메뉴 건너뛰기




Volumn 6, Issue 3, 2011, Pages 215-221

Effects of ranolazine on cardiovascular system

Author keywords

Angina pectoris; Atrial fibrillation; Coronary disease; Ranolazine

Indexed keywords

AMIODARONE; AMLODIPINE; ATENOLOL; CARDIAC GLYCOSIDE; DILTIAZEM; ENALAPRIL; ION CHANNEL; METOPROLOL; PLACEBO; RANOLAZINE;

EID: 80053550196     PISSN: 15748901     EISSN: None     Source Type: Journal    
DOI: 10.2174/157489011797377103     Document Type: Article
Times cited : (6)

References (55)
  • 1
    • 0037221387 scopus 로고    scopus 로고
    • ACC/AHA 2002 guideline update for the management of patients with chronic stable angina: A report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee to update the 1999 guidelines for the management of patients with chronic stable angina)
    • Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS, et al. ACC/AHA 2002 guideline update for the management of patients with chronic stable angina: A report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee to update the 1999 guidelines for the management of patients with chronic stable angina). J Am Coll Cardiol 2003; 41(1):159-68.
    • (2003) J Am Coll Cardiol , vol.41 , Issue.1 , pp. 159-168
    • Gibbons, R.J.1    Abrams, J.2    Chatterjee, K.3    Daley, J.4    Deedwania, P.C.5    Douglas, J.S.6
  • 2
    • 33644849222 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2006 update: A report from the American Heart Association statistics committee and stroke statistics subcommittee
    • Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T, et al. Heart disease and stroke statistics-2006 update: A report from the American Heart Association statistics committee and stroke statistics subcommittee. Circulation 2006; 113: e85-e151.
    • (2006) Circulation , vol.113 , pp. 85-151
    • Thom, T.1    Haase, N.2    Rosamond, W.3    Howard, V.J.4    Rumsfeld, J.5    Manolio, T.6
  • 3
    • 0036847929 scopus 로고    scopus 로고
    • Angina 1 year after percutaneous coronary intervention: A report from the NHLBI dynamic registry
    • Holubkov R, Laskey WK, Haviland A, Slater JC, Bourassa MG, Vlachos HA, et al. Angina 1 year after percutaneous coronary intervention: A report from the NHLBI dynamic registry. Am Heart J 2002; 144:826-833.
    • (2002) Am Heart J , vol.144 , pp. 826-833
    • Holubkov, R.1    Laskey, W.K.2    Haviland, A.3    Slater, J.C.4    Bourassa, M.G.5    Vlachos, H.A.6
  • 4
    • 0035849152 scopus 로고    scopus 로고
    • For the arterial revascularization therapies study group. Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease
    • Serruys PW, Unger F, Sousa JE, Jatene A, Bonnier HJ, Schönberger JP, et al. For the arterial revascularization therapies study group. Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease. N Engl J Med 2001; 344: 1117-24.
    • (2001) N Engl J Med , vol.344 , pp. 1117-1124
    • Serruys, P.W.1    Unger, F.2    Sousa, J.E.3    Jatene, A.4    Bonnier, H.J.5    Schönberger, J.P.6
  • 5
    • 8044240301 scopus 로고    scopus 로고
    • Five-year clinical and functional outcome comparing bypass surgery and angioplasty in patients with multivessel coronary disease: A multicenter randomized trial
    • Writing Group for the Bypass Angioplasty Revascularization Investigation (BARI) Investigators
    • Writing Group for the Bypass Angioplasty Revascularization Investigation (BARI) Investigators. Five-year clinical and functional outcome comparing bypass surgery and angioplasty in patients with multivessel coronary disease: A multicenter randomized trial. JAMA 1997; 277: 715-721.
    • (1997) JAMA , vol.277 , pp. 715-721
  • 7
    • 0033603311 scopus 로고    scopus 로고
    • Sodium regulation during ischemia versus reperfusion and its role in injury
    • Murphy E, Cross H, Steenbergen C. Sodium regulation during ischemia versus reperfusion and its role in injury. Circ Res 1999; 84: 1469-1470.
