Determination of HCV genotypes and viral loads in chronic HCV infected patients of Hazara Pakistan

Virology Journal

Volumn 8, Issue , 2011, Pages

  Ali, Amjad ^a   Nisar, Muhammad ^a   Ahmad, Habib ^b   Saif, Nausheen ^a   Idrees, Muhammad ^c   Bajwa, Mohammad A ^d  

^a UNIVERSITY OF MALAKAND   (Pakistan)

^b HAZARA UNIVERSITY   (Pakistan)

^c UNIVERSITY OF THE PUNJAB   (Pakistan)

^d University of Punjab Lahore ^*  (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; FEMALE; GENETIC VARIABILITY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PAKISTAN; VIRUS LOAD; ADOLESCENT; ADULT; AGED; BLOOD; CHILD; CLASSIFICATION; GENETICS; GENOTYPE; HOSPITALIZATION; MIDDLE AGED; MIXED INFECTION; MOLECULAR TYPING; PHYLOGEOGRAPHY; PREVALENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY;

HEPATITIS C VIRUS;

VIRUS RNA;

ADOLESCENT; ADULT; AGED; CHILD; COINFECTION; FEMALE; GENOTYPE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; MALE; MIDDLE AGED; MOLECULAR TYPING; PAKISTAN; PHYLOGEOGRAPHY; PREVALENCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SEVERITY OF ILLNESS INDEX; VIRAL LOAD;

EID: 80053577419     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-8-466     Document Type: Article

References (43)

