Structure and remodeling behavior of drug-loaded high density lipoproteins and their atherosclerotic plaque targeting mechanism in foam cell model

International Journal of Pharmaceutics

Volumn 419, Issue 1-2, 2011, Pages 314-321

  Zhang, Wen Li ^a   Xiao, Yan ^a   Liu, Jian Ping ^a   Wu, Zi Mei ^b   Gu, Xiao ^a   Xu, Yi Ming ^c   Lu, Hui ^c  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Atherosclerotic plaque targeting; Discoidal rHDL; Foam cells; Reconstituted high density lipoproteins; Spherical rHDL

Indexed keywords

CHOLESTEROL ESTER; GUANIDINE; HIGH DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE; TANSHINONE IIA; TRIOLEIN; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ARTICLE; ATHEROSCLEROTIC PLAQUE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STRUCTURE; DRUG TARGETING; DRUG UPTAKE; FOAM CELL; IN VITRO STUDY; LIPOPHILICITY; MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; ZETA POTENTIAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CHOLESTEROL ESTERS; DITERPENES, ABIETANE; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GUANIDINE; LIPOPROTEINS; LIPOPROTEINS, HDL; MACROPHAGES; MICE; MODELS, BIOLOGICAL; NANOPARTICLES; PHAGOCYTOSIS; PLAQUE, ATHEROSCLEROTIC; TRIOLEIN;

EID: 80053564286     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.07.039     Document Type: Article

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