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Volumn 81, Issue 3, 2011, Pages

Prospective study of epidermal growth factor receptor tyrosine kinase inhibitors concurrent with individualized radiotherapy for patients with locally advanced or metastatic non-small-cell lung cancer

Author keywords

Concurrent treatment; Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs); Individualized radiotherapy; Non small cell lung cancer (NSCLC)

Indexed keywords

ACUTE TOXICITY; ADVERSE EVENTS; CONCURRENT TREATMENT; CURATIVE INTENT; EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS (EGFR-TKIS); EPIDERMAL GROWTH FACTOR RECEPTORS; EQUIVALENT DOSE; ERLOTINIB; ESOPHAGITIS; GEFITINIB; GROSS TUMOR VOLUME; LOCAL CONTROL; MEAN LUNG DOSE; MEDIAN SURVIVAL; NEUTROPENIA; NON SMALL CELL LUNG CANCER; NORMAL TISSUE; OVERALL SURVIVAL; OVERALL SURVIVAL RATES; PROGRESSION FREE SURVIVAL; PROSPECTIVE STUDY; PULMONARY TOXICITY; RADIATION DOSE; THROMBOCYTOPENIA; TUMOR PROGRESSIONS; TUMOR SIZE; VOLUME CONSTRAINT;

EID: 80053580476     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.12.035     Document Type: Article
Times cited : (65)