    • (1999) Circ Res , vol.84 , pp. 1469-1470
    • Murphy, E.1    Cross, H.2    Steenbergen, C.3
  • 8
    • 33144470708 scopus 로고    scopus 로고
    • Inhibition of late (sustained/ persistent) sodium current: A potential drug target to reduce intracellular sodium-dependent calcium overload and its detrimental effects on cardiomyocyte function
    • Belardinelli L, Antzelevitch C, Fraser H. Inhibition of late (sustained/ persistent) sodium current: A potential drug target to reduce intracellular sodium-dependent calcium overload and its detrimental effects on cardiomyocyte function. Eur Heart J. 2004; 6(Suppl I): 13-17.
    • (2004) Eur Heart J , vol.6 , Issue.SUPPL. I , pp. 13-17
    • Belardinelli, L.1    Antzelevitch, C.2    Fraser, H.3
  • 9
    • 79955418005 scopus 로고    scopus 로고
    • Emerging clinical role of ranolazine in the management of angina
    • Vadnais DS, Wenger NK. Emerging clinical role of ranolazine in the management of angina. Ther Clin Risk Manag 2010; 6: 517-530.
    • (2010) Ther Clin Risk Manag , vol.6 , pp. 517-530
    • Vadnais, D.S.1    Wenger, N.K.2
  • 10
    • 0030032681 scopus 로고    scopus 로고
    • Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts
    • McCormack JG, Barr RL, Wolff AA, Lopaschuk GD. Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts. Circulation 1996; 93(1): 135-142.
    • (1996) Circulation , vol.93 , Issue.1 , pp. 135-142
    • McCormack, J.G.1    Barr, R.L.2    Wolff, A.A.3    Lopaschuk, G.D.4
  • 11
    • 0141723313 scopus 로고    scopus 로고
    • The antianginal agent trimetazidine does not exert its functional benefit via inhibition of mitochondrial long-chain 3-ketoacyl coenzyme A thiolase
    • MacInnes A, Fairman DA, Binding P, Rhodes J, Wyatt MJ, Phelan A, et al. The antianginal agent trimetazidine does not exert its functional benefit via inhibition of mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circ Res 2003; 93(3): e26-e32.
    • (2003) Circ Res , vol.93 , Issue.3 , pp. 26-32
    • Macinnes, A.1    Fairman, D.A.2    Binding, P.3    Rhodes, J.4    Wyatt, M.J.5    Phelan, A.6
  • 12
    • 31644438932 scopus 로고    scopus 로고
    • The mechanism of ranolazine action to reduce ischemia-induced diastolic dysfunction
    • Belardinelli L, Shyrock JC, Fraser H. The mechanism of ranolazine action to reduce ischemia-induced diastolic dysfunction. Eur Heart J Suppl 2006; 8 (Suppl): A10-A13.
    • (2006) Eur Heart J Suppl , vol.8 , Issue.SUPPL , pp. 10-13
    • Belardinelli, L.1    Shyrock, J.C.2    Fraser, H.3
  • 13
    • 33947431938 scopus 로고    scopus 로고
    • A comparison between ranolazine and CVT-4325, a novel inhibitor of fatty acid oxidation, on cardiac metabolism and left ventricular function in rat isolated perfused heart during ischemia and reperfusion
    • Wang P, Fraser H, Lloyd SG, McVeigh JJ, Belardinelli L, Chatham JC. A comparison between ranolazine and CVT-4325, a novel inhibitor of fatty acid oxidation, on cardiac metabolism and left ventricular function in rat isolated perfused heart during ischemia and reperfusion. J Pharmacol Exp Ther 2007; 321: 213-220.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 213-220
    • Wang, P.1    Fraser, H.2    Lloyd, S.G.3    McVeigh, J.J.4    Belardinelli, L.5    Chatham, J.C.6
  • 14
    • 4344577023 scopus 로고    scopus 로고
    • Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties
    • Antzelevitch C, Belardinelli L, Zygmunt AC, Burashnikov A, Di Diego JM, Fish JM, et al. Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties. Circulation 2004; 110(8): 904-910.
    • (2004) Circulation , vol.110 , Issue.8 , pp. 904-910
    • Antzelevitch, C.1    Belardinelli, L.2    Zygmunt, A.C.3    Burashnikov, A.4    Di Diego, J.M.5    Fish, J.M.6
  • 15
    • 77956535593 scopus 로고    scopus 로고
    • The anti-ischemic mechanism of action of ranolazine in stable ischemic heart disease
    • Stone PH, Chaitman BR, Stocke K, Sano J, DeVault A, Koch GG. The anti-ischemic mechanism of action of ranolazine in stable ischemic heart disease. J Am Coll Cardiol 2010; 56(12): 934-942.
