메뉴 건너뛰기




Volumn 116, Issue 1, 2010, Pages 241-250

Toxicity report of a phase 1/2 dose-escalation study in patients with inoperable, locally advanced nonsmall cell lung cancer with helical Tomotherapy and Concurrent Chemotherapy

Author keywords

Chemoradiation; Dose escalation; Image guided radiotherapy; Intensity modulated radiotherapy; Lung cancer

Indexed keywords

CISPLATIN; DOCETAXEL; FLUORODEOXYGLUCOSE;

EID: 74549188374     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.24732     Document Type: Article
Times cited : (19)

References (45)
  • 1
    • 0018836391 scopus 로고
    • A prospective randomized study of various irradiation doses and fractionation schedules in the treatment of inoperable non-oat-cell carcinoma of the lung. Preliminary report by the Radiation Therapy Oncology Group
    • Perez CA, Stanley K, Rubin P, et al. A prospective randomized study of various irradiation doses and fractionation schedules in the treatment of inoperable non-oat-cell carcinoma of the lung. Preliminary report by the Radiation Therapy Oncology Group. Cancer. 1980;45:2744-2753.
    • (1980) Cancer , vol.45 , pp. 2744-2753
    • Perez, C.A.1    Stanley, K.2    Rubin, P.3
  • 2
    • 24944432301 scopus 로고    scopus 로고
    • High-dose radiation improved local tumor control and overall survival in patients with inoperable/ unresectable non-small-cell lung cancer: Long-term results of a radiation dose escalation study
    • Kong FM, Ten Haken RK, Schipper MJ, et al. High-dose radiation improved local tumor control and overall survival in patients with inoperable/ unresectable non-small-cell lung cancer: long-term results of a radiation dose escalation study. Int J Radiat Oncol Biol Phys. 2005;63:324-333.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 324-333
    • Kong, F.M.1    Ten Haken, R.K.2    Schipper, M.J.3
  • 3
    • 0030737527 scopus 로고    scopus 로고
    • Continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small-cell lung cancer: A randomised multicentre trial. CHART Steering Committee
    • Saunders M, Dische S, Barrett A, Harvey A, Gibson D, Parmar M. Continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small-cell lung cancer: a randomised multicentre trial. CHART Steering Committee. Lancet. 1997;350:161-165.
    • (1997) Lancet , vol.350 , pp. 161-165
    • Saunders, M.1    Dische, S.2    Barrett, A.3    Harvey, A.4    Gibson, D.5    Parmar, M.6
  • 4
    • 33746855492 scopus 로고    scopus 로고
    • Comparison of outcomes for patients with medically inoperable stage I non-small-cell lung cancer treated with 2-dimensional versus 3-dimensional radiotherapy
    • Fang LC, Komaki R, Allen P, Guerrero T, Mohan R, Cox JD. Comparison of outcomes for patients with medically inoperable stage I non-small-cell lung cancer treated with 2-dimensional versus 3-dimensional radiotherapy. Int J Radiat Oncol Biol Phys. 2006;66:108-116.
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 108-116
    • Fang, L.C.1    Komaki, R.2    Allen, P.3    Guerrero, T.4    Mohan, R.5    Cox, J.D.6
  • 5
    • 33644666024 scopus 로고    scopus 로고
    • Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): A meta-analysis of individual data from 1764 patients
    • Auperin A, Le Pechoux C, Pignon JP, et al. Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): a meta-analysis of individual data from 1764 patients. Ann Oncol. 2006;17:473-483.
    • (2006) Ann Oncol , vol.17 , pp. 473-483
    • Auperin, A.1    Le Pechoux, C.2    Pignon, J.P.3
  • 7
    • 25844472683 scopus 로고    scopus 로고
    • Effect of overall treatment time on outcomes after concurrent chemoradiation for locally advanced non-small-cell lung carcinoma: Analysis of the Radiation Therapy Oncology Group (RTOG) experience
    • Machtay M, Hsu C, Komaki R, et al. Effect of overall treatment time on outcomes after concurrent chemoradiation for locally advanced non-small-cell lung carcinoma: analysis of the Radiation Therapy Oncology Group (RTOG) experience. Int J Radiat Oncol Biol Phys. 2005; 63:667-671.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 667-671
    • Machtay, M.1    Hsu, C.2    Komaki, R.3
  • 8
    • 0033397766 scopus 로고    scopus 로고
    • Effect of docetaxel on the therapeutic ratio of fractionated radiotherapy in vivo
    • Mason KA, Kishi K, Hunter N, et al. Effect of docetaxel on the therapeutic ratio of fractionated radiotherapy in vivo. Clin Cancer Res. 1999;5:4191-4198.