1. Genetic diversity and evolution of hepatitis C virus - 15 years on. Simmonds P, J Gen Virol 2004 85 3173 3188 10.1099/vir.0.80401-0 15483230 (Pubitemid 39445434)
2. Natural history of HCV infection. Poynard T, Ratziu V, Benhamou Y, Opolon P, Cacoub P, Bedossa P, Best Pract Res Clin Gastroenterol 2000 14 211 228 10.1053/bega.1999.0071 (Pubitemid 30398316)
3. The changing epidemiology pattern and frequency distribution of hepatitis C virus in Pakistan. Butt S, Idrees M, Akbar H, Rehman I, Awan Z, Afzal S, Infect Genet Evol 2010 10 595 600 10.1016/j.meegid.2010.04.012 20438863
4. Molecular Epidemiology of HCV among Health Care Workers of Khyber Pakhtunkhwa. Khan S, Attaullah S, Ayaz S, N Khan S, Shams S, Ali I, Bilal M, Siraj S, Virology Journal 2011 8 105 10.1186/1743-422X-8-105 21385397
5. Frequency distribution of hepatitis C virus genotypes in different geographical regions of Pakistan and their possible routes of transmission. Idrees M, Riazuddin S, BMC Infect Dis 2008 8 69
6. High prevalence of hepatitis C virus infection in the largest province of Pakistan. Idrees M, Lal A, Naseem M, Khalid M, J Dig Dis 2008 9 95 103 10.1111/j.1751-2980.2008.00329.x 18419643 (Pubitemid 351566631)
7. Genetic organization and diversity of the hepatitis C virus. Choo QL, Richman KH, Han JH, Berger K, Lee C, Dong C, Gallegos C, Coit D, Medina-Selby R, Barr PJ, Weiner A, Bradley DW, Kuo G, Houghton M, Proc Natl Acad Sci USA 1991 88 2451 2455 10.1073/pnas.88.6.2451 1848704 (Pubitemid 21916435)
8. Genomic structure of the human prototype strain H of hepatitis C virus: comparison with American and Japanese isolates. Inchauspe G, Zebedee S, Lee DH, Sugitani M, Nasoff M, Prince AM, Proc Natl Acad Sci USA 1991 88 10292 20296 10.1073/pnas.88.22.10292 1658800
9. Hepatitis C virus. Lemon SM, Walker CM, Alter MJ, Yi M, Fields Virology Lippincot Williams and Wilkins, Philadelpia 2007 1253 1304
10. Hepatitis C genotypes: current trends and future implications. Zein NN, Persing D, Mayo Clin Proc 1996 71 458 462 10.4065/71.5.458 8628025 (Pubitemid 26144150)
11. Distribution of HCV genotypes and HCV RNA viral load in different geographical regions of Mexico. Jimenez-M R, Urbie-S F, Guillen L-P, Garza C-L, Hernandez Ca-G, Annals Hepatology 2010 9 33 39
12. Chronic hepatitis and genotyping: the clinical significance of determining HCV genotypes. Hanatyszyn HJ, Antiviral Ther 2005 10 1 11
13. Frequent recovery and broad genotype 2 diversity characterize hepatitis C virus infection in Ghana, West Africa. Candotti D, Temple J, Sarkodie F, Allain JP, J Virol 2003 77 7914 7923 10.1128/JVI.77.14.7914-7923.2003 12829831 (Pubitemid 36792788)
14. Phylogenetic analysis of hepatitis C virus isolates indicates a unique pattern of endemic infection in Cameroon. Ndjomou J, Pybus OG, Matz B, J Gen Virol 2003 84 2333 2341 10.1099/vir.0.19240-0 12917453 (Pubitemid 37063121)
15. A novel hepatitis C virus (HCV) subtype from Somalia and its classification into HCV clade 3. Abid K, Quadri R, Veuthey AL, Hadengue A, Negro F, J Gen Virol 2000 81 1485 1493 10811932 (Pubitemid 30342896)
16. Relationship between hepatitis C virus genotypes and sources of infection in patients with chronic hepatitis C. Pawlotsky JM, Tsakiris L, Roudot-Thoraval F, Pellet C, Stuyver L, Duval J, Dhumeaux D, J Infect Dis 1995 171 1607 1610 10.1093/infdis/171.6.1607 7769300
17. Complete nucleotide sequence of a type 4 hepatitis C virus variant, the predominant genotype in the Middle East. Chamberlain RW, Adams N, Saeed AA, Simmonds P, Elliott RM, J Gen Virol 1997 78 Pt 6 1341 1347 9191927 (Pubitemid 27281332)
18. Genotype and viral load as prognostic indicators in the treatment of hepatitis C. Trepo C, Journal of Viral Hepatitis 2000 7250 257
19. Detection of hepatitis C virus by polymerase chain reaction and response to interferon-a therapy: relationship to genotypes of hepatitis C virus. Yoshioka K, Kakumu S, Wakita T, Hepatology 1992 16 293 299 10.1002/hep. 1840160203 1322348
20. Pretreatment serum hepatitic C virus RNA levels and hepatitis C virus genotype are the main and independent prognostic factors of sustained response to interferon alfa therapy in chronic hepatitis C. Martinot-Peignoux M, Marcellin P, Pouteau M, Hepatology 1995 22 1050 1056 7557850
21. Genotype, viral load and age as independent predictors of treatment outcome of interferon- 2a treatment in patients with chronic hepatitis C. Bell H, Hellum K, Harthug S, Scand J Infect Dis 1997 29 17 22 10.3109/ 00365549709008658 9112292
