Fibrinogen alters mouse brain endothelial cell layer integrity affecting vascular endothelial cadherin

Biochemical and Biophysical Research Communications

Volumn 413, Issue 4, 2011, Pages 509-514

  Muradashvili, Nino ^a   Tyagi, Neetu ^a   Tyagi, Reeta ^a   Munjal, Charu ^a   Lominadze, David ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Fibrinogen; Intercellular adhesion molecule 1; Matrix metalloproteinases; Vascular endothelial cadherin

Indexed keywords

FIBRINOGEN; GELATINASE B; MESSENGER RNA; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL ADHESION; CELL CULTURE; CELL INTERACTION; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; MACROMOLECULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; TIGHT JUNCTION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANIMALS; BRAIN; CADHERINS; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; FIBRINOGEN; HUMANS; MATRIX METALLOPROTEINASE 9; MICE;

EID: 80053589731     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.07.133     Document Type: Article

References (36)

1. Danesh J., Lewington S., Thompson S.G., Lowe G.D., Collins R., Kostis J.B., Wilson A.C., Folsom A.R., Wu K., Benderly M., Goldbourt U., Willeit J., Kiechl S., Yarnell J.W., Sweetnam P.M., Elwood P.C., Cushman M., Psaty B.M., Tracy R.P., Tybjaerg-Hansen A., Haverkate F., de Maat M.P., Fowkes F.G., Lee A.J., Smith F.B., Salomaa V., Harald K., Rasi R., Vahtera E., Jousilahti P., Pekkanen J., D'Agostino R., Kannel W.B., Wilson P.W., Tofler G., Arocha-Pinango C.L., Rodriguez-Larralde A., Nagy E., Mijares M., Espinosa R., Rodriquez-Roa E., Ryder E., Diez-Ewald M.P., Campos G., Fernandez V., Torres E., Coll E., Marchioli R., Valagussa F., Rosengren A., Wilhelmsen L., Lappas G., Eriksson H., Cremer P., Nagel D., Curb J.D., Rodriguez B., Yano K., Salonen J.T., Nyyssonen K., Tuomainen T.P., Hedblad B., Lind P., Loewel H., Koenig W., Meade T.W., Cooper J.A., De Stavola B., Knottenbelt C., Miller G.J., Bauer K.A., Rosenberg R.D., Sato S., Kitamura A., Naito Y., Iso H., Rasi V., Palosuo T., Ducimetiere P., Amouyel P., Arveiler D., Evans A.E., Ferrieres J., Juhan-Vague I., Bingham A., Schulte H., Assmann G., Cantin B., Lamarche B., Despres J.P., Dagenais G.R., Tunstall-Pedoe H., Woodward M. Y. Ben Shlomo, S.G. Davey, V. Palmieri, J.L. Yeh, A. Rudnicka, P. Ridker, F. Rodeghiero, et al., Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA 2005, 294(14):1799-1809.
2. Lominadze D., Joshua I.G., Schuschke D.A. Increased erythrocyte aggregation in spontaneously hypertensive rats. Am. J. Hypertens. 1998, 11:784-789.
3. Letcher R.L., Chien S., Pickering T.G., Sealey J.E., Laragh J.H. Direct relationship between blood pressure and blood viscosity in normal and hypertensive subjects. Role of fibrinogen and concentration. Am. J. Med. 1981, 70:1195-1202.
4. Lee A.J., Lowe G.D.O., Woodward M., Tunstall-Pedoe H. Fibrinogen in relation to personal history of prevalent hypertension, diabetes, stroke, intermittent claudication, coronary heart disease, and family history: the Scottish Heart Health Study. Br. Heart J. 2007, 69:338-342.
5. Eidelman R.S., Hennekens C.H. Fibrinogen: a predictor of stroke and marker of atherosclerosis. Eur. Heart J. 2003, 24:499-500.
6. Lominadze D., Dean W.L., Tyagi S.C., Roberts A.M. Mechanisms of fibrinogen-induced microvascular dysfunction during cardiovascular disease. Acta Physiol. 2010, 198:1-13.
7. Lominadze D., Dean W.L. Involvement of fibrinogen specific binding in erythrocyte aggregation. Clin. Exp. Hypertens. 2002, 517:41-44.
8. Eber B., Schumacher M. Fibrinogen: its role in the hemostatic regulation in atherosclerosis. Semin. Thromb. Hemost. 1993, 19:104-107.
9. Bloom A.L. Physiology of blood coagulation. Haemostasis 1990, 20:14-29.
10. Languino L.R., Plescia J., Duperrray A., Brian A.A., Plow E.F., Geltosky J.E., Alteri D.C. Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway. Cell 1993, 73:1423-1434.
11. Tyagi N., Roberts A.M., Dean W.L., Tyagi S.C., Lominadze D. Fibrinogen induces endothelial cell permeability. Mol. Cell. Biochem. 2008, 307:13-22.
12. Patibandla P.K., Tyagi N., Dean W.L., Tyagi S.C., Roberts A.M., Lominadze D. Fibrinogen induces alterations of endothelial cell tight junction proteins. J. Cell. Physiol. 2009, 221:195-203.