References (42)
  • 1
    • 24944549971 scopus 로고    scopus 로고
    • Radiation therapy for the treatment of unresected stage I-II non-small cell lung cancer
    • DOI 10.1378/chest.128.3.1461
    • J.P. Wisnivesky, M. Bonomi, and C. Henschke Radiation therapy for the treatment of unresected stage I-II non-small cell lung cancer Chest 128 2005 1461 1467 (Pubitemid 41324433)
    • (2005) Chest , vol.128 , Issue.3 , pp. 1461-1467
    • Wisnivesky, J.P.1    Bonomi, M.2    Henschke, C.3    Iannuzzi, M.4    McGinn, T.5
  • 2
    • 77949520655 scopus 로고    scopus 로고
    • Stereotactic body radiation therapy for inoperable early stage lung cancer
    • R. Timmerman, R. Paulus, and J. Galvin Stereotactic body radiation therapy for inoperable early stage lung cancer JAMA 303 2010 1070 1076
    • (2010) JAMA , vol.303 , pp. 1070-1076
    • Timmerman, R.1    Paulus, R.2    Galvin, J.3
  • 3
    • 74549188374 scopus 로고    scopus 로고
    • Toxicity report of a phase 1/2 dose-escalation study in patients with inoperable, locally advanced nonsmall cell lung cancer with helical tomotherapy and concurrent chemotherapy
    • S. Bral, M. Duchateau, and H. Versmessen Toxicity report of a phase 1/2 dose-escalation study in patients with inoperable, locally advanced nonsmall cell lung cancer with helical tomotherapy and concurrent chemotherapy Cancer 116 2010 241 250
    • (2010) Cancer , vol.116 , pp. 241-250
    • Bral, S.1    Duchateau, M.2    Versmessen, H.3
  • 4
    • 20544435485 scopus 로고    scopus 로고
    • Phase III study of the Eastern Cooperative Oncology Group (ECOG 2597): Induction chemotherapy followed by either standard thoracic radiotherapy or hyperfractionated accelerated radiotherapy for patients with unresectable stage IIIA and B non-small-cell lung cancer
    • C.P. Belani, W. Wang, and D.H. Johnson Phase III study of the Eastern Cooperative Oncology Group (ECOG 2597): Induction chemotherapy followed by either standard thoracic radiotherapy or hyperfractionated accelerated radiotherapy for patients with unresectable stage IIIA and B non-small-cell lung cancer J Clin Oncol 23 2005 3760 3767
    • (2005) J Clin Oncol , vol.23 , pp. 3760-3767
    • Belani, C.P.1    Wang, W.2    Johnson, D.H.3
  • 5
    • 17844390172 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: Current knowledge and future directions
    • W. Pao, and V.A. Miller Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: Current knowledge and future directions J Clin Oncol 23 2005 2556 2568
    • (2005) J Clin Oncol , vol.23 , pp. 2556-2568
    • Pao, W.1    Miller, V.A.2
  • 9
    • 77950538966 scopus 로고    scopus 로고
    • Phase II study of erlotinib in Japanese patients with advanced non-small cell lung cancer
    • T. Takahashi, N. Yamamoto, and T. Nukiwa Phase II study of erlotinib in Japanese patients with advanced non-small cell lung cancer Anticancer Res 30 2010 557 563
    • (2010) Anticancer Res , vol.30 , pp. 557-563
    • Takahashi, T.1    Yamamoto, N.2    Nukiwa, T.3
  • 12
    • 27544503230 scopus 로고    scopus 로고
    • Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
    • DOI 10.1016/S0140-6736(05)67625-8, PII S0140673605676258
    • N. Thatcher, A. Chang, and P. Parikh Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer) Lancet 366 2005 1527 1537 (Pubitemid 41540110)
    • (2005) Lancet , vol.366 , Issue.9496 , pp. 1527-1537
    • Thatcher, N.1    Chang, A.2    Parikh, P.3    Pereira, J.R.4    Ciuleanu, T.5    Von Pawel, J.6    Thongprasert, S.7    Tan, E.H.8    Pemberton, K.9    Archer, V.10    Carroll, K.11
  • 13
    • 56249109644 scopus 로고    scopus 로고
    • Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): A randomised phase III trial
    • E.S. Kim, V. Hirsh, and T. Mok Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): A randomised phase III trial Lancet 372 2008 1809 1818
    • (2008) Lancet , vol.372 , pp. 1809-1818
    • Kim, E.S.1    Hirsh, V.2    Mok, T.3
  • 14
    • 46049114551 scopus 로고    scopus 로고
    • Final survival and safety results from a multicenter, open-label, phase 3b trial of erlotinib in patients with advanced nonsmall cell lung cancer
    • DOI 10.1002/cncr.23490
    • D.R. Spigel, M. Lin, and V. O'Neill Final survival and safety results from a multicenter, open-label, phase 3b trial of erlotinib in patients with advanced nonsmall cell lung cancer Cancer 112 2008 2749 2755 (Pubitemid 351969220)
    • (2008) Cancer , vol.112 , Issue.12 , pp. 2749-2755
    • Spigel, D.R.1    Lin, M.2    O'Neill, V.3    Hainsworth, J.D.4
  • 16
    • 39749129748 scopus 로고    scopus 로고
    • Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity
    • DOI 10.1158/1078-0432.CCR-07-1606
    • T. Tanaka, A. Munshi, and C. Brooks Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity Clin Cancer Res 14 2008 1266 1273 (Pubitemid 351302576)
    • (2008) Clinical Cancer Research , vol.14 , Issue.4 , pp. 1266-1273
    • Tanaka, T.1    Munshi, A.2    Brooks, C.3    Liu, J.4    Hobbs, M.L.5    Meyn, R.E.6
  • 18
    • 80053595999 scopus 로고    scopus 로고