22. HCV genotypes and Quasipcies. Hepatitis C support project. Franciscus A, 2006 http://www.hcvadvocate.org
23. Peginterferon-alpha-2a (40KD) and ribavirin for 16 or 24 weeks in patients with genotype 2 or 3 chronic hepatitis C. Von Wagner M, Huber M, Berg T, Gastroenterology 2005 129 522 7 16083709 (Pubitemid 41096640)
24. Treatment with pegylated interferon and ribavarin in HCV infection with genotype 2 or 3 for 14 weeks: a pilot study. Dalgard O, Bjoro K, Hellum KB, Hepatology 2004 40 1260 5 10.1002/hep.20467 15558712 (Pubitemid 39656999)
25. Comparison of HCV RNA levels by branched DNA probe assay and by competitive polymerase chain reaction to predict effectiveness of interferon treatment for patients with chronic hepatitis C virus. Hayashi J, Kawakami Y, Nabeshima A, Dig Dis Sci 1998 43 384 391 10.1023/A:1018874910195 9512135 (Pubitemid 28124618)
26. Earlier loss of hepatitis C virus RNA in interferon therapy can predict a long-term response in chronic hepatitis C. Kakumu S, Aiyama T, Okumura A, Iwata K, Ishikawa T, Yoshioka K, J Gastroenterol Hepatol 1997 12 468 472 10.1111/j.1440-1746.1997.tb00468.x 9195406 (Pubitemid 27244490)
27. The treatment of hepatitis C: history, presence and future. Vrolijk JM, de Knegt RJ, Veldt BJ, Orlent H, Schalm SW, Neth J Med 2004 62 76 82 15209471 (Pubitemid 39089464)
28. HCV genotype distribution and possible transmission risks in Lahore, Pakistan. Ahmad W, Ijaz B, Javed TF, Jahan S, Shahid I, Khan FM, Hassan S, World J Gastroenterol 2010 16 4321 4328 10.3748/wjg.v16.i34.4321 20818816
29. Molecular epidemiology of Hepatitis C virus genotypes in Khyber Pakhtoonkhaw of Pakistan. Ali A, Ahmed H, Idrees M, Virol J 2010 203 1 7
30. Hepatitis C virus genotype circulating in district Swat of Khyber Pakhtoonkhaw, Pakistan. Inamullah Idrees M, Ahmed H, Ghafoor S, Ali M, Ali L, Ahmed A, Virology Journal 2011 8 16
31. Common genotypes of hepatitis C virus present in Pakistan. Idrees M, Pak J Med Res 2001 40 46 49
32. Development of an improved HCV Genotyping Assay for the Detection of Common Genotypes and subtypes in Pakistan. Idrees M, J Virol Meth 2008 150 50 56 10.1016/j.jviromet.2008.03.001
33. Mansehra-an introduction, science-religion Dialogue. Ghulam M, 2003 20 50 61
34. Epidemiological manifestations of hepatitis C virus genotypes and its association with potential risk factors among Libyan patients. Elasifer AH, Agnnyia YM, Al-Alagi BA, Daw MA, Virology Journal 2010 7 317 10.1186/1743-422X-7-317 21073743
35. Frequency of hepatitis "C" in Buner, NWFP. Muhammad N, Jan MA, J Coll Physicians Surg Pak 2005 15 11 14 15670516
36. Hepatitis C virus genotype 3a with phylogenetically distinct origin is circulating in Pakistan. Rehman I, Idrees M, Ali M, Ali L, Butt S, Hussain A, Akbar H, Afzal S, Genetic Vaccines and Therapy 2011 9 2 10.1186/1479-0556-9-2 21211024
37. Prevalence of hepatitis C virus (HCV) genotypes in Balochistan. Sarwat A, Naeem M, Hussain A, Kakar N, Babar ME, Ahmad J, Mol Biol Rep 2008
38. Distribution of hepatitis C virus genotypes in patients with chronic hepatitis C infection in Western Turkey. Altuglu I, Soyler I, Ozacar T, Erensoy S, Int J Infect Dis 2008 12 239 244 10.1016/j.ijid.2007.07.003 17942359 (Pubitemid 351539094)
39. Hepatitis C virus infection in the general population: a community-based study in West Bengal, India. Chowdhury A, Santra A, Chaudhuri S, Dhali GK, Chaudhuri S, Maity SG, Naik TN, Bhattacharya SK, Mazumder DN, Hepatology 2003 37 802 809 10.1053/jhep.2003.50157 12668973 (Pubitemid 36397391)
40. Analysis of HCV genotypes from blood donors shows three new HCV types 6 subgroups exist in Myanmar. Shinji T, Kyaw Y, Gokan K, Tanaka Y, Ochi K, Acta Med Okayama 2004 58 3 135 42 15471435 (Pubitemid 38981233)
41. Hepatitis C virus variants from Thailand classifiable into five novel genotypes in the sixth (6b), seventh (7c, 7d) and ninth (9b, 9c) major genetic groups. Tokita H, Okamoto H, Luengrojanakul P, Vareesangthip K, Chainuvati T, Iizuka H, Tsuda F, Miyakawa Y, Mayumi M, J Gen Virol 1995 76 2329 2335 10.1099/0022-1317-76-9-2329 7561773
42. Quantifcation of the initial decline of serum hepatitis C virus RNA and response to interferon alfa. Zeuzem S, Lee JH, Franke A, Hepatology 1998 27 1149 1156 10.1002/hep.510270433 9537457 (Pubitemid 28160503)
43. Mechanism of antiviral treatment efficacy and failure in chronic hepatitis C. Pawlotsky JM, Antiviral Res 2003 59 1 11 10.1016/S0166-3542(03) 00088-3 12834855 (Pubitemid 36773885)