Comparing 3 methods of monitoring gentamicin concentrations in patients with febrile neutropenia

Therapeutic Drug Monitoring

Volumn 33, Issue 5, 2011, Pages 592-601

  Avent, Minyon L ^a,b,c   Teoh, Junlu ^a   Lees, Judith ^d   Eckert, Kerena A ^e   Kirkpatrick, Carl M ^f,g  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c Medication Services Queensland   (Australia)

^d ROYAL ADELAIDE HOSPITAL   (Australia)

^e UNIVERSITY OF ADELAIDE   (Australia)

^f UNIVERSITY OF QUEENSLAND   (Australia)

^g MONASH UNIVERSITY   (Australia)

Author keywords

aminoglycoside nomograms; Bayesian; computerized dose prediction; gentamicin; pharmacokinetic methods

Indexed keywords

CREATININE; GENTAMICIN;

ACCURACY; ADULT; AGED; ALGORITHM; ANTIBIOTIC THERAPY; AREA UNDER THE CURVE; ARTICLE; BACTERIAL INFECTION; BAYESIAN LEARNING; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG MONITORING; FEBRILE NEUTROPENIA; FEMALE; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; NOMOGRAM; PRACTICE GUIDELINE; PREDICTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RETROSPECTIVE STUDY; SAWCHUK ZASKE METHOD;

ADOLESCENT; ADULT; AGED; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG MONITORING; FEMALE; GENTAMICINS; HALF-LIFE; HUMANS; MALE; MIDDLE AGED; NEUTROPENIA; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; TIME FACTORS; YOUNG ADULT;

EID: 80053568655     PISSN: 01634356     EISSN: 15363694     Source Type: Journal    
DOI: 10.1097/FTD.0b013e31822c78e9     Document Type: Article

References (39)