    • Pilot study of EGFR-TKIs in combination with radiation for patients with locally advanced and metastatic non-small lung cancer (Abstr.)
    • J. Wang, T. Xia, and Y. Wang Pilot study of EGFR-TKIs in combination with radiation for patients with locally advanced and metastatic non-small lung cancer (Abstr.) Int J Radiat Oncol Biol Phys 75 Suppl. 2009 2587a
    • (2009) Int J Radiat Oncol Biol Phys , vol.75 , Issue.SUPPL.
    • Wang, J.1    Xia, T.2    Wang, Y.3
  • 19
    • 33746841847 scopus 로고    scopus 로고
    • Promising clinical outcome of stereotactic body radiation therapy for patients with inoperable Stage I/II non-small-cell lung cancer
    • DOI 10.1016/j.ijrobp.2006.04.013, PII S0360301606006353
    • T. Xia, H. Li, and Q. Sun Promising clinical outcome of stereotactic body radiation therapy for patients with inoperable Stage I/II non-small-cell lung cancer Int J Radiat Oncol Biol Phys 66 2006 117 125 (Pubitemid 44175645)
    • (2006) International Journal of Radiation Oncology Biology Physics , vol.66 , Issue.1 , pp. 117-125
    • Xia, T.1    Li, H.2    Sun, Q.3    Wang, Y.4    Fan, N.5    Yu, Y.6    Li, P.7    Chang, J.Y.8
  • 22
    • 33751172931 scopus 로고    scopus 로고
    • Analysis of clinical and dosimetric factors associated with treatment-related pneumonitis (TRP) in patients with non-small-cell lung cancer (NSCLC) treated with concurrent chemotherapy and three-dimensional conformal radiotherapy (3D-CRT)
    • S. Wang, Z. Liao, and X. Wei Analysis of clinical and dosimetric factors associated with treatment-related pneumonitis (TRP) in patients with non-small-cell lung cancer (NSCLC) treated with concurrent chemotherapy and three-dimensional conformal radiotherapy (3D-CRT) Int J Radiat Oncol Biol Phys 66 2006 1399 1407
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 1399-1407
    • Wang, S.1    Liao, Z.2    Wei, X.3
  • 23
    • 57449090435 scopus 로고    scopus 로고
    • Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage III non-small-cell lung cancer: The Hoosier Oncology Group and U.S. Oncology
    • N. Hanna, M. Neubauer, and C. Yiannoutsos Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage III non-small-cell lung cancer: The Hoosier Oncology Group and U.S. Oncology J Clin Oncol 26 2008 5755 5760
    • (2008) J Clin Oncol , vol.26 , pp. 5755-5760
    • Hanna, N.1    Neubauer, M.2    Yiannoutsos, C.3
  • 26
    • 79251603976 scopus 로고    scopus 로고
    • Gefitinib in combination with irradiation with or without cisplatin in patients with inoperable stage III non-small cell lung cancer: A phase i trial
    • press
    • Rothschild S, Bucher SE, Bernier J, et al. Gefitinib in combination with irradiation with or without cisplatin in patients with inoperable stage III non-small cell lung cancer: A phase I trial. Int J Radiat Oncol Biol Phys. In press.
    • Int J Radiat Oncol Biol Phys.
    • Rothschild, S.1    Bucher, S.E.2    Bernier, J.3
  • 27
    • 58149132003 scopus 로고    scopus 로고
    • Phase i trial of erlotinib-based multimodality therapy for inoperable stage III non-small cell lung cancer
    • N.W. Choong, A.M. Mauer, and D.J. Haraf Phase I trial of erlotinib-based multimodality therapy for inoperable stage III non-small cell lung cancer J Thorac Oncol 3 2008 1003 1011
    • (2008) J Thorac Oncol , vol.3 , pp. 1003-1011
    • Choong, N.W.1    Mauer, A.M.2    Haraf, D.J.3
  • 28
    • 76149123903 scopus 로고    scopus 로고
    • A phase i study of gefitinib with concurrent dose-escalated weekly docetaxel and conformal three-dimensional thoracic radiation followed by consolidative docetaxel and maintenance gefitinib for patients with stage III non-small cell lung cancer
    • B. Center, W.J. Petty, and D. Ayala A phase I study of gefitinib with concurrent dose-escalated weekly docetaxel and conformal three-dimensional thoracic radiation followed by consolidative docetaxel and maintenance gefitinib for patients with stage III non-small cell lung cancer J Thorac Oncol 5 2010 69 74
    • (2010) J Thorac Oncol , vol.5 , pp. 69-74
    • Center, B.1    Petty, W.J.2    Ayala, D.3
  • 31
    • 41849138318 scopus 로고    scopus 로고
    • Involved-field radiotherapy is effective for patients 70 years old or more with early stage non-small cell lung cancer
    • H.M. Yu, Y.F. Liu, and J.M. Yu Involved-field radiotherapy is effective for patients 70 years old or more with early stage non-small cell lung cancer Radiother Oncol 87 2008 29 34
    • (2008) Radiother Oncol , vol.87 , pp. 29-34
    • Yu, H.M.1    Liu, Y.F.2    Yu, J.M.3
  • 33
    • 77956628128 scopus 로고    scopus 로고
    • Elective nodal irradiation (ENI) vs. involved field radiotherapy (IFRT) for locally advanced non-small cell lung cancer (NSCLC): A comparative analysis of toxicities and clinical outcomes
    • A.T. Fernandes, J. Shen, and J. Finlay Elective nodal irradiation (ENI) vs. involved field radiotherapy (IFRT) for locally advanced non-small cell lung cancer (NSCLC): A comparative analysis of toxicities and clinical outcomes Radiother Oncol 95 2010 178 184
    • (2010) Radiother Oncol , vol.95 , pp. 178-184
