Economic impact of use of chlorhexidine-impregnated sponge dressing for prevention of central line-associated infections in the United States

American Journal of Infection Control

Volumn 39, Issue 8, 2011, Pages 647-654

  Ye, Xin ^a   Rupnow, Marcia ^a   Bastide, Philippe ^a   Lafuma, Antoine ^b   Ovington, Liza ^a   Jarvis, William R ^c  

^a ETHICON INC   (United States)

^b CEMKA EVAL   (France)

^c Cemka Eval Outcomes Research and Epidemiology ^*

Author keywords

central line associated infections; Chlorhexidine impregnated sponge dressing; cost; economic

Indexed keywords

CHLORHEXIDINE; POLYURETHAN;

ANTISEPSIS; ARTICLE; BLOODSTREAM INFECTION; CATHETER INFECTION; CENTRAL VENOUS CATHETER; DECISION TREE; ECONOMIC EVALUATION; HEALTH ECONOMICS; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INFECTION RISK; LENGTH OF STAY; MAJOR CLINICAL STUDY; MATERIALS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REIMBURSEMENT; RISK REDUCTION; SKIN; UNITED STATES; WOUND DRESSING;

ANTI-INFECTIVE AGENTS, LOCAL; BACTEREMIA; BANDAGES; CATHETER-RELATED INFECTIONS; CATHETERIZATION, CENTRAL VENOUS; CATHETERS, INDWELLING; CHLORHEXIDINE; COST-BENEFIT ANALYSIS; EQUIPMENT CONTAMINATION; HUMANS; OUTCOME ASSESSMENT (HEALTH CARE); UNITED STATES;

EID: 80053572982     PISSN: 01966553     EISSN: 15273296     Source Type: Journal    
DOI: 10.1016/j.ajic.2010.11.008     Document Type: Article

References (29)