    • (2010) J Am Coll Cardiol , vol.56 , Issue.12 , pp. 934-942
    • Stone, P.H.1    Chaitman, B.R.2    Stocke, K.3    Sano, J.4    Devault, A.5    Koch, G.G.6
  • 16
    • 12844280008 scopus 로고    scopus 로고
    • Comparative efficacy of ranolazine versus atenolol for chronic angina pectoris
    • Rousseau MF, Pouleur H, Cocco G, Wolff AA. Comparative efficacy of ranolazine versus atenolol for chronic angina pectoris. Am J Cardiol 2005; 95: 311-336.
    • (2005) Am J Cardiol , vol.95 , pp. 311-336
    • Rousseau, M.F.1    Pouleur, H.2    Cocco, G.3    Wolff, A.A.4
  • 17
    • 11144356285 scopus 로고    scopus 로고
    • Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina
    • Chaitman BR, Skettino SL, Parker JO, Hanley P, Meluzin J, Kuch J, et al. Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina. J Am Coll Cardiol 2004; 43(8): 1375-1382.
    • (2004) J Am Coll Cardiol , vol.43 , Issue.8 , pp. 1375-1382
    • Chaitman, B.R.1    Skettino, S.L.2    Parker, J.O.3    Hanley, P.4    Meluzin, J.5    Kuch, J.6
  • 18
    • 0348129532 scopus 로고    scopus 로고
    • Combination Assessment of Ranolazine In Stable Angina (CARISA) investigators. Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina. A randomized controlled trial
    • Chaitman BR, Pepine CJ, Parker JO, Skopal J, Chumakova G, Kuch J, et al. Combination Assessment of Ranolazine In Stable Angina (CARISA) investigators. Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina. A randomized controlled trial. JAMA 2004; 291: 309-316.
    • (2004) JAMA , vol.291 , pp. 309-316
    • Chaitman, B.R.1    Pepine, C.J.2    Parker, J.O.3    Skopal, J.4    Chumakova, G.5    Kuch, J.6
  • 19
    • 33746192571 scopus 로고    scopus 로고
    • ERICA investigators. Antianginal effects of ranolazine when added to treatment with amlodipine: The ERICA (Efficiency of Ranolazine in Chronic Angina) trial
    • Stone PH, Gratsiansky NA, Blokhin A, Huang IZ, Meng L. ERICA investigators. Antianginal effects of ranolazine when added to treatment with amlodipine: the ERICA (Efficiency of Ranolazine in Chronic Angina) trial. J Am Coll Cardiol 2006; 48: 566-75.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 566-575
    • Stone, P.H.1    Gratsiansky, N.A.2    Blokhin, A.3    Huang, I.Z.4    Meng, L.5
  • 20
    • 34247526904 scopus 로고    scopus 로고
    • MERLIN-TIMI Investigators. Effects of ranolazine on recurrent cardiovascular events in patients with non-ST-elevation acute coronary syndromes. The MERLINTIMI 36 randomized trial
    • Morrow DA, Scirica BM, Karwatowska-Prokopczuk E, Murphy SA, Budaj A, Varshavsky S, et al. MERLIN-TIMI Investigators. Effects of ranolazine on recurrent cardiovascular events in patients with non-ST-elevation acute coronary syndromes. The MERLINTIMI 36 randomized trial. JAMA 2007; 297: 1775-83.
