Opportunities to minimise animal use in pharmaceutical regulatory general toxicology: A cross-company review

Regulatory Toxicology and Pharmacology

Volumn 61, Issue 2, 2011, Pages 222-229

  Sparrow, Susan S ^a   Robinson, Sally ^b   Bolam, Sue ^c   Bruce, Christopher ^d   Danks, Andy ^e   Everett, David ^f   Fulcher, Stephen ^g   Hill, Rose E ^h   Palmer, Helen ⁱ   Scott, Elspeth W ^j   Chapman, Kathryn L ^k  

^a GLAXOSMITHKLINE   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c Alnwick Research Centre   (United Kingdom)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^e CHARLES RIVER LABORATORIES   (United Kingdom)

^f Bioanalytical Department   (United Kingdom)

^g Harlan   (Switzerland)

^h SK10 4TJ   (United Kingdom)

ⁱ HUNTINGDON LIFE SCIENCES   (United Kingdom)

^j Midlothian Innovation Centre   (United Kingdom)

^k National Centre for the Replacement   (United Kingdom)

more..

Author keywords

Animal numbers; Group size; Pharmaceuticals; Regulatory toxicology; Study design; Toxicokinetics

Indexed keywords

ANIMAL USE; ARTICLE; CARCINOGENICITY; DRUG INDUSTRY; DRUG RESEARCH; EXPERIMENTAL ANIMAL; METHODOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RODENT; TOXICOKINETICS; TOXICOLOGY; UNITED KINGDOM;

ANIMAL EXPERIMENTATION; ANIMAL USE ALTERNATIVES; ANIMALS; DRUG INDUSTRY; HUMANS; RESEARCH DESIGN; RISK ASSESSMENT; TOXICITY TESTS;

ANIMALIA; RATTUS; RODENTIA;

EID: 80053588244     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2011.08.001     Document Type: Article

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