    • (1999) Clin Cancer Res , vol.5 , pp. 4191-4198
    • Mason, K.A.1    Kishi, K.2    Hunter, N.3
  • 9
    • 0028843552 scopus 로고
    • Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small Cell Lung Cancer Collaborative Group
    • [No authors listed] Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small Cell Lung Cancer Collaborative Group. BMJ. 1995;311:899-909.
    • (1995) BMJ , vol.311 , pp. 899-909
  • 10
    • 19444365516 scopus 로고    scopus 로고
    • Platinum-based versus non-platinum-based chemotherapy in advanced non-small-cell lung cancer: A meta-analysis of the published literature
    • D'Addario G, Pintilie M, Leighl NB, Feld R, Cerny T, Shepherd FA. Platinum-based versus non-platinum-based chemotherapy in advanced non-small-cell lung cancer: a meta-analysis of the published literature. J Clin Oncol. 2005;23:2926-2936.
    • (2005) J Clin Oncol , vol.23 , pp. 2926-2936
    • D'Addario, G.1    Pintilie, M.2    Leighl, N.B.3    Feld, R.4    Cerny, T.5    Shepherd, F.A.6
  • 11
    • 4444313414 scopus 로고    scopus 로고
    • Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy
    • Kron T, Grigorov G, Yu E, et al. Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy. Phys Med Biol. 2004;49:3675-3690.
    • (2004) Phys Med Biol , vol.49 , pp. 3675-3690
    • Kron, T.1    Grigorov, G.2    Yu, E.3
  • 12
    • 57449090435 scopus 로고    scopus 로고
    • Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage III non-small-cell lung cancer: The Hoosier Oncology Group and U.S. Oncology
    • Hanna N, Neubauer M, Yiannoutsos C, et al. Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage III non-small-cell lung cancer: the Hoosier Oncology Group and U.S. Oncology. J Clin Oncol. 2008;26:5755-5760.
    • (2008) J Clin Oncol , vol.26 , pp. 5755-5760
    • Hanna, N.1    Neubauer, M.2    Yiannoutsos, C.3
  • 13
    • 21244442951 scopus 로고    scopus 로고
    • Selective mediastinal node irradiation based on FDG-PET scan data in patients with non-small-cell lung cancer: A prospective clinical study
    • De Ruysscher D, Wanders S, van Haren E, et al. Selective mediastinal node irradiation based on FDG-PET scan data in patients with non-small-cell lung cancer: a prospective clinical study. Int J Radiat Oncol Biol Phys. 2005;62:988-994.
    • (2005) Int J Radiat Oncol Biol Phys , vol.62 , pp. 988-994
    • De Ruysscher, D.1    Wanders, S.2    van Haren, E.3
  • 14
    • 0030926263 scopus 로고    scopus 로고
    • Regional lymph node classification for lung cancer staging
    • Mountain CF, Dresler CM. Regional lymph node classification for lung cancer staging. Chest. 1997;111:1718-1723.
    • (1997) Chest , vol.111 , pp. 1718-1723
    • Mountain, C.F.1    Dresler, C.M.2
  • 15
    • 0027141318 scopus 로고
    • Tomotherapy: A new concept for the delivery of dynamic conformal radiotherapy
    • Mackie TR, Holmes T, Swerdloff S, et al. Tomotherapy: a new concept for the delivery of dynamic conformal radiotherapy. Med Phys. 1993;20:1709-1719.
    • (1993) Med Phys , vol.20 , pp. 1709-1719
    • Mackie, T.R.1    Holmes, T.2    Swerdloff, S.3
  • 16
    • 33745495381 scopus 로고    scopus 로고
    • History of tomotherapy
    • Mackie TR. History of tomotherapy. Phys Med Biol. 2006;51:R427-R453.