    • (2007) JAMA , vol.297 , pp. 1775-1783
    • Morrow, D.A.1    Scirica, B.M.2    Karwatowska-Prokopczuk, E.3    Murphy, S.A.4    Budaj, A.5    Varshavsky, S.6
  • 21
    • 64649089888 scopus 로고    scopus 로고
    • Efficacy of ranolazine in patients with chronic angina: Observations from the randomized, doubleblind, placebo-controlled MERLIN-TIMI (metabolic efficiency with ranolazine for less ischemia in non-ST-segment elevation acute coronary syndromes) 36 trial
    • Wilson SR, Scirica BM, Braunwald E, Murphy SA, Karwatowska- Prokopczuk E, Buros JL, et al. Efficacy of ranolazine in patients with chronic angina: Observations from the randomized, doubleblind, placebo-controlled MERLIN-TIMI (metabolic efficiency with ranolazine for less ischemia in non-ST-segment elevation acute coronary syndromes) 36 trial. J Am Coll Cardiol 2009; 53: 1510-6.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1510-1516
    • Wilson, S.R.1    Scirica, B.M.2    Braunwald, E.3    Murphy, S.A.4    Karwatowska- prokopczuk, E.5    Buros, J.L.6
  • 22
    • 44949176560 scopus 로고    scopus 로고
    • An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes
    • Song Y, Shryock JC, Belardinelli L. An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes. Am J Physiol Heart Circ Physiol 2008; 294:H2031-H2209.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294 , pp. 2031-2209
    • Song, Y.1    Shryock, J.C.2    Belardinelli, L.3
  • 24
    • 78751629468 scopus 로고    scopus 로고
    • The antianginal agent ranolazine is a potent antiarrhythmic agent that reduces ventricular arrhythmias: Through a mechanism favoring inhibition of late sodium channel
    • Kloner RA, Dow JS, Bhandari A. The antianginal agent ranolazine is a potent antiarrhythmic agent that reduces ventricular arrhythmias: Through a mechanism favoring inhibition of late sodium channel. Cardiovasc Ther 2010.
    • (2010) Cardiovasc Ther
    • Kloner, R.A.1    Dow, J.S.2    Bhandari, A.3
  • 25
    • 70449090162 scopus 로고    scopus 로고
    • Ranolazine, an antianginal agent, markedly reduces ventricular arrhythmias induced by ischemia and ischemiareperfusion
    • Dhalla AK, Wang WQ, Dow J, Shryock JC, Belardinelli L, Bhandari A, et al. Ranolazine, an antianginal agent, markedly reduces ventricular arrhythmias induced by ischemia and ischemiareperfusion. Am J Physiol Heart Circ Physiol 2009; 297(5): H1923-H1929.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297 , Issue.5 , pp. 1923-1929
    • Dhalla, A.K.1    Wang, W.Q.2    Dow, J.3    Shryock, J.C.4    Belardinelli, L.5    Bhandari, A.6
  • 26
    • 70350219094 scopus 로고    scopus 로고
    • Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation
    • Antzelevitch C, Burashnikov A. Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation. J Electrocardiol 2009; 42(6): 543-548.
    • (2009) J Electrocardiol , vol.42 , Issue.6 , pp. 543-548
    • Antzelevitch, C.1    Burashnikov, A.2
  • 27
    • 34748873780 scopus 로고    scopus 로고
    • Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: Differences in sodium channel inactivation between atria and ventricles and the role of ranolazine
    • Burashnikov A, Di Diego JM, Zygmunt AC, Belardinelli L, Antzelevitch C. Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: Differences in sodium channel inactivation between atria and ventricles and the role of ranolazine. Circulation 2007; 116(13): 1449-1457.
    • (2007) Circulation , vol.116 , Issue.13 , pp. 1449-1457
    • Burashnikov, A.1    Di Diego, J.M.2    Zygmunt, A.C.3    Belardinelli, L.4    Antzelevitch, C.5
  • 28
    • 73249135820 scopus 로고    scopus 로고
    • The use of oral ranolazine to convert new or paroxysmal atrial fibrillation: A review of experience with implications for possible "pill in the pocket" approach to atrial fibrillation
    • Murkock DK, Kersten M, Kaliebe J, Larrain G. The use of oral ranolazine to convert new or paroxysmal atrial fibrillation: A review of experience with implications for possible "pill in the pocket" approach to atrial fibrillation. Indian Pacing Electrophysiol J 2009; 9: 260-267
    • (2009) Indian Pacing Electrophysiol J , vol.9 , pp. 260-267
    • Murkock, D.K.1    Kersten, M.2    Kaliebe, J.3    Larrain, G.4
  • 29
  • 31
    • 0034971048 scopus 로고    scopus 로고
    • Late sodium current is a novel target for amiodarone: Studies in failing human myocardium
    • Maltsev VA, Sabbah HN, Undrovinas AI. Late sodium current is a novel target for amiodarone: Studies in failing human myocardium. J Mol Cell Cardiol 2001; 33: 923.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 923
    • Maltsev, V.A.1    Sabbah, H.N.2    Undrovinas, A.I.3
  • 32
    • 53049104215 scopus 로고    scopus 로고
    • Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long QT syndrome
    • Moss AJ, Zareba W, Schwarz KQ, Rosero S, McNitt S, Robinson JL. Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long QT syndrome. J Cardiovasc Electrophysiol 2008; 19: 1289-1293.
