Improved retroviral suicide gene transfer in colon cancer cell lines after cell synchronization with methotrexate

Journal of Experimental and Clinical Cancer Research

Volumn 30, Issue 1, 2011, Pages

  Finzi, Laetitia ^a   Kraemer, Aurore ^a   Capron, Claude ^a   Noullet, Severine ^a   Goere, Diane ^a   Penna, Christophe ^a   Nordlinger, Bernard ^a   Legagneux, Josette ^b   Emile, Jean Fançois ^a   Malafosse, Robert ^a  

^a LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APHIDICOLIN; CYTARABINE; GANCICLOVIR; HERPES SIMPLEX VIRUS THYMIDINE KINASE; LIPOCORTIN 5; METHOTREXATE; RECOMBINANT ENZYME; RETROVIRUS VECTOR; THYMIDINE KINASE; UNCLASSIFIED DRUG; VIRUS ENZYME; ANTINEOPLASTIC ANTIMETABOLITE; ANTIVIRUS AGENT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GENE THERAPY; CELL CYCLE S PHASE; CELL SYNCHRONIZATION; COLON CANCER; FLOW CYTOMETRY; GENETIC TRANSDUCTION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SUICIDE GENE; VIRAL GENE DELIVERY SYSTEM; ANIMAL; CELL CYCLE; COLON TUMOR; CULTURE TECHNIQUE; DRUG EFFECT; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETICS; METABOLISM; MOUSE; RETROVIRUS; SIMPLEXVIRUS; TUMOR CELL CULTURE;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ANTIVIRAL AGENTS; APHIDICOLIN; APOPTOSIS; CELL CULTURE TECHNIQUES; CELL CYCLE; COLONIC NEOPLASMS; CYTARABINE; FLOW CYTOMETRY; GANCICLOVIR; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; METHOTREXATE; MICE; RETROVIRIDAE; SIMPLEXVIRUS; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

EID: 80053549512     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-30-92     Document Type: Article

References (39)