    • (2006) Phys Med Biol , vol.51
    • Mackie, T.R.1
  • 17
    • 0037318974 scopus 로고    scopus 로고
    • Reduction in radiation dose to lung and other normal tissues using helical tomotherapy to treat lung cancer, in comparison to conventional field arrangements
    • Scrimger RA, Tome WA, Olivera GH, Reckwerdt PJ, Mehta MP, Fowler JF. Reduction in radiation dose to lung and other normal tissues using helical tomotherapy to treat lung cancer, in comparison to conventional field arrangements. Am J Clin Oncol. 2003;26:70-78.
    • (2003) Am J Clin Oncol , vol.26 , pp. 70-78
    • Scrimger, R.A.1    Tome, W.A.2    Olivera, G.H.3    Reckwerdt, P.J.4    Mehta, M.P.5    Fowler, J.F.6
  • 18
    • 2342583374 scopus 로고    scopus 로고
    • Is tomotherapy the future of IMRT?
    • Beavis AW. Is tomotherapy the future of IMRT? Br J Radiol. 2004;77:285-295.
    • (2004) Br J Radiol , vol.77 , pp. 285-295
    • Beavis, A.W.1
  • 19
    • 33750538454 scopus 로고    scopus 로고
    • Automatic registration of megavoltage to kilovoltage CT images in helical tomotherapy: An evaluation of the setup verification process for the special case of a rigid head phantom
    • Boswell S, Tome W, Jeraj R, Jaradat H, Mackie TR. Automatic registration of megavoltage to kilovoltage CT images in helical tomotherapy: an evaluation of the setup verification process for the special case of a rigid head phantom. Med Phys. 2006;33:4395-4404.
    • (2006) Med Phys , vol.33 , pp. 4395-4404
    • Boswell, S.1    Tome, W.2    Jeraj, R.3    Jaradat, H.4    Mackie, T.R.5
  • 20
    • 22144485867 scopus 로고    scopus 로고
    • Initial experience with megavoltage (MV) CT guidance for daily prostate alignments
    • Langen KM, Zhang Y, Andrews RD, et al. Initial experience with megavoltage (MV) CT guidance for daily prostate alignments. Int J Radiat Oncol Biol Phys. 2005; 62:1517-1524.
    • (2005) Int J Radiat Oncol Biol Phys , vol.62 , pp. 1517-1524
    • Langen, K.M.1    Zhang, Y.2    Andrews, R.D.3
  • 21
    • 34547131810 scopus 로고    scopus 로고
    • Optimization of megavoltage CT scan registration settings for thoracic cases on helical tomotherapy
    • Woodford C, Yartsev S, Van Dyk J. Optimization of megavoltage CT scan registration settings for thoracic cases on helical tomotherapy. Phys Med Biol. 2007;52:N345-N354.
    • (2007) Phys Med Biol , vol.52
    • Woodford, C.1    Yartsev, S.2    Van Dyk, J.3
  • 23
    • 0029281350 scopus 로고
    • LENT SOMA tables
    • [No authors listed] LENT SOMA tables. Radiother Oncol. 1995;35:17-60.
    • (1995) Radiother Oncol , vol.35 , pp. 17-60
  • 24
    • 52149101615 scopus 로고    scopus 로고
    • Complete metabolic tumour response, assessed by 18-fluorodeoxyglucose positron emission tomography (18FDG-PET), after induction chemotherapy predicts a favourable outcome in patients with locally advanced non-small cell lung cancer (NSCLC)
    • Decoster L, Schallier D, Everaert H, et al. Complete metabolic tumour response, assessed by 18-fluorodeoxyglucose positron emission tomography (18FDG-PET), after induction chemotherapy predicts a favourable outcome in patients with locally advanced non-small cell lung cancer (NSCLC). Lung Cancer. 2008;62:55-61.
    • (2008) Lung Cancer , vol.62 , pp. 55-61
    • Decoster, L.1    Schallier, D.2    Everaert, H.3
  • 25
    • 33746813139 scopus 로고    scopus 로고
    • Final results of a phase I/II dose escalation trial in non-small-cell lung cancer using 3-dimensional conformal radiotherapy
    • Belderbos JS, Heemsbergen WD, De JK, Baas P, Lebesque JV. Final results of a phase I/II dose escalation trial in non-small-cell lung cancer using 3-dimensional conformal radiotherapy. Int J Radiat Oncol Biol Phys. 2006;66:126-134.