    • Fernandes, A.T.1    Shen, J.2    Finlay, J.3
  • 34
    • 78650373191 scopus 로고    scopus 로고
    • Outcomes of concurrent chemoradiotherapy in patients with stage III non-small-cell lung cancer and significant comorbidity
    • E.C. Phernambucq, F.O. Spoelstra, and W.F. Verbakel Outcomes of concurrent chemoradiotherapy in patients with stage III non-small-cell lung cancer and significant comorbidity Ann Oncol 22 2011 132 138
    • (2011) Ann Oncol , vol.22 , pp. 132-138
    • Phernambucq, E.C.1    Spoelstra, F.O.2    Verbakel, W.F.3
  • 35
    • 67651124771 scopus 로고    scopus 로고
    • A Phase II study of synchronous three-dimensional conformal boost to the gross tumor volume for patients with unresectable Stage III non-small-cell lung cancer: Results of Korean Radiation Oncology Group 0301 study
    • K.H. Cho, S.J. Ahn, and H.R. Pyo A Phase II study of synchronous three-dimensional conformal boost to the gross tumor volume for patients with unresectable Stage III non-small-cell lung cancer: Results of Korean Radiation Oncology Group 0301 study Int J Radiat Oncol Biol Phys 74 2009 1397 1404
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , pp. 1397-1404
    • Cho, K.H.1    Ahn, S.J.2    Pyo, H.R.3
  • 36
    • 77954722629 scopus 로고    scopus 로고
    • Phase III trial comparing docetaxel and cisplatin combination chemotherapy with mitomycin, vindesine, and cisplatin combination chemotherapy with concurrent thoracic radiotherapy in locally advanced non-small-cell lung cancer: OLCSG 0007
    • Y. Segawa, K. Kiura, and N. Takigawa Phase III trial comparing docetaxel and cisplatin combination chemotherapy with mitomycin, vindesine, and cisplatin combination chemotherapy with concurrent thoracic radiotherapy in locally advanced non-small-cell lung cancer: OLCSG 0007 J Clin Oncol 28 2010 3299 3306
    • (2010) J Clin Oncol , vol.28 , pp. 3299-3306
    • Segawa, Y.1    Kiura, K.2    Takigawa, N.3
  • 37
    • 77957287051 scopus 로고    scopus 로고
    • Phase III study comparing second- and third-generation regimens with concurrent thoracic radiotherapy in patients with unresectable stage III non-small-cell lung cancer: West Japan Thoracic Oncology Group WJTOG0105
    • N. Yamamoto, K. Nakagawa, and Y. Nishimura Phase III study comparing second- and third-generation regimens with concurrent thoracic radiotherapy in patients with unresectable stage III non-small-cell lung cancer: West Japan Thoracic Oncology Group WJTOG0105 J Clin Oncol 28 2010 3739 3745
    • (2010) J Clin Oncol , vol.28 , pp. 3739-3745
    • Yamamoto, N.1    Nakagawa, K.2    Nishimura, Y.3
  • 38
    • 77952298828 scopus 로고    scopus 로고
    • Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer
    • A. Auperin, C. Le Pechoux, and E. Rolland Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer J Clin Oncol 28 2010 2181 2190
    • (2010) J Clin Oncol , vol.28 , pp. 2181-2190
    • Auperin, A.1    Le Pechoux, C.2    Rolland, E.3
  • 39
    • 71549150592 scopus 로고    scopus 로고
    • Long-term survivors of more than 5 years in advanced non-small cell lung cancer
    • K. Kaira, T. Takahashi, and H. Murakami Long-term survivors of more than 5 years in advanced non-small cell lung cancer Lung Cancer 67 2010 120 123
    • (2010) Lung Cancer , vol.67 , pp. 120-123
    • Kaira, K.1    Takahashi, T.2    Murakami, H.3
  • 40
    • 33748745638 scopus 로고    scopus 로고
    • Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: A systematic review
    • PII 0124389420060500000018
    • R. Feld, S.S. Sridhar, and F.A. Shepherd Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: A systematic review J Thorac Oncol 1 2006 367 376 (Pubitemid 47163993)
    • (2006) Journal of Thoracic Oncology , vol.1 , Issue.4 , pp. 367-376
    • Feld, R.1    Sridhar, S.S.2    Shepherd, F.A.3    Mackay, J.A.4    Evans, W.K.5
  • 41
    • 77953541527 scopus 로고    scopus 로고
    • Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: A multicentre, randomised, placebo-controlled phase 3 study
    • F. Cappuzzo, T. Ciuleanu, and L. Stelmakh Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: A multicentre, randomised, placebo-controlled phase 3 study Lancet Oncol 11 2010 521 529
    • (2010) Lancet Oncol , vol.11 , pp. 521-529
    • Cappuzzo, F.1    Ciuleanu, T.2    Stelmakh, L.3
  • 42
    • 77649203360 scopus 로고    scopus 로고
    • Randomized phase III trial of platinum-doublet chemotherapy followed by gefitinib compared with continued platinum-doublet chemotherapy in Japanese patients with advanced non-small-cell lung cancer: Results of a west Japan thoracic oncology group trial (WJTOG0203)
    • K. Takeda, T. Hida, and T. Sato Randomized phase III trial of platinum-doublet chemotherapy followed by gefitinib compared with continued platinum-doublet chemotherapy in Japanese patients with advanced non-small-cell lung cancer: Results of a west Japan thoracic oncology group trial (WJTOG0203) J Clin Oncol 28 2010 753 760
    • (2010) J Clin Oncol , vol.28 , pp. 753-760
    • Takeda, K.1    Hida, T.2    Sato, T.3


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