1. Begg EJ, Barclay ML. Aminoglycosides-50 years on. Br J Clin Pharmacol. 1995;39:597-603.
2. Barclay ML, Begg EJ, Hickling KG. What is the evidence for once-daily aminoglycoside therapy? Clin Pharmacokinet. 1994;27:32-48. (Pubitemid 24211095)
3. Barza M, Ioannidis JP, Cappelleri JC, et al. Single or multiple daily doses of aminoglycoside: a meta-analysis. BMJ. 1996;312:338-344.
4. Freeman CD, Strayer AH. Mega-analysis of meta-analysis: an examination of meta-analysis with an emphasis on once-daily aminoglycoside comparative trials. Pharmacotherapy. 1996;16:1093-1102. (Pubitemid 26403652)
5. Hatala R, Dinh T, Cook DJ. Once-daily aminoglycoside dosing in immunocompetent adults: a meta analysis. Ann Intern Med. 1996;124:717-725.
6. Munckhof WJ, Grayson ML, Turnidge JD. A meta-analysis of studies on the safety and efficacy of aminoglycosides given either as once-daily or as divided doses. J Antimicrob Chemother. 1996;37:645-663. (Pubitemid 26134115)
7. Prins JM, Buller HR, Huijper EJ, et al. Once versus thrice daily gentamicin in patients with serious infections. Lancet. 1993;341:335-339. (Pubitemid 23039700)
8. Moore RD, Lietman PS, Smith CR. Clinical response to aminoglycoside therapy: importance of the ratio of peak concentrations to minimal inhibitory concentration. J Infect Dis. 1987;155:93-99. (Pubitemid 17225088)
9. Nicolau DP, Freeman CD, Belliveau PP, et al. Experience with a oncedaily aminoglycoside program administered to 2,184 adult patients. Antimicrob Agents Chemother. 1995;39:650-655.
10. Zhanel GG, Hoban DJ, Harding GKM. The postantibiotic effect: a review of in-vitro and in-vivo data. Ann Pharmacother. 1991;25:153-163.
11. Wallace AW, Jones M, Bertino JS. Evaluation of four once-daily aminoglycoside dosing nomograms. Pharmacotherapy. 2002;22:1077-1083. (Pubitemid 34969059)
12. Aiken SK, Wetzstein GA. Once-daily aminoglycosides in patients with neutropaenic fever. Cancer Control. 2002;9:426-431. (Pubitemid 35204464)
13. Nicolau DP, Wu AH, Finocchiaro S, et al. Once-daily aminoglycoside dosing: impact on requests and costs for therapeutic drug monitoring. Ther Drug Monit. 1996;18:263-266. (Pubitemid 26159577)
14. Hughes WT, Armstrong D, Bodey GP, et al. 2002 guidelines for the use of antimicrobial agents in neutropaenic patients with cancer. Clin Infect Dis. 2002;34:730-751. (Pubitemid 34194843)
15. Rolston KVI, Tarrand JJ. Pseudomonas aeruginosa-still a frequent pathogen in patients with cancer: 11-year experience at a comprehensive cancer centre. Clin Infect Dis. 1999;29:463-464. (Pubitemid 29380232)
16. Paul M, Soares-Weiser K, Leibovici L. ß lacatam momotherapy versus ß lacatam-aminoglycoside combination therapy for fever with neutropaenia: systematic review and meta-analysis. BMJ. 2003;326:1-9.
17. Duffull SB, Kirkpatrick CMJ, Begg EJ. Comparison of two Bayesian approaches to dose-individualization for once-daily aminoglycoside regimens. Br J Clin Pharmacol. 1997;43:125-135. (Pubitemid 27085363)
18. Schentag JJ, Meagher AK, Jelliffe RW. Aminoglycosides. In: Burton ME, Shaw LM, Schentag JJ, et al, eds. Applied Pharmacokinetics and Pharmacodynamics: Principles of Therapeutic Drug Monitoring. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2006:285-327.
19. Therapeutic Guidelines: Antibiotics. 12th ed. North Melbourne, Australia: Therapeutic Guidelines Limited; 2003.
20. Nicolau DP, Belliveau PP, Nightingale CH, et al. Implementation of a once-daily aminoglycoside program in a large community-teaching hospital. Hosp Pharm. 1995;30:674-676, 679-680.
21. McNamara DR, Nafziger AN, Menhinick AM, et al. A dose ranging study of gentamicin pharmacokinetics: implications for extended dosing interval aminoglycoside therapy. J Clin Pharmacol. 2001;41:374-377. (Pubitemid 32274980)
22. Paterson DL, Robson JM, Wagener MM, et al. Monitoring of serum aminoglycoside levels with once-daily dosing. Pathology. 1998;30: 289-294.
23. Mohan M, Batty KT, Cooper JA, et al. Comparison of gentamicin dose estimates derived from manual calculations, the Australian therapeutic guidelines: antibiotic nomogram and the SEBAGEN and DOSECalc software programs. Br J Clin Pharmacol. 2004;58:521-527. (Pubitemid 39540456)
24. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16:31-41.
25. Devine BJ. Gentamicin therapy. Drug Intell Clin Pharm. 1974;8:650-655.
26. Kirkpatrick CMJ, Duffull SB, Begg EJ. Pharmacokinetics of gentamicin in 957 patients with varying renal function dosed once daily. Br J Clin Pharmacol. 1999;47:637-643. (Pubitemid 29257661)
27. Begg EJ, Barclay ML, Kirkpatrick CJM. The therapeutic monitoring of antimicrobial agents. Br J Clin Pharmacol. 1999;47:23-30. (Pubitemid 29043160)
28. Pesola GR, Akhavan I, Madfu A, et al. Prediction equation estimates of creatinine clearance in the intensive care unit. Intensive Care Med. 1993; 19:39-43. (Pubitemid 23081483)
29. Matthews I, Kirkpatrick C, Holford N. Quantitative justification for target concentration intervention-parameter variability and predictive performance using population pharmacokinetic models for aminoglycosides. Br J Clin Pharmacol. 2003;58:8-19. (Pubitemid 38901461)
30. Sheiner LB, Beal SL. Some suggestions for measuring predictive performance. J Pharmacokinet Biopharm. 1981;9:503-512.
31. Burton ME, Chow MS, Platt DR, et al. Accuracy of Bayesian and Sawchuk-Zaske dosing methods for gentamicin. Clin Pharm. 1986;5: 143-149. (Pubitemid 16161011)
32. Bertino JS, Booker LA, Franck P, et al. Gentamicin pharmacokinetics in patients with malignancies. Antimicrob Agents Chemother. 1991;35: 1501-1503.
33. Bianco TM, Dwyer PN, Bertino JS. Gentamicin pharmacokinetics, nephrotoxicity, and prediction of mortality in febrile neutropaenic patients. Antimicrob Agents Chemother. 1989;33:1890-1895. (Pubitemid 19266250)
34. Higa GM, Murray WE. Alterations in aminoglycosides pharmacokinetics with cancer. Clin Pharm. 1987;6:963-966.
35. MacGowan AP, Bedford KA, Blundell E, et al. The pharmacokinetics of once daily gentamicin in neutropaenic adults with haematological malignancy. J Antimicrob Chemother. 1994;34:809-812.
36. Manny RP, Hutson PR. Aminoglycoside volume of distribution in hematology-oncology patients. Clin Pharm. 1986;5:629-632.
37. Peterson AK, Duffull SB. Population analysis of once-daily dosing of gentamicin in patients with neutropaenia. Aust N Z J Med. 1998;28: 311-315. (Pubitemid 28322355)
38. Zeitany RG, El Saghir NS, Santhosh-Kumar CR, et al. Increased aminoglycoside dosage requirements in hematologic malignancy. Antimicrob Agents Chemother. 1990;34:702-708. (Pubitemid 20142384)
39. Sawchuk RJ, Zaske DE. Pharmacokinetics of dosing regimens which utilize multiple intravenous infusions: gentamicin in burn patients. J Pharmacokinet Biopharm. 1976;4:183-195. (Pubitemid 8133359)