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 126-134
    • Belderbos, J.S.1    Heemsbergen, W.D.2    De, J.K.3    Baas, P.4    Lebesque, J.V.5
  • 26
    • 33746760272 scopus 로고    scopus 로고
    • Final toxicity results of a radiation-dose escalation study in patients with non-small-cell lung cancer (NSCLC): Predictors for radiation pneumonitis and fibrosis
    • Kong FM, Hayman JA, Griffith KA, et al. Final toxicity results of a radiation-dose escalation study in patients with non-small-cell lung cancer (NSCLC): predictors for radiation pneumonitis and fibrosis. Int J Radiat Oncol Biol Phys. 2006;65:1075-1086.
    • (2006) Int J Radiat Oncol Biol Phys , vol.65 , pp. 1075-1086
    • Kong, F.M.1    Hayman, J.A.2    Griffith, K.A.3
  • 27
    • 12844271279 scopus 로고    scopus 로고
    • Toxicity and outcome results of RTOG 9311: A phase I-II dose-escalation study using 3-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma
    • Bradley J, Graham MV, Winter K, et al. Toxicity and outcome results of RTOG 9311: a phase I-II dose-escalation study using 3-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma. Int J Radiat Oncol Biol Phys. 2005;61:318-328.
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , pp. 318-328
    • Bradley, J.1    Graham, M.V.2    Winter, K.3
  • 28
    • 41849113379 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy (IMRT) for inoperable non-small cell lung cancer: The Memorial Sloan-Kettering Cancer Center (MSKCC) experience
    • Sura S, Gupta V, Yorke E, Jackson A, Amols H, Rosenzweig KE. Intensity-modulated radiation therapy (IMRT) for inoperable non-small cell lung cancer: the Memorial Sloan-Kettering Cancer Center (MSKCC) experience. Radiother Oncol. 2008;87:17-23.
    • (2008) Radiother Oncol , vol.87 , pp. 17-23
    • Sura, S.1    Gupta, V.2    Yorke, E.3    Jackson, A.4    Amols, H.5    Rosenzweig, K.E.6
  • 29
    • 12144290515 scopus 로고    scopus 로고
    • Dose and volume reduction for normal lung using intensity-modulated radiotherapy for advanced-stage non-small-cell lung cancer
    • Murshed H, Liu HH, Liao Z, et al. Dose and volume reduction for normal lung using intensity-modulated radiotherapy for advanced-stage non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2004;58:1258-1267.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 1258-1267
    • Murshed, H.1    Liu, H.H.2    Liao, Z.3
  • 30
    • 52049102221 scopus 로고    scopus 로고
    • Treatment planning comparison between conformal radiotherapy and helical tomotherapy in the case of locally advanced-stage NSCLC
    • Cattaneo GM, Dell'oca I, Broggi S, et al. Treatment planning comparison between conformal radiotherapy and helical tomotherapy in the case of locally advanced-stage NSCLC. Radiother Oncol. 2008;88:310-318.
    • (2008) Radiother Oncol , vol.88 , pp. 310-318
    • Cattaneo, G.M.1    Dell'oca, I.2    Broggi, S.3
  • 31
    • 12144286226 scopus 로고    scopus 로고
    • Feasibility of sparing lung and other thoracic structures with intensity-modulated radiotherapy for non-small-cell lung cancer
    • Liu HH, Wang X, Dong L, et al. Feasibility of sparing lung and other thoracic structures with intensity-modulated radiotherapy for non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2004;58:1268-1279.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 1268-1279
    • Liu, H.H.1    Wang, X.2    Dong, L.3
  • 32
    • 34247164024 scopus 로고    scopus 로고
    • Initial evaluation of treatment-related pneumonitis in advanced-stage non-small-cell lung cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy
    • Yom SS, Liao Z, Liu HH, et al. Initial evaluation of treatment-related pneumonitis in advanced-stage non-small-cell lung cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2007;68:94-102.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 94-102
    • Yom, S.S.1    Liao, Z.2    Liu, H.H.3
  • 33
    • 16544389343 scopus 로고    scopus 로고
    • Induction and concurrent chemotherapy with high-dose thoracic conformal radiation therapy in unresectable stage IIIA and IIIB non-small-cell lung cancer: A dose-escalation phase I trial
    • Socinski MA, Morris DE, Halle JS, et al. Induction and concurrent chemotherapy with high-dose thoracic conformal radiation therapy in unresectable stage IIIA and IIIB non-small-cell lung cancer: a dose-escalation phase I trial. J Clin Oncol. 2004;22:4341-4350.