1. Gene therapy clinical trials worldwide to 2007 - an update. Edelstein ML, Abedi MR, Wixon J, J Gene Med 2007 9 833 842 10.1002/jgm.1100 17721874 (Pubitemid 47543250)
2. Progress and problems with the use of viral vectors for gene therapy. Thomas CE, Ehrhardt A, Kay MA, Nat Rev Genet 2003 4 346 358 10.1038/nrg1066 12728277 (Pubitemid 36538359)
3. Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses. Sandmair AM, Loimas S, Puranen P, Immonen A, Kossila M, Puranen M, Hurskainen H, Tyynela K, Turunen M, Vanninen R, Lehtolainen P, Paljarvi L, Johansson R, Vapalahti M, Yla-Herttuala S, Hum Gene Ther 2000 11 2197 2205 10.1089/104303400750035726 11084677
4. A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Rainov NG, Hum Gene Ther 2000 11 2389 2401 10.1089/104303400750038499 11096443
5. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Culver KW, Ram Z, Wallbridge S, Ishii H, Oldfield EH, Blaese RM, Science 1992 256 1550 1552 10.1126/science.1317968 1317968
6. Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]- guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1. Cheng YC, Huang ES, Lin JC, Mar EC, Pagano JS, Dutschman GE, Grill SP, Proc Natl Acad Sci USA 1983 80 2767 2770 10.1073/pnas.80.9.2767 6302704
7. E-cadherin contributes to the bystander effect of TK/GCV suicide therapy and enhances its antitumoral activity in pancreatic cancer models. Garcia-Rodriguez L, Abate-Daga D, Rojas A, Gonzalez JR, Fillat C, Gene Ther 2011 18 73 81 10.1038/gt.2010.114 20720574
8. Bystander effect in herpes simplex virus-thymidine kinase/ganciclovir cancer gene therapy: role of gap-junctional intercellular communication. Mesnil M, Yamasaki H, Cancer Res 2000 60 3989 3999 10945596 (Pubitemid 30636571)
9. Effect of herpes simplex virus thymidine kinase expression levels on ganciclovir-mediated cytotoxicity and the "bystander effect". Chen CY, Chang YN, Ryan P, Linscott M, McGarrity GJ, Chiang YL, Hum Gene Ther 1995 6 1467 1476 10.1089/hum.1995.6.11-1467 8573619
10. Establishment of parameters for optimal transduction efficiency and antitumor effects with purified high-titer HSV-TK retroviral vector in established solid tumors. Smiley WR, Laubert B, Howard BD, Ibanez C, Fong TC, Summers WS, Burrows FJ, Hum Gene Ther 1997 8 965 977 10.1089/hum.1997.8.8-965 9195219 (Pubitemid 27270159)
11. An optimal therapeutic expression level is crucial for suicide gene therapy for hepatic metastatic cancer in mice. Terazaki Y, Yano S, Yuge K, Nagano S, Fukunaga M, Guo ZS, Komiya S, Shirouzu K, Kosai K, Hepatology 2003 37 155 163 10.1053/jhep.2003.50018 12500200 (Pubitemid 36042156)
12. Regression of established macroscopic liver metastases after in situ transduction of a suicide gene. Caruso M, Panis Y, Gagandeep S, Houssin D, Salzmann JL, Klatzmann D, Proc Natl Acad Sci USA 1993 90 7024 7028 10.1073/pnas.90.15.7024 8346212 (Pubitemid 23222381)
13. A "distant" bystander effect of suicide gene therapy: regression of nontransduced tumors together with a distant transduced tumor. Kianmanesh AR, Perrin H, Panis Y, Fabre M, Nagy HJ, Houssin D, Klatzmann D, Hum Gene Ther 1997 8 1807 1814 10.1089/hum.1997.8.15-1807 9358030 (Pubitemid 27488930)
14. Evidence that retroviruses integrate into post-replication host DNA. Hajihosseini M, Iavachev L, Price J, Embo J 1993 12 4969 4974 8262039 (Pubitemid 23358485)
15. Retrovirus vector production and transduction: modulation by the cell cycle. Dolnikov A, Wotherspoon S, Millington M, Symonds G, J Gen Virol 2003 84 3131 3141 10.1099/vir.0.19099-0 14573819 (Pubitemid 37336798)
16. Integration of murine leukemia virus DNA depends on mitosis. Roe T, Reynolds TC, Yu G, Brown PO, Embo J 1993 12 2099 2108 8491198 (Pubitemid 23157725)
17. Cell cycle dependence of retroviral transduction: An issue of overlapping time scales. Andreadis S, Fuller AO, Palsson BO, Biotechnol Bioeng 1998 58 272 281 10.1002/(SICI)1097-0290(19980420)58:2/3<272::AID-BIT23>3.0.CO;2-D 10191401 (Pubitemid 28136388)
18. Infection efficiency of T lymphocytes with amphotropic retroviral vectors is cell cycle dependent. Springett GM, Moen RC, Anderson S, Blaese RM, Anderson WF, J Virol 1989 63 3865 3869 2788225 (Pubitemid 19205460)
19. Synchronisation of cancer cell lines of human origin using methotrexate. Sen S, Erba E, D'Incalci M, Cytometry 1990 11 595 602 10.1002/cyto.990110506 2379450 (Pubitemid 20195430)
20. Inhibition of Pgp activity and cell cycle-dependent chemosensitivity to doxorubicin in the multidrug-resistant LoVo human colon cancer cell line. Toffoli G, Corona G, Gigante M, Boiocchi M, Eur J Cancer 1996 32A 1591 1597 8911123 (Pubitemid 26279129)
