Quantitative justification for target concentration intervention - Parameter variability and predictive performance using population pharmacokinetic models for aminoglycosides

British Journal of Clinical Pharmacology

Volumn 58, Issue 1, 2004, Pages 8-19

  Matthews, Ivan ^a   Kirkpatrick, Carl ^b   Holford, Nicholas ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Aminoglycosides; Pharmacokinetics; Population; Target concentration intervention

Indexed keywords

AMINOGLYCOSIDE DERIVATIVE;

ADULT; ARTICLE; BODY WEIGHT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; COVARIANCE; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DATA ANALYSIS; DOSE CALCULATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG RESEARCH; DRUG TARGETING; FEASIBILITY STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; PARAMETER; PERFORMANCE; POPULATION RESEARCH; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RANDOMIZATION; SEX DIFFERENCE; TECHNIQUE;

ADULT; AGED; AGING; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BODY WEIGHT; CREATININE; FEMALE; GENTAMICINS; HUMANS; KIDNEY; MALE; MIDDLE AGED; MODELS, CHEMICAL; PREDICTIVE VALUE OF TESTS; TOBRAMYCIN;

EID: 3142628301     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2004.02114.x     Document Type: Article

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