1. D.G. Maki, D.M. Kluger, and C.J. Crnich The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies Mayo Clin Proc 81 2006 1159 1171 (Pubitemid 44316281)
2. L.A. Mermel Prevention of intravascular catheter-related infections Ann Intern Med 132 2000 391 402 (Pubitemid 30127778)
3. National Nosocomial Infections Surveillance System National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1992 through June 2004, issued October 2004 Am J Infect Control 32 2004 470 485
4. D. Pittet, D. Tarara, and R. Wenzel Nosocomial bloodstream infection in critically ill patients. Excess length of stay, extra costs, and attributable mortality JAMA 271 1994 1819 1820
5. L. Soufir, J.F. Timsit, C. Mahe, J. Carlet, B. Regnier, and S. Chevret Attributable morbidity and mortality of catheter-related septicemia in critically ill patients: a matched, risk-adjusted, cohort study Infect Control Hosp Epidemiol 20 1999 396 401
6. B. Renaud, and C. Brun-Buisson ICU-Bacteremia Study Group. Outcomes of primary and catheter-related bacteremia: a cohort and case-control study in critically ill patients Am J Respir Crit Care Med 163 2001 1584 1590 (Pubitemid 32578760)
7. B.J. Rijnders, E. Van Wijngaerden, and W.E. Peetermans Catheter-tip colonization as a surrogate end point in clinical studies on catheter-related bloodstream infection: how strong is the evidence? Clin Infect Dis 35 2002 1053 1058 (Pubitemid 35239464)
8. J.F. Timsit, C. Schwebel, L. Bouadma, A. Geffroy, M. Garrouste-Orgeas, and S. Pease Dressing Study Group. Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial JAMA 301 2009 1231 1241
9. H. Ruschulte, M. Franke, P. Gastmeier, S. Zenz, K.H. Mahr, and S. Buchholz Prevention of central venous catheter related infections with chlorhexidine gluconate impregnated wound dressings: a randomized controlled trial Ann Hematol 88 2009 267 272
10. S.C. Wu, R.T. Crews, C. Zelen, J.S. Wrobel, and D.G. Armstrong Use of chlorhexidine-impregnated patch at pin site to reduce local morbidity: the ChIPPS Pilot Trial Int Wound J 5 2008 416 422 (Pubitemid 351874514)
11. I. Levy, J. Katz, E. Solter, Z. Samra, B. Vidne, and E. Birk Chlorhexidine-impregnated dressing for prevention of colonization of central venous catheters in infants and children: a randomized controlled study Pediatr Infect Dis J 24 2005 676 679 (Pubitemid 41140948)
12. J.S. Garland, C.P. Alex, C.D. Mueller, D. Otten, C. Shivpuri, and M.C. Harris A randomized trial comparing povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates Pediatrics 107 2001 1431 1436
13. BIOPATCH prescribing information. Somerville, NJ: Johnson & Johnson Wound Management, a Division of ETHICON, INC. Available from: www.biopatch.com. Accessed February 6, 2010.
14. Centers for Medicare and Medicaid Services (CMS). Quality measures compendium. Volume 2.0 December 2007. Medicaid and SCHIP quality improvement. Available from: http://www.cms.hhs.gov/MedicaidCHIPQualPrac/Downloads/ pmfinalaugust06.pdf. Accessed February 15, 2010.
15. C.A. Brauer, P.J. Neumann, and A.B. Rosen Trends in cost effectiveness analyses in orthopaedic surgery Clin Orthop Relat Res 457 2007 42 48 (Pubitemid 46573395)
16. A.G. Crawford, J.P. Fuhr Jr., and B. Rao Cost-benefit analysis of chlorhexidine gluconate dressing in the prevention of catheter-related bloodstream infections Infect Control Hosp Epidemiol 25 2004 668 674 (Pubitemid 39095050)
17. J.R. Edwards, K.D. Peterson, Y. Mu, S. Banerjee, K. Allen-Bridson, and G. Morrell National Healthcare Safety Network (NHSN) report, data summary for 2006 through 2008, issued November 2009 Am J Infect Control 37 2009 783 805
18. C.J. Crnich, and D.G. Maki The promise of novel technology for the prevention of intravascular device-related bloodstream infection. I. Pathogenesis and short-term devices Clin Infect Dis 34 2002 1232 1242 (Pubitemid 34450672)
19. L.B. Pemberton, V. Ross, P. Cuddy, H. Kremer, T. Fessler, and E. McGurk No difference in catheter sepsis between standard and antiseptic central venous catheters: a prospective randomized trial Arch Surg 131 1996 986 989 (Pubitemid 26300101)
20. S. Vokurka, K. Kabatova-Maxova, J. Skardova, and E. Bystricka Antimicrobial chlorhexidine/silver sulfadiazine-coated central venous catheters versus those uncoated in patients undergoing allogeneic stem cell transplantation Support Care Cancer 17 2009 145 151
21. K.M. Ho, and E. Litton Use of chlorhexidine-impregnated dressing to prevent vascular and epidural catheter colonization and infection: a meta-analysis J Antimicrob Chemother 58 2006 281 287 (Pubitemid 44294936)
22. N.P. O'Grady, M. Alexander, E.P. Dellinger, J.L. Gerberding, S.O. Heard, and D.G. Maki Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention MMWR Recomm Rep 51 2002 1 29
23. S. Saint, D.L. Veenstra, and B.A. Lipsky The clinical and economic consequences of nosocomial central venous catheter-related infection: are antimicrobial catheters useful? Infect Control Hosp Epidemiol 21 2000 375 380
24. A.M. Elward, C.S. Hollenbeak, D.K. Warren, and V.J. Fraser Attributable cost of nosocomial primary bloodstream infection in pediatric intensive care unit patients Pediatrics 115 2005 868 872
25. B.D. Cookson, M.C. Bolton, and J.H. Platt Chlorhexidine resistance in methicillin-resistant Staphylococcus aureus or just an elevated MIC? An in vitro and in vivo assessment Antimicrob Agents Chemother 35 1991 1997 2002
26. J.T. Wang, W.H. Sheng, J.L. Wang, D. Chen, M.L. Chen, and Y.C. Chen Longitudinal analysis of chlorhexidine susceptibilities of nosocomial methicillin-resistant Staphylococcus aureus isolates at a teaching hospital in Taiwan J Antimicrob Chemother 62 2008 514 517
27. J.D. Edgeworth Has decolonization played a central role in the decline in UK methicillin-resistant Staphylococcus aureus transmission? A focus on evidence from intensive care J Antimicrob Chemother 66 Suppl 2 2011 ii41-7
28. N. Safdar, and D.G. Maki The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters Intensive Care Med 30 2004 62 67 (Pubitemid 38147108)
29. Johnson & Johnson Wound Management, a Division of Ethicon, Inc. Price list, February 2009. Available from: http://www.ethicon360.com/products/ biopatch-protective-disk-chg. Accessed June 1, 2011.