Drosophila highwire gene modulates acute ethanol sensitivity in the nervous system

Frontiers in Biology

Volumn 6, Issue 5, 2011, Pages 414-421

  Awofala, Awoyemi A ^a,b  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b TAI SOLARIN UNIVERSITY OF EDUCATION   (Nigeria)

Author keywords

Drosophila; ellipsoid body; ethanol sensitivity; hiw; neurons; ubiquitin ligase

Indexed keywords

ANIMALIA;

EID: 80053628312     PISSN: 16747984     EISSN: 16747992     Source Type: Journal    
DOI: 10.1007/s11515-011-1144-4     Document Type: Article

References (25)

1. Berger K H, Heberlein U, Moore M S (2004). Rapid and chronic: two distinct forms of ethanol tolerance in Drosophila. Alcohol Clin Exp Res, 28(10): 1469-1480.
2. Cheng Y, Endo K, Wu K, Rodan A R, Heberlein U, Davis R L (2001). Drosophila fasciclinII is required for the formation of odor memories and for normal sensitivity to alcohol. Cell, 105(6): 757-768.
3. Collins C A, Wairkar Y P, Johnson S L, DiAntonio A (2006). Highwire restrains synaptic growth by attenuating a MAP kinase signal. Neuron, 51(1): 57-59.
4. DiAntonio A, Haghighi A P, Portman S L, Lee J D, Amaranto A M, Goodman C S (2001). Ubiquitination-dependent mechanisms regulate synaptic growth and function. Nature, 412(6845): 449-452.
5. Han S, Witt R M, Santos T M, Polizzano C, Sabatini B L, Ramesh V (2008). Pam (Protein associated with Myc) functions as an E3 ubiquitin ligase and regulates TSC/mTOR signaling. Cell Signal, 20(6): 1084-1091.
6. Hiraishi H, Okada M, Ohtsu I, Takagi H (2009). A functional analysis of the yeast ubiquitin ligase Rsp5: the involvement of the ubiquitin-conjugating enzyme Ubc4 and poly-ubiquitination in ethanolinduced down-regulation of targeted proteins. Biosci Biotechnol Biochem, 73(10): 2268-2273.
7. McCabe B D, Hom S, Aberle H, Fetter R D, Marques G, Haerry T E, Wan H, O'Connor M B, Goodman C S, Haghighi A P (2004). Highwire regulates presynaptic BMP signaling essential for synaptic growth. Neuron, 41(6): 891-905.
8. Miguel-Hidalgo J J (2009). The role of glial cells in drug abuse. Curr Drug Abuse Rev, 2(1): 76-82.
9. Moore M S, DeZazzo J, Luk A Y, Tully T, Singh C M, Heberlein U (1998). Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway. Cell, 93(6): 997-9007.
10. Nakata K, Abrams B, Grill B, Goncharov A, Huang X, Chisholm A D, Jin Y (2005). Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development. Cell, 120(3): 407-420.
11. Pan Y, Zhou Y, Guo C, Gong H, Gong Z, Liu L (2009). Differential roles of the fan-shaped body and the ellipsoid body in Drosophila visual pattern memory. Learn Mem, 16(5): 289-295.
12. Pierre S C, Häusler J, Birod K, Geisslinger G, Scholich K (2004). PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate. EMBO J, 23(15): 3031-3040.
13. Renn S C P, Armstrong J D, Yang M, Wang Z, An X, Kaiser K, Taghert P H (1999). Genetic analysis of the Drosophila ellipsoid body neuropil: organization and development of the central complex. J Neurobiol, 41(2): 189-207.
14. Rodan A R, Kiger J A Jr, Heberlein U (2002). Functional dissection of neuroanatomical loci regulating ethanol sensitivity in Drosophila. J Neurosci, 22(21): 9490-9501.
15. Schuckit M A, Gold E O (1988). A simultaneous evaluation of multiple markers of ethanol/placebo challenges in sons of alcoholics and controls. Arch Gen Psychiatry, 45(3): 211-216.
16. Schuckit M A, Tsuang J W, Anthenelli R M, Tipp J E, Nurnberger J I Jr (1996). Alcohol challenges in young men from alcoholic pedigrees and control families: a report from the COGA project. J Stud Alcohol, 57(4): 368-377.
17. Sharma P, Asztalos Z, Ayyub C, de Bruyne M, Dornan A J, Gomez-Hernandez A, Keane J, Killeen J, Kramer S, Madhavan M, Roe H, Sherkhane P D, Siddiqi K, Silva E, Carlson J R, Goodwin S F, Heisenberg M, Krishnan K, Kyriacou C P, Partridge L, Riesgo-Escovar J, Rodrigues V, Tully T, O'Kane C J (2005). Isogenic autosomes to be applied in optimal screening for novel mutants with viable phenotypes in Drosophila melanogaster. J Neurogenet, 19(2): 57-85.
18. Urizar N L, Yang Z, Edenberg H J, Davis R L (2007). Drosophila homer is required in a small set of neurons including the ellipsoid body for normal ethanol sensitivity and tolerance. J Neurosci, 27(17): 4541-4551.
19. Wan H I, DiAntonio A, Fetter R D, Bergstrom K, Strauss R, Goodman C S (2000). Highwire regulates synaptic growth in Drosophila. Neuron, 26(2): 313-329.
20. Wand G, Levine M, Zweifel L, Schwindinger W, Abel T (2001). The cAMP-protein kinase A signal transduction pathway modulates ethanol consumption and sedative effects of ethanol. J Neurosci, 21: 5297-5303.
21. Wen T, Parrish C A, Xu D, Wu Q, Shen P (2005). Drosophila neuropeptide F and its receptor, NPFR1, define a signaling pathway that acutely modulates alcohol sensitivity. Proc Natl Acad Sci USA, 102(6): 2141-2146.
22. Wolf F W, Heberlein U (2003). Invertebrate models of drug abuse. J Neurobiol, 54(1): 161-178.
23. Wu C, Wairkar Y P, Collins C A, DiAntonio A (2005). Highwire function at the Drosophila neuromuscular junction: spatial, structural, and temporal requirements. J Neurosci, 25(42): 9557-9566.
24. Wu C L, Xia S, Fu T F, Wang H, Chen Y H, Leong D, Chiang A S, Tully T (2007). Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body. Nat Neurosci, 10(12): 1578-1586.
25. Yamamoto M, Pohli S, Durany N, Ozawa H, Saito T, Boissl K W, Zöchling R, Riederer P, Böning J, Götz M E (2001). Increased levels of calcium-sensitive adenylyl cyclase subtypes in the limbic system of alcoholics: evidence for a specific role of cAMP signaling in the human addictive brain. Brain Res, 895(1-2): 233-237.