    • (2004) J Clin Oncol , vol.22 , pp. 4341-4350
    • Socinski, M.A.1    Morris, D.E.2    Halle, J.S.3
  • 34
    • 40749114077 scopus 로고    scopus 로고
    • Concomitant radiochemotherapy (RT-CT) versus sequential RT-CT in locally advanced non-small cell lung cancer (NSCLC): A meta-analysis using individual patient data (IPD) from randomized clinical trials (RCTs)
    • Auperin A, Rolland E, Curran WJ, et al. Concomitant radiochemotherapy (RT-CT) versus sequential RT-CT in locally advanced non-small cell lung cancer (NSCLC): a meta-analysis using individual patient data (IPD) from randomized clinical trials (RCTs). J Thorac Oncol. 2007;2(4 suppl):s310.
    • (2007) J Thorac Oncol , vol.2 , Issue.4 SUPPL.
    • Auperin, A.1    Rolland, E.2    Curran, W.J.3
  • 35
    • 4444293137 scopus 로고    scopus 로고
    • Concurrent versus sequential chemoradiotherapy with cisplatin and vinorelbine in locally advanced non-small cell lung cancer: A randomized study
    • Zatloukal P, Petruzelka L, Zemanova M, et al. Concurrent versus sequential chemoradiotherapy with cisplatin and vinorelbine in locally advanced non-small cell lung cancer: a randomized study. Lung Cancer. 2004;46:87-98.
    • (2004) Lung Cancer , vol.46 , pp. 87-98
    • Zatloukal, P.1    Petruzelka, L.2    Zemanova, M.3
  • 36
    • 24944553737 scopus 로고    scopus 로고
    • Randomized phase III trial of sequential chemoradiotherapy compared with concurrent chemoradiotherapy in locally advanced non-small-cell lung cancer: Groupe Lyon-Saint-Etienne d'Oncologie Thoracique-Groupe Francais de Pneumo-Cancerologie NPC 95-01 Study
    • Fournel P, Robinet G, Thomas P, et al. Randomized phase III trial of sequential chemoradiotherapy compared with concurrent chemoradiotherapy in locally advanced non-small-cell lung cancer: Groupe Lyon-Saint-Etienne d'Oncologie Thoracique-Groupe Francais de Pneumo-Cancerologie NPC 95-01 Study. J Clin Oncol. 2005;23:5910-5917.
    • (2005) J Clin Oncol , vol.23 , pp. 5910-5917
    • Fournel, P.1    Robinet, G.2    Thomas, P.3
  • 37
    • 18044368457 scopus 로고    scopus 로고
    • Results of a phase I dose-escalation study using 3-dimensional conformal radiotherapy in the treatment of inoperable nonsmall cell lung carcinoma
    • Rosenzweig KE, Fox JL, Yorke E, et al. Results of a phase I dose-escalation study using 3-dimensional conformal radiotherapy in the treatment of inoperable nonsmall cell lung carcinoma. Cancer. 2005;103:2118-2127.
    • (2005) Cancer , vol.103 , pp. 2118-2127
    • Rosenzweig, K.E.1    Fox, J.L.2    Yorke, E.3
  • 38
    • 0032840324 scopus 로고    scopus 로고
    • Clinical dose-volume histogram analysis for pneumonitis after 3D treatment for non-small cell lung cancer (NSCLC)
    • Graham MV, Purdy JA, Emami B, et al. Clinical dose-volume histogram analysis for pneumonitis after 3D treatment for non-small cell lung cancer (NSCLC). Int J Radiat Oncol Biol Phys. 1999;45:323-329.
