMPARATIVE STUDY; FOLLICULAR LYMPHOMA; GERMINAL CENTER; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; MIDDLE AGED; PATHOLOGY; POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; DNA-BINDING PROTEINS; GERMINAL CENTER; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOMA, FOLLICULAR; MIDDLE AGED; NEOPLASM PROTEINS; NEPRILYSIN; POLYMERASE CHAIN REACTION; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 80053635047     PISSN: None     EISSN: 17461596     Source Type: Journal    
DOI: 10.1186/1746-1596-6-97     Document Type: Article

References (29)

1. Anderson JR, Armitage JO, Weisenburger DD. Epidemiology of the non-Hodgkin's lymphomas: distributions of the major subtypes differ by geographic locations. Non-Hodgkin's lymphoma classification project. Ann Oncol 1998, 9:717-720. 10.1023/A:1008265532487, 9739436.
2. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues 2008, Lyon France: IARC Press.
3. Cong P, Raffeld M, Teruya-Feldstein J, Sorbara L, Pittaluga S, Jaffe ES. In situ localization of follicular lymphoma: description and analysis by laser capture microdissection. Blood 2002, 99:3376-3382. 10.1182/blood.V99.9.3376, 11964306.
4. Younes SF, Beck AH, Lossos IS, Levy R, Warnke RA, Natkunam Y. Immunoarchitectural pattern in follicular lymphoma: efficacy of HGAL and LMO2 in the detection of interfollicular and diffuse components. Am J Surg Pathol 2010, 34:1266-1276. 10.1097/PAS.0b013e3181e9343d, 2929284, 20697248.
5. Rowley JD. Chromosome studies in the non-Hodgkin's lymphomas: the role of the 14;18 translocation. J Clin Oncol 1988, 6:919-925.
6. Horsman DE, Gascoyne RD, Coupland RW, Coldman AJ, Adomat SA. Comparison of cytogenetic analysis, Southern analysis, and polymerase chain reaction for the detection of t(14; 18) in follicular lymphoma. Am J Clin Pathol 1995, 103:472-478.
7. Gu K, Chan WC, Hawley RC. Practical detection of t(14;18)(IGH@/BCL2) in follicular lymphoma. Arch Pathol Lab Med 2008, 132:1355-1361.
8. Cleary ML, Sklar J. Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci USA 1985, 82:7439-7443. 10.1073/pnas.82.21.7439, 391360, 2865728.
9. Cleary ML, Galili N, Sklar J. Detection of a second t(14;18) breakpoint cluster region in human follicular lymphomas. J Exp Med 1986, 164:315-320. 10.1084/jem.164.1.315, 2188210, 3014037.
10. Tsujimoto Y, Bashir MM, Givol I, Cossman J, Jaffe E, Croce CM. DNA rearrangements in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene. Proc Natl Acad Sci USA 1987, 84:1329-1331. 10.1073/pnas.84.5.1329, 304421, 3547408.
11. Merup M, Spasokoukotskaja T, Einhorn S, Smith CI, Gahrton G, Juliusson G. Bcl-2 rearrangements with breakpoints in both vcr and mbr in non-Hodgkin's lymphomas and chronic lymphocytic leukaemia. Br J Haematol 1996, 92:647-652. 10.1046/j.1365-2141.1996.00388.x, 8616030.
12. Albinger-Hegyi A, Hochreutener B, Abdou MT, Hegyi I, Dours-Zimmermann MT, Kurrer MO, Heitz PU, Zimmermann DR. High frequency of t(14;18)-translocation breakpoints outside of major breakpoint and minor cluster regions in follicular lymphomas: improved polymerase chain reaction protocols for their detection. Am J Pathol 2002, 160:823-832. 10.1016/S0002-9440(10)64905-X, 1867177, 11891181.
13. Ott G, Rosenwald A. Molecular pathogenesis of follicular lymphoma. Haematologica 2008, 93:1773-1776. 10.3324/haematol.2008.001495, 19050067.
14. Roulland S, Navarro JM, Grenot P, Milili M, Agopian J, Montpellier B, Gauduchon P, Lebailly P, Schiff C, Nadel B. Follicular lymphoma-like B cells in healthy individuals: a novel intermediate step in early lymphomagenesis. J Exp Med 2006, 203:2425-2431. 10.1084/jem.20061292, 2118129, 17043145.
15. Lossos IS, Alizadeh AA, Rajapaksa R, Tibshirani R, Levy R. HGAL is a novel interleukin-4-inducible gene that strongly predicts survival in diffuse large B-cell lymphoma. Blood 2003, 101:433-440. 10.1182/blood-2002-06-1931, 12509382.
