The effect of age and tongue exercise on BDNF and TrkB in the hypoglossal nucleus of rats

Behavioural Brain Research

Volumn 226, Issue 1, 2012, Pages 235-241

  Schaser, Allison J ^a,b   Stang, Kyle ^c   Connor, Nadine P ^a,b   Behan, Mary ^c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Aging; Exercise; Hypoglossal nucleus; Neurotrophic factors; Swallowing; Tongue muscle

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; NEUROTROPIN;

AGE DISTRIBUTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DYSPHAGIA; EXERCISE; GROUPS BY AGE; HYPOGLOSSAL NUCLEUS; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MUSCLE FORCE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SENSORIMOTOR FUNCTION; TONGUE;

AGE FACTORS; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; MALE; MEDULLA OBLONGATA; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, INBRED F344; RECEPTOR, TRKB; TONGUE;

EID: 80053611704     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.09.027     Document Type: Article

References (52)

1. Rosenberg I.H., Sarcopenia Origins and clinical relevance. J Nutr 1997, 127(May (5 Suppl)):990S-991S.
2. Doherty T.J. Invited review: aging and sarcopenia. J Appl Physiol 2003, 95(October (4)):1717-1727.
3. Janssen I. Evolution of sarcopenia research. Appl Physiol Nutr Metab 2010, 35(October (5)):707-712.
4. Roubenoff R. Origins and clinical relevance of sarcopenia. Can J Appl Physiol 2001, 26(February (1)):78-89.
5. Marcell T.J., Sarcopenia Causes, consequences, and preventions. J Gerontol A Biol Sci Med Sci 2003, 58(October (10)):M911-M916.
6. Thomas D.R. Sarcopenia. Clin Geriatr Med 2010, 26(May (2)):331-346.
7. Dutta C. Significance of sarcopenia in the elderly. J Nutr 1997, 127(May (5 Suppl)):992S-993S.
8. Lang T., Streeper T., Cawthon P., Baldwin K., Taaffe D.R., Harris T.B., et al. Etiology, clinical consequences, intervention, and assessment. Osteoporos Int 2010, 21(April (4)):543-559.
9. Connor N.P., Russell J.A., Wang H., Jackson M.A., Mann L., Kluender K. Effect of tongue exercise on protrusive force and muscle fiber area in aging rats. J Speech Lang Hear Res 2009, 52(June (3)):732-744.
10. Johnson A.M., Connor N.P. Effects of electrical stimulation on neuromuscular junction morphology in the aging rat tongue. Muscle Nerve 2011, 43(February (2)):203-211.
11. Schaser A.J., Wang H., Volz L.M., Connor N.P. Biochemistry of the anterior, medial, and posterior genioglossus in the aged rat. Dysphagia 2010, (August).
12. Cook I.J., Weltman M.D., Wallace K., Shaw D.W., McKay E., Smart R.C., et al. Influence of aging on oral-pharyngeal bolus transit and clearance during swallowing: scintigraphic study. Am J Physiol 1994, 266(June (6 Pt 1)):G972-G977.
13. Nicosia M.A., Hind J.A., Roecker E.B., Carnes M., Doyle J., Dengel G.A., et al. Age effects on the temporal evolution of isometric and swallowing pressure. J Gerontol A Biol Sci Med Sci 2000, 55(November (11)):M634-M640.
14. Kirkendall D.T., Garrett W.E. The effects of aging and training on skeletal muscle. Am J Sports Med 1998, 26(July-August (4)):598-602.
15. Liu C.J., Latham N.K. Progressive resistance strength training for improving physical function in older adults. Cochrane Database Syst Rev 2009, 3(July (3)):CD002759.
16. Waters D.L., Baumgartner R.N., Garry P.J., Vellas B. Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update. Clin Interv Aging 2010, 5(September (7)):259-270.
17. Peterson M.D., Sen A., Gordon P.M. Influence of resistance exercise on lean body mass in aging adults: a meta-analysis. Med Sci Sports Exerc 2011, 43(February (2)):249-258.
18. Robbins J., Gangnon R.E., Theis S.M., Kays S.A., Hewitt A.L., Hind J.A. The effects of lingual exercise on swallowing in older adults. J Am Geriatr Soc 2005, 53(September (9)):1483-1489.
19. Kays S., Robbins J. Effects of sensorimotor exercise on swallowing outcomes relative to age and age-related disease. Semin Speech Lang 2006, 27(November (4)):245-259.
20. Logemann J.A. The role of exercise programs for dysphagia patients. Dysphagia 2005, 20(Spring (2)):139-140.
21. Yeates E.M., Molfenter S.M., Steele C.M. Improvements in tongue strength and pressure-generation precision following a tongue-pressure training protocol in older individuals with dysphagia: three case reports. Clin Interv Aging 2008, 3(4):735-747.
22. Mattson M.P. Neuroprotective signaling and the aging brain: take away my food and let me run. Brain Res 2000, 886(December (1-2)):47-53.
23. Smith A.D., Zigmond M.J. Can the brain be protected through exercise? lessons from an animal model of parkinsonism. Exp Neurol 2003, 184(November (1)):31-39.
24. Grondard C., Biondi O., Armand A.S., Lecolle S., Della Gaspera B., Pariset C., et al. Regular exercise prolongs survival in a type 2 spinal muscular atrophy model mouse. J Neurosci 2005, 25(August (33)):7615-7622.