13. Mehta D., Malik A.B. Signaling mechanisms regulating endothelial permeability. Physiol. Rev. 2006, 86:279-367.
14. Sen U., Tyagi N., Patibandla P.K., Dean W.L., Tyagi S.C., Roberts A.M., Lominadze D. Fibrinogen-induced endothelin-1 production from endothelial cells. AJP - Cell Physiol. 2009, 296:C840-C847.
15. Fernandez-Patron C., Zouki C., Whittal R., Chan J.S., Davidge S.T., Filep J.G. Matrix metalloproteinases regulate neutrophil-endothelial cell adhesion through generation of endothelin-1[1-32]. FASEB J. 2001, 15:2230-2240.
16. Rosell A., Ortega-Aznar A., Alvarez-Sabin J., Fernandez-Cadenas I., Ribo M., Molina C.A., Lo E.H., Montaner J. Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke. Stroke 2006, 37:1399-1406.
17. Chen F., Ohashi N., Li W., Eckman C., Nguyen J.H. Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure. Hepatology 2009, 50:1914-1923.
18. Vestweber D. VE-Cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscler. Thromb. Vasc. Biol. 2008, 28:223-232.
19. Bazzoni G., Dejana E. Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Physiol. Rev. 2004, 84:869-901.
20. Baldwin A., Thurston G. Mechanics of endothelial cell architecture and vascular permeability. Crit. Rev. Biomed. Eng. 2001, 29:247-278.
21. Lincoln D.W., Larsen A.M., Phillips P.G., Bove K. Isolation of murine aortic endothelial cells in culture and the effects of sex steroids on their growth. In Vitro Cell Dev. Biol. Anim. 2003, 39:140-145.
22. Mishra P., Metreveli N., Tyagi S. MMP-9 gene ablation and TIMP-4 mitigate PAR-1-mediated cardiomyocyte dysfunction: a plausible role of dicer and miRNA. Cell Biochem. Biophys. 2010, 57:67-76.
23. Lominadze D., Schuschke D.A., Joshua I.G., Dean W.L. Increased ability of erythrocytes to aggregate in spontaneously hypertensive rats. Clin. Exp. Hypertens. 2002, 24:397-406.
24. Kametani Y., Takeichi M. Basal-to-apical cadherin flow at cell junctions. Nat. Cell Biol. 2007, 9:92-98.
25. Patla I., Volberg T., Elad N., Hirschfeld-Warneken V., Grashoff C., Fassler R., Spatz J.P., Geiger B., Medalia O. Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography. Nat. Cell Biol. 2010, 12:909-915.
26. Lochhead J.J., McCaffrey G., Quigley C.E., Finch J., DeMarco K.M., Nametz N., Davis T.P. Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation. J. Cereb. Blood Flow Metab. 2010, 30:1625-1636.
27. Moshal K.S., Sen U., Tyagi N., Henderson B., Steed M., Ovechkin A.V., Tyagi S.C. Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway. Am. J. Physiol. - Cell Physiol. 2006, 290:C883-C891.
28. Touyz R.M. Mitochondrial redox control of matrix metalloproteinase signaling in resistance arteries. Arterioscler. Thromb. Vasc. Biol. 2006, 26:685-688.
29. Navaratna D., McGuire P.G., Menicucci G., Das A. Proteolytic degradation of VE-cadherin alters the blood-retinal barrier in diabetes. Diabetes 2007, 56:2380-2387.
30. Lominadze D., Roberts A.M., Tyagi N., Tyagi S.C. Homocysteine causes cerebrovascular leakage in mice. Am. J. Physiol. Heart Circ. Physiol. 2006, 290:H1206-H1213.
31. Bauer A.T., Burgers H.F., Rabie T., Marti H.H. Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement. J. Cereb. Blood Flow Metab. 2010, 30:837-848.
32. Nelson C.M., Pirone D.M., Tan J.L., Chen C.S. Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA. Mol. Biol. Cell 2004, 15:2943-2953.
33. Simpson-Haidaris P.J., Sahni A. Author's reply to Weijers et al. Fibrin β15-42 domain is cryptic in intact fibrinogen: comment on the study by A. Sahni et al. Int. J. Cancer 2010, 127:2982-2986.
34. Sahni A., Arévalo M.T., Sahni S.K., Simpson-Haidaris P.J. The VE-cadherin binding domain of fibrinogen induces endothelial barrier permeability and enhances transendothelial migration of malignant breast epithelial cells. Int. J. Cancer 2009, 125:577-584.
35. Boutcher P.A., Gaffney P.J., Raut S., O'Regan R.G., McLoughlin P. Effects of early plasmin digests of fibrinogen on isometric tension development in isolated rings of rat pulmonary artery. Thromb. Res. 1996, 81:231-239.
36. Gaffney P.J. Fibrin degradation products: a review of structures found in vitro and in vivo. Ann. NY Acad. Sci. 2001, 936:594-610.