16. Natkunam Y, Lossos IS, Taidi B, Zhao S, Lu X, Ding F, Hammer AS, Marafioti T, Byrne GE, Levy S, Warnke RA, Levy R. Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation. Blood 2005, 105:3979-3986. 10.1182/blood-2004-08-3112, 1895083, 15677569.
17. Xie X, Sundram U, Natkunam Y, Kohler S, Hoppe RT, Kim YH, Cook JR, Hammel J, Swerdlow SH, Guitart J, Smith MD, Bosler D, Listinsky C, Lossos IS, Hsi ED. Expression of HGAL in primary cutaneous large B-cell lymphomas: evidence for germinal center derivation of primary cutaneous follicular lymphoma. Mod Pathol 2008, 21:653-659. 10.1038/modpathol.2008.30, 18264083.
18. Diss TC, Pan L, Peng H, Wotherspoon AC, Isaacson PG. Sources of DNA for detecting B cell monoclonality using PCR. J Clin Pathol 1994, 47:493-496. 10.1136/jcp.47.6.493, 494724, 8063927.
19. Leone PE, Pérez JC, Morillo SA, Paz-y-Miño C. Low incidence of follicular lymphoma and t(14;18)(q32;q21) by polymerase chain reaction analysis. Observations on Ecuadorian patients. Cancer Genet Cytogenet 2002, 37:72-74.
20. Einerson RR, Kurtin PJ, Dayharsh GA, Kimlinger TK, Remstein ED. FISH is superior to PCR in detecting t(14;18)(q32;q21)-IGH@/bcl-2 in follicular lymphoma using paraffin-embedded tissue samples. Am J Clin Pathol 2005, 124:421-429. 10.1309/BLH8MMK85UBQ4K6R, 16191511.
21. Weinberg OK, Ma L, Seo K, Beck AH, Pai RK, Morales A, Kim Y, Sundram U, Tan D, Horning SJ, Hoppe RT, Natkunam Y, Arber DA. Low stage follicular lymphoma: biologic and clinical characterization according to nodal or extranodal primary origin. Am J Surg Pathol 2009, 33:591-598. 10.1097/PAS.0b013e31818e6489, 19065102.
22. Dogan A, Bagdi E, Munson P, Isaacson PG. CD10 and BCL-6 expression in paraffin sections of normal lymphoid tissue and B-cell lymphoma. Am J Surg Pathol 2000, 24:846-852. 10.1097/00000478-200006000-00010, 10843287.
23. Eshoa C, Perkins S, Kampalath B, Shidham V, Juckett M, Chang CC. Decreased CD10 expression in grade III and in interfollicular infiltrates of follicular lymphomas. Am J Clin Pathol 2001, 115:862-867. 10.1309/B6MK-J7NF-A6JP-X56K, 11392883.
24. Bosga-Bouwer AG, van den Berg A, Haralambieva E, de Jong D, Boonstra R, Kluin P, van den Berg E, Poppema S. Molecular, cytogenetic, and immunophenotypic characterization of follicular lymphoma grade 3B; a separate entity or part of the spectrum of diffuse large B-cell lymphoma or follicular lymphoma?. Hum Pathol 2006, 37:528-533. 10.1016/j.humpath.2005.12.005, 16647949.
25. Cattoretti G, Chang CC, Cechova K, Zhang J, Ye BH, Falini B, Louie DC, Offit K, Chaganti RS, Dalla-Favera R. BCL-6 protein is expressed in germinal-center B-cells. Blood 1995, 86:45-53.
26. Salama ME, Lossos IS, Warnke RA, Natkunam Y. Immunoarchitectural Patterns in Nodal Marginal Zone B-Cell Lymphoma. A Study of 51 Cases. Am J Clin Pathol 2009, 132:39-49. 10.1309/AJCPZQ1GXBBNG8OG, 2894708, 19864232.
27. Falini B, Tiacci E, Pucciarini A, Bigerna B, Kurth J, Hatzivassiliou G, Droetto S, Galletti BV, Gambacorta M, Orazi A, Pasqualucci L, Miller I, Kuppers R, Dalla-Favera R, Cattoretti G. Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT). Blood 2003, 102:3684-3692. 10.1182/blood-2003-03-0750, 12881317.
28. Went P, Ascani S, Strøm E, Brorson SH, Musso M, Zinzani PL, Falini B, Dirnhofer S, Pileri S. Nodal marginal-zone lymphoma associated with monoclonal light-chain and heavy-chain deposition disease. Lancet Oncol 2004, 5:381-383. 10.1016/S1470-2045(04)01495-0, 15172359.
29. Natkunam Y, Zhao S, Mason DY, Chen J, Taidi B, Jones M, Hammer AS, Hamilton Dutoit S, Lossos IS, Levy R. The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas. Blood 2007, 109:1636-1642. 10.1182/blood-2006-08-039024, 1794056, 17038524.