25. Ebadi M., Bashir R.M., Heidrick M.L., Hamada F.M., Refaey H.E., Hamed A., et al. Neurotrophins and their receptors in nerve injury and repair. Neurochem Int 1997, 30(April-May (4-5)):347-374.
26. Schinder A.F., Poo M. The neurotrophin hypothesis for synaptic plasticity. Trends Neurosci 2000, 23(December (12)):639-645.
27. Poo M.M. Neurotrophins as synaptic modulators. Nat Rev Neurosci 2001, 2(January (1)):24-32.
28. Skaper S.D. The biology of neurotrophins, signalling pathways, and functional peptide mimetics of neurotrophins and their receptors. CNS Neurol Disord Drug Targets 2008, 7(February (1)):46-62.
29. Johnson H., Hokfelt T., Ulfhake B. Decreased expression of TrkB and TrkC mRNAs in spinal motoneurons of aged rats. Eur J Neurosci 1996, 8(March (3)):494-499.
30. Yuen E.C., Mobley W.C. Therapeutic applications of neurotrophic factors in disorders of motor neurons and peripheral nerves. Mol Med Today 1995, 1(September (6)):278-286.
31. Lindsay R.M. Therapeutic potential of the neurotrophins and neurotrophin-CNTF combinations in peripheral neuropathies and motor neuron diseases. Ciba Found Symp 1996, 39,48; discussion 48-53.
32. Yuen E.C. The role of neurotrophic factors in disorders of peripheral nerves and motor neurons. Phys Med Rehabil Clin N Am 2001, 12(May (2)). 293,306, viii.
33. Vaynman S., Ying Z., Gomez-Pinilla F. Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity. Neuroscience 2003, 122(3):647-657.
34. Gomez-Pinilla F., Ying Z., Opazo P., Roy R.R., Edgerton V.R. Differential regulation by exercise of BDNF and NT-3 in rat spinal cord and skeletal muscle. Eur J Neurosci 2001, 13(March (6)):1078-1084.
35. Baker-Herman T.L., Fuller D.D., Bavis R.W., Zabka A.G., Golder F.J., Doperalski N.J., et al. BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia. Nat Neurosci 2004, 7(January (1)):48-55.
36. Wilkerson J.E., Mitchell G.S. Daily intermittent hypoxia augments spinal BDNF levels, ERK phosphorylation and respiratory long-term facilitation. Exp Neurol 2009, 217(May (1)):116-123.
37. Turturro A., Witt W.W., Lewis S., Hass B.S., Lipman R.D., Hart R.W. Growth curves and survival characteristics of the animals used in the biomarkers of aging program. J Gerontol A Biol Sci Med Sci 1999, 54(November (11)):B492-B501.
38. Behan M, Moeser AE, Thomas CF, Wang H, Leverson GE, Connor, NP. The effect of tongue exercise on serotonergic input to the hypoglossal nucleus in young and old rats. Program No. 82.7/BB9. 2009 Neuroscience Meeting Planner. Chicago, IL: Society for Neuroscience, 2009. Online.
39. Ciucci M.R., Connor N.P. Dopaminergic influence on rat tongue function and limb movement initiation. Exp Brain Res 2009, 194(April (4)):587-596.
40. Abramoff M.D., Magelhaes P.J., Ram S.J. Image processing with Image. J Biophoton Int 2004, 11(7):36-42.
41. Bothwell M. Functional interactions of neurotrophins and neurotrophin receptors. Annu Rev Neurosci 1995, 18:223-253.
42. Barbacid M. Neurotrophic factors and their receptors. Curr Opin Cell Biol 1995, 7(April (2)):148-155.
43. Bergman E., Johnson H., Zhang X., Hokfelt T., Ulfhake B. Neuropeptides and neurotrophin receptor mRNAs in primary sensory neurons of aged rats. J Comp Neurol 1996, 375(November (2)):303-319.
44. Johnson H., Hokfelt T., Ulfhake B. Expression of p75(NTR), trkB and trkC in nonmanipulated and axotomized motoneurons of aged rats. Brain Res Mol Brain Res 1999, 69(May (1)):21-34.
45. Rage F., Silhol M., Biname F., Arancibia S., Tapia-Arancibia L. Effect of aging on the expression of BDNF and TrkB isoforms in rat pituitary. Neurobiol Aging 2007, 28(July (7)):1088-1098.
46. Patapoutian A., Reichardt L.F. Trk receptors: mediators of neurotrophin action. Curr Opin Neurobiol 2001, 11(June (3)):272-280.
47. Funakoshi H., Belluardo N., Arenas E., Yamamoto Y., Casabona A., Persson H., et al. Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. Science 1995, 268(June (5216)):1495-1499.
48. Friedman B., Kleinfeld D., Ip N.Y., Verge V.M., Moulton R., Boland P., et al. BDNF and NT-4/5 exert neurotrophic influences on injured adult spinal motor neurons. J Neurosci 1995, 15(February (2)):1044-1056.
49. Jakeman L.B., Wei P., Guan Z., Stokes B.T. Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury. Exp Neurol 1998, 154(November (1)):170-184.
50. Zhan W.Z., Mantilla C.B., Sieck G.C. Regulation of neuromuscular transmission by neurotrophins. Sheng Li Xue Bao 2003, 55(December (6)):617-624.
51. Knaepen K., Goekint M., Heyman E.M., Meeusen R. Neuroplasticity-exercise-induced response of peripheral brain-derived neurotrophic factor: A systematic review of experimental studies in human subjects. Sports Med 2010, 40(September (9)):765-801.
52. Ying Z., Roy R.R., Edgerton V.R., Gomez-Pinilla F. Voluntary exercise increases neurotrophin-3 and its receptor TrkC in the spinal cord. Brain Res 2003, 987(October (1)):93-99.