    • (2008) J Cardiovasc Electrophysiol , vol.19 , pp. 1289-1293
    • Moss, A.J.1    Zareba, W.2    Schwarz, K.Q.3    Rosero, S.4    McNitt, S.5    Robinson, J.L.6
  • 33
    • 35148850168 scopus 로고    scopus 로고
    • Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non-ST-segment elevation acute coronary syndrome: Results from the metabolic efficiency with ranolazine for less ischemia in non-ST-elevation acute coronary syndrome- thrombolysis in myocardial infarction 36 (MERLIN-TIMI 36) randomized controlled trial
    • Scirica BM, Morrow DA, Hod H, Murphy SA, Belardinelli L, Hedgepeth CM, et al. Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non-ST-segment elevation acute coronary syndrome: Results from the metabolic efficiency with ranolazine for less ischemia in non-ST-elevation acute coronary syndrome- thrombolysis in myocardial infarction 36 (MERLIN-TIMI 36) randomized controlled trial. Circulation 2007; 116: 1647-1652.
    • (2007) Circulation , vol.116 , pp. 1647-1652
    • Scirica, B.M.1    Morrow, D.A.2    Hod, H.3    Murphy, S.A.4    Belardinelli, L.5    Hedgepeth, C.M.6
  • 34
    • 14744290314 scopus 로고    scopus 로고
    • Increased late sodium current in myocytes from a canine heart failure and from failing human heart
    • Valdivia CR, Chu WW, Pu J, Foell JD, Haworth RA, Wolff MR, et al. Increased late sodium current in myocytes from a canine heart failure and from failing human heart. J Mol Cell Cardiol 2005; 38:475-483.
    • (2005) J Mol Cell Cardiol , vol.38 , pp. 475-483
    • Valdivia, C.R.1    Chu, W.W.2    Pu, J.3    Foell, J.D.4    Haworth, R.A.5    Wolff, M.R.6
  • 36
    • 33847261532 scopus 로고    scopus 로고
    • Undrovinas AI. Chronic heart failure slows late sodium current in human and canine ventricular myocytes: Implications for repolarization variability
    • Maltsev VA, Silverman N, Sabbah HN, Undrovinas AI. Chronic heart failure slows late sodium current in human and canine ventricular myocytes: Implications for repolarization variability. Eur J Heart Fail 2007; 9: 219-227.
    • (2007) Eur J Heart Fail , vol.9 , pp. 219-227
    • Maltsev, V.A.1    Silverman, N.2    Sabbah, H.N.3
  • 37
    • 77956063496 scopus 로고    scopus 로고
    • Late sodium current contributes to diastolic cell Ca2+ accumulation in chronic heart failure
    • Undrovinas NA, Maltsev VA, Belardinelli L, Sabbah HN, Undrovinas A. Late sodium current contributes to diastolic cell Ca2+ accumulation in chronic heart failure. J Physiol Sci 2010; 60(4): 245-2457.
    • (2010) J Physiol Sci , vol.60 , Issue.4 , pp. 245-2457
    • Undrovinas, N.A.1    Maltsev, V.A.2    Belardinelli, L.3    Sabbah, H.N.4    Undrovinas, A.5
  • 38
    • 67651067954 scopus 로고    scopus 로고
    • The late Na+ current (INa) inhibitor ranolazine attenuates effects of palmitoyl-Lcarnitine to increase late INa and cause ventricular diastolic dysfunction
    • Wu Y, Song Y, Belardinelli L, Shryock JC. The late Na+ current (INa) inhibitor ranolazine attenuates effects of palmitoyl-Lcarnitine to increase late INa and cause ventricular diastolic dysfunction. J Pharmacol Exp Ther 2009; 330(2): 550-7.