21. Potentiation of etoposide cytotoxicity against a human ovarian cancer cell line by pretreatment with non-toxic concentrations of methotrexate or aphidicolin. Erba E, Sen S, Lorico A, D'Incalci M, Eur J Cancer 1992 28 66 71 10.1016/0959-8049(92)90387-H 1314631
22. Potentiation of etoposide-induced cytotoxicity and DNA damage in CCRF-CEM cells by pretreatment with non-cytotoxic concentrations of arabinosyl cytosine. Chresta CM, Hicks R, Hartley JA, Souhami RL, Cancer Chemother Pharmacol 1992 31 139 145 10.1007/BF00685101 1333370
23. Selective sensitization of transformed cells to flavopiridol-induced apoptosis following recruitment to S-phase. Matranga CB, Shapiro GI, Cancer Res 2002 62 1707 1717 11912144 (Pubitemid 34408493)
24. Cisplatin, vincristine, methotrexate, peplomycin, etoposide (COMPE) therapy for disseminated germ cell testicular tumors. Yoshimura K, Yamauchi T, Maeda H, Kawai T, Int J Urol 1997 4 47 51 10.1111/j.1442-2042.1997.tb00139.x 9179666 (Pubitemid 27129267)
25. A preclinical model of hepatocyte gene transfer: the in vivo, in situ perfused rat liver. De Godoy JL, Malafosse R, Fabre M, Mitchell C, Mehtali M, Houssin D, Soubrane O, Gene Ther 2000 7 1816 1823 10.1038/sj.gt.3301313 11110413
26. In vivo hepatocyte retrovirus-mediated gene transfer through the rat biliary tract. De Godoy JL, Malafosse R, Fabre M, Mehtali M, Houssin D, Soubrane O, Hum Gene Ther 1999 10 249 257 10.1089/10430349950019039 10022549 (Pubitemid 29070638)
27. Cell cycle analysis by flow cytometry. Gray JW, Coffino P, Methods Enzymol 1979 58 233 248 423764
28. Rapid identification and quantitation of cells infected by recombinant herpesvirus (pseudorabies virus) using a fluorescence-based beta-galactosidase assay and flow cytometry. Saalmuller A, Mettenleiter TC, J Virol Methods 1993 44 99 108 10.1016/0166-0934(93)90012-G 8227283
29. S- and G2-phase cell cycle arrests and apoptosis induced by ganciclovir in murine melanoma cells transduced with herpes simplex virus thymidine kinase. Wei SJ, Chao Y, Hung YM, Lin WC, Yang DM, Shih YL, Ch'ang LY, Whang-Peng J, Yang WK, Exp Cell Res 1998 241 66 75 10.1006/excr.1998.4005 9633514 (Pubitemid 28366580)
30. Retrovirus restriction revealed. Coffin JM, Nature 1996 382 762 763 10.1038/382762a0 8752269 (Pubitemid 26299547)
31. Moloney murine leukemia virus-derived retroviral vectors decay intracellularly with a half-life in the range of 5.5 to 7.5 hours. Andreadis ST, Brott D, Fuller AO, Palsson BO, J Virol 1997 71 7541 7548 9311834 (Pubitemid 27391695)
32. Characterization of an animal model of metastatic colon carcinoma. Dunnington DJ, Buscarino C, Gennaro D, Greig R, Poste G, Int J Cancer 1987 39 248 254 10.1002/ijc.2910390221 3804494 (Pubitemid 17015288)
33. Proliferation of the human colon carcinoma cell line HT29: autocrine growth and deregulated expression of the c-myc oncogene. Forgue-Lafitte ME, Coudray AM, Breant B, Mester J, Cancer Res 1989 49 6566 6571 2684395 (Pubitemid 20008788)
34. Methotrexate decreases thymidine kinase activity. Abonyi M, Prajda N, Hata Y, Nakamura H, Weber G, Biochem Biophys Res Commun 1992 187 522 528 10.1016/S0006-291X(05)81525-6 1520343
35. Time-dependent changes in H1 content, H1 turnover, DNA elongation, and the survival of cells blocked in early S phase by hydroxyurea, aphidicolin, or 5-fluorodeoxyuridine. D'Anna JA, Crissman HA, Jackson PJ, Tobey R, Biochemistry 1985 24 5020 5026 10.1021/bi00340a010 2934087 (Pubitemid 15242605)
36. Induction of partial synchronization of leukemia cells by continuous infusion of low-dose methotrexate followed by citrovorum factor. D'Incalci M, Erba E, Sen S, Rabbone ML, Perlangeli MV, Masera G, Conter V, J Natl Cancer Inst 1989 81 1509 1510 10.1093/jnci/81.19.1509 2674461 (Pubitemid 19252405)
37. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Miller DG, Adam MA, Miller AD, Mol Cell Biol 1990 10 4239 4242 2370865
38. Kinetics of retrovirus mediated gene transfer: the importance of intracellular half-life of retroviruses. Andreadis ST, Palsson BO, J Theor Biol 1996 182 1 20 10.1006/jtbi.1996.0140 8917734 (Pubitemid 26358720)
39. Thymidine and hypoxanthine requirements for the proliferation of normal and Rous sarcoma virus-infected chicken fibroblasts in the presence of methotrexate. Balk SD, Mitchell RS, LeStourgeon D, Hoon BS, Cancer Res 1979 39 1854 1856 218735 (Pubitemid 9171852)