    • (1999) Int J Radiat Oncol Biol Phys , vol.45 , pp. 323-329
    • Graham, M.V.1    Purdy, J.A.2    Emami, B.3
  • 39
    • 0031688620 scopus 로고    scopus 로고
    • Radiation pneumonitis as a function of mean lung dose: An analysis of pooled data of 540 patients
    • Kwa SL, Lebesque JV, Theuws JC, et al. Radiation pneumonitis as a function of mean lung dose: an analysis of pooled data of 540 patients. Int J Radiat Oncol Biol Phys. 1998;42:1-9.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 1-9
    • Kwa, S.L.1    Lebesque, J.V.2    Theuws, J.C.3
  • 40
    • 57749169285 scopus 로고    scopus 로고
    • Dose escalated, hypofractionated radiotherapy using helical tomotherapy for inoperable non-small cell lung cancer: Preliminary results of a risk-stratified phase I dose escalation study
    • Adkison JB, Khuntia D, Bentzen SM, et al. Dose escalated, hypofractionated radiotherapy using helical tomotherapy for inoperable non-small cell lung cancer: preliminary results of a risk-stratified phase I dose escalation study. Technol Cancer Res Treat. 2008;7:441-447.
    • (2008) Technol Cancer Res Treat , vol.7 , pp. 441-447
    • Adkison, J.B.1    Khuntia, D.2    Bentzen, S.M.3
  • 41
    • 44449123472 scopus 로고    scopus 로고
    • Irradiation of varying volumes of rat lung to same mean lung dose: A little to a lot or a lot to a little?
    • Semenenko VA, Molthen RC, et al. Irradiation of varying volumes of rat lung to same mean lung dose: a little to a lot or a lot to a little? Int J Radiat Oncol Biol Phys. 2008;71:838-847.
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , pp. 838-847
    • Semenenko, V.A.1    Molthen, R.C.2
  • 42
    • 0043092406 scopus 로고    scopus 로고
    • A little to a lot or a lot to a little? An analysis of pneumonitis risk from dose-volume histogram parameters of the lung in patients with lung cancer treated with 3-D conformal radiotherapy
    • Willner J, Jost A, Baier K, Flentje M. A little to a lot or a lot to a little? An analysis of pneumonitis risk from dose-volume histogram parameters of the lung in patients with lung cancer treated with 3-D conformal radiotherapy. Strahlenther Onkol. 2003;179:548-556.
    • (2003) Strahlenther Onkol , vol.179 , pp. 548-556
    • Willner, J.1    Jost, A.2    Baier, K.3    Flentje, M.4
  • 43
    • 0345269968 scopus 로고    scopus 로고
    • The relationship between local dose and loss of function for irradiated lung
    • Gopal R, Tucker SL, Komaki R, et al. The relationship between local dose and loss of function for irradiated lung. Int J Radiat Oncol Biol Phys. 2003;56:106-113.
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 106-113
    • Gopal, R.1    Tucker, S.L.2    Komaki, R.3
  • 44
    • 45149128875 scopus 로고    scopus 로고
    • Randomized phase II trial of induction chemotherapy followed by concurrent chemotherapy and dose-escalated thoracic conformal radiotherapy (74 Gy) in stage III non-small-cell lung cancer: CALGB 30105
    • Socinski MA, Blackstock AW, Bogart JA, et al. Randomized phase II trial of induction chemotherapy followed by concurrent chemotherapy and dose-escalated thoracic conformal radiotherapy (74 Gy) in stage III non-small-cell lung cancer: CALGB 30105. J Clin Oncol. 2008;26:2457-2463.
    • (2008) J Clin Oncol , vol.26 , pp. 2457-2463
    • Socinski, M.A.1    Blackstock, A.W.2    Bogart, J.A.3
  • 45
    • 0029591692 scopus 로고
    • Incorporating toxicity considerations into the design of two-stages phase II clinical trials
    • Bryant J, Day R. Incorporating toxicity considerations into the design of two-stages phase II clinical trials. Biometrics. 1995;51:1372-1383.
    • (1995) Biometrics , vol.51 , pp. 1372-1383
    • Bryant, J.1    Day, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.