    • (2009) J Pharmacol Exp Ther , vol.330 , Issue.2 , pp. 550-557
    • Wu, Y.1    Song, Y.2    Belardinelli, L.3    Shryock, J.C.4
  • 39
    • 33745251122 scopus 로고    scopus 로고
    • Blocking late sodium current reduces hydrogen peroxide induced arrhythmogenic activity and contractile dysfunction
    • Song Y, Shryock JC, Wagner S, Maier LS, Belardinelli L. Blocking late sodium current reduces hydrogen peroxide induced arrhythmogenic activity and contractile dysfunction. J Pharmacol Exp Ther 2006; 318(1): 214-222.
    • (2006) J Pharmacol Exp Ther , vol.318 , Issue.1 , pp. 214-222
    • Song, Y.1    Shryock, J.C.2    Wagner, S.3    Maier, L.S.4    Belardinelli, L.5
  • 40
    • 33745368556 scopus 로고    scopus 로고
    • Inhibition of the late sodium current as a potential cardioprotective principle: Effects of the late sodium current inhibitor ranolazine
    • Belardinelli L, Shryock JC, Fraser H. Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine. Heart. 2006; 92 (Suppl 4): iv6-iv14.
    • (2006) Heart , vol.92 , Issue.SUPPL. 4
    • Belardinelli, L.1    Shryock, J.C.2    Fraser, H.3
  • 41
    • 4344697195 scopus 로고    scopus 로고
    • Cardiac metabolism as a target for the treatment of heart failure
    • Taegtmeyer H. Cardiac metabolism as a target for the treatment of heart failure. Circulation 2004; 110(8): 894-896.
    • (2004) Circulation , vol.110 , Issue.8 , pp. 894-896
    • Taegtmeyer, H.1
  • 42
    • 0036936426 scopus 로고    scopus 로고
    • Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure
    • Sabbah HN, Chandler MP, Mishima T, Suzuki G, Chaudhry P, Nass O, et al. Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure. J Card Fail 2002; 8(6): 416-422.
    • (2002) J Card Fail , vol.8 , Issue.6 , pp. 416-422
    • Sabbah, H.N.1    Chandler, M.P.2    Mishima, T.3    Suzuki, G.4    Chaudhry, P.5    Nass, O.6
  • 43
    • 57049182027 scopus 로고    scopus 로고
    • Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure
    • Rastogi S, Sharov VG, Mishra S, Gupta RC, Blackburn B, Belardinelli L, et al. Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure. Am J Physiol Heart Circ Physiol 2008; 295(5): H2149-H2155.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295 , Issue.5 , pp. 2149-2155
    • Rastogi, S.1    Sharov, V.G.2    Mishra, S.3    Gupta, R.C.4    Blackburn, B.5    Belardinelli, L.6
  • 44
    • 0028134824 scopus 로고
    • Effects of ranolazine on left ventricular regional diastolic function in patients with ischemic heart disease
    • Hayashida W, van Eyll C, Rousseau MF, Pouleur H. Effects of ranolazine on left ventricular regional diastolic function in patients with ischemic heart disease. Cardiovasc Drugs Ther 1994; 8: 741-747.
    • (1994) Cardiovasc Drugs Ther , vol.8 , pp. 741-747
    • Hayashida, W.1    van Eyll, C.2    Rousseau, M.F.3    Pouleur, H.4
  • 45
    • 45549105581 scopus 로고    scopus 로고
    • Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts-role of late sodium current and intracellular ion accumulation
    • Sossalla S, Wagner S, Rasenack EC, Ruff H, Weber SL, Schöndube FA, et al. Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts-role of late sodium current and intracellular ion accumulation. J Mol Cell Cardiol 2008; 45(1): 32-43.
    • (2008) J Mol Cell Cardiol , vol.45 , Issue.1 , pp. 32-43
    • Sossalla, S.1    Wagner, S.2    Rasenack, E.C.3    Ruff, H.4    Weber, S.L.5    Schöndube, F.A.6
  • 46
    • 33847385380 scopus 로고    scopus 로고
    • Long-term safety of a novel antianginal agent in patients with severe chronic stable angina: The Ranolazine Open Label Experience (ROLE)
    • Koren MJ, Crager MR, Sweeney M. Long-term safety of a novel antianginal agent in patients with severe chronic stable angina: The Ranolazine Open Label Experience (ROLE). J Am Coll Cardiol 2007; 49: 1027-1034.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1027-1034
    • Koren, M.J.1    Crager, M.R.2    Sweeney, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.