Hypercalcemia and pneumocystis Pneumonia after kidney transplantation: Report of an exceptional case and literature review

Transplant Infectious Disease

Volumn 13, Issue 5, 2011, Pages 496-500

  Chatzikyrkou, C ^a   Clajus, C ^a   Haubitz, M ^a   Hafer, C ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Calcitriol; Hypercalcemia; Pneumocystis jirovecii; Transplantation; Vitamin D

Indexed keywords

1,25 DIHYDROXYERGOCALCIFEROL; AMLODIPINE; CALCITRIOL; CALCIUM CARBONATE; COLECALCIFEROL; COTRIMOXAZOLE; DOXAZOSIN; EZETIMIBE; FUROSEMIDE; LEVOTHYROXINE; METOPROLOL; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PAMIDRONIC ACID; PANTOPRAZOLE; PREDNISOLONE; SIMVASTATIN; TACROLIMUS; VITAMIN D;

ADULT; ARTICLE; CALCIUM BLOOD LEVEL; CASE REPORT; CLINICAL FEATURE; DISEASE COURSE; DRUG DOSE INCREASE; DRUG WITHDRAWAL; FEMALE; HUMAN; HYPERCALCEMIA; KIDNEY TRANSPLANTATION; PARATHYROID HORMONE BLOOD LEVEL; PARATHYROIDECTOMY; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL; VITAMIN SUPPLEMENTATION;

HUMANS; HYPERCALCEMIA; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PNEUMOCYSTIS JIROVECII; PNEUMONIA, PNEUMOCYSTIS;

EID: 80053592215     PISSN: 13982273     EISSN: 13993062     Source Type: Journal    
DOI: 10.1111/j.1399-3062.2011.00623.x     Document Type: Article

References (18)

1. Thomas CF Jr, Limper AH. Pneumocystis pneumonia. N Engl J Med 2004; 350: 2487-2498.
2. Fishman JA. Infection in solid-organ transplant recipients. N Engl J Med 2007; 357: 2601-2614.
3. Martin SI, Fishman JA, AST Infectious Diseases Community of Practice. Pneumocystis pneumonia in solid organ transplant recipients. Am J Transplant 2009; 9 (Suppl 4): S227-S233.
4. Torres A, Lorenzo V, Salido E. Calcium metabolism and skeletal problems after transplantation. J Am Soc Nephrol 2002; 13: 551-558.
5. Chen WC, Chang SC, Wu TH, Yang WC, Tarng DC. Hypercalcemia in a renal transplant recipient suffering with Pneumocystis carinii pneumonia. Am J Kidney Dis 2002; 39: E8.
6. Hung YM. Pneumocystis carinii pneumonia with hypercalcemia and suppressed parathyroid hormone levels in a renal transplant patient. Transplantation 2006; 81: 639.
7. Aguirre AR, Balbo BE, Ianhez LE, da Costa MC, Andrade L. Hypercalcemia and suppressed PTH levels in a renal transplant patient infected with Pneumocystis carinii. Ren Fail 2007; 29: 513-516.
8. Hajji K, Dalle F, Harzallah A, Tanter Y, Rifle G, Mousson C. Vitamin D metabolite-mediated hypercalcemia with suppressed parathormone concentration in Pneumocystis jiroveci pneumonia after kidney transplantation. Transplant Proc 2009; 41: 3320-3322.
9. Jacobs MB. The acquired immunodeficiency syndrome and hypercalcemia. West J Med 1986; 144: 469-471.
10. Ahmed B, Jaspan JB. Case report: hypercalcemia in a patient with AIDS and Pneumocystis carinii pneumonia. Am J Med Sci 1993; 306: 313-316.
11. Mills AK, Wright SJ, Taylor KM, McCormack JG. Hypercalcaemia caused by Pneumocystis carinii pneumonia while in leukaemic remission. Aust N Z J Med 1999; 29: 102-103.
12. Bushinsky DA, Monk RD. Electrolyte quintet: calcium. Lancet 1998; 352: 306-311.
13. Lionakis MS, Samonis G, Kontoyiannis DP. Endocrine and metabolic manifestations of invasive fungal infections and systemic antifungal treatment. Mayo Clin Proc 2008; 83: 1046-1060.
14. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357: 266-281.
15. Stavroulopoulos A, Cassidy MJ, Porter CJ, Hosking DJ, Roe SD. Vitamin D status in renal transplant recipients. Am J Transplant 2007; 7: 2546-2552.
16. Doorenbos CR, van den Born J, Navis G, de Borst MH. Possible renoprotection by vitamin D in chronic renal disease: beyond mineral metabolism. Nat Rev Nephrol 2009; 5: 691-700.
17. Courbebaisse M, Thervet E, Souberbielle JC, et al. Effects of vitamin D supplementation on the calcium-phosphate balance in renal transplant patients. Kidney Int 2009; 75: 646-651.
18. Sharma OP. Vitamin D, calcium, and sarcoidosis. Chest 1996; 109: 535-539.