Aromatase inhibitors in human lung cancer therapy

Cancer Research

Volumn 65, Issue 24, 2005, Pages 11287-11291

  Weinberg, Olga K ^a   Marquez Garban, Diana C ^a   Fishbein, Michael C ^a   Goodglick, Lee ^a   Garban, Hermes J ^a   Dubinett, Steven M ^a   Pietras, Richard J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANASTROZOLE; ANDROSTENEDIONE; AROMATASE; AROMATASE INHIBITOR; COMPLEMENTARY DNA; ESTRADIOL; ESTROGEN RECEPTOR; MESSENGER RNA; TESTOSTERONE; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER THERAPY; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; ISOTOPE LABELING; LUNG CANCER; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; WESTERN BLOTTING;

ANDROSTENEDIONE; ANIMALS; AROMATASE; AROMATASE INHIBITORS; CARCINOMA, NON-SMALL-CELL LUNG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; NITRILES; OVARIECTOMY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSPLANTATION, HETEROLOGOUS; TRIAZOLES;

EID: 29244469437     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-2737     Document Type: Article

References (20)

1. Patel JD, Bach PB, Kris MG. Lung cancer in US women: a contemporary epidemic. JAMA 2004;291:1763-8.
2. Taioli E, Wynder EL. Endocrine factors and adenocar cinoma of the lung in women. J Natl Cancer Inst 1994;86: 869-70.
3. Stabile LP, Davis ALG, Gubish CT, et al. Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor α and β and show biological responses to estrogen. Cancer Res 2002;62: 2141-50.
4. Patrone C, Cassel T, Pettersson K, et al. Regulation of postnatal lung development and homeostasis by estrogen receptor β. Mol Cell Biol 2003;23:8542-52.
5. Pietras RJ, Marquez DC, Chen H-W, Tsai E, Weinberg O, Fishbein M. Estrogen and growth factor receptor interactions in human breast and non-small cell lung cancer cells. Steroids 2005;70:372-81.
6. Beattie CW, Hansen NW, Thomas PA. Steroids receptors in human lung cancer. Cancer Res 1985;45: 4206-14.
7. Couse JF, Lindzey J, Grandien K, Gustafsson JA, Korach KS. Tissue distribution and quantitative analysis of estrogen receptor-α (ERα) and estrogen receptor-β (ERβ) messenger ribonucleic acid in the wild-type and ERα-knockout mouse. Endocrinology 1997;138:4613-21.
8. Kirsch EA, Yuhanna IS, Chen Z, German Z, Sherman TS, Shaul PW. Estrogen acutely stimulates endothelial nitric oxide synthase in H441 human airway epithelial cells. Am J Respir Cell Mol Biol 1999;20:658-66.
9. Mollerup S, Jorgensen K, Berge G, Haugen A. Expression of estrogen receptor α and β in human lung tissue and cell lines. Lung cancer 2002;37:153-9.
10. Kawai H, Ishii A, Washiya K, et al. Estrogen receptor α and β are prognostic factors in non-small cell lung cancer. Clin Cancer Res 2005;11:5084-9.
11. Pezzi V, Mathis JM, Rainey WE, Carr BR. Profiling transcript levels for steroidogenic enzymes in fetal tissues. J Steroid Biochem Mol Biol 2003;87:181-9.
12. Brodie A, Long B, Lu Q. Aromatase expression in the human breast. Breast Cancer Res Treat 1998;49:S85-91.
13. Pietras RJ, Arboleda J, Reese D, et al. HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells. Oncogene 1995;10:2435-46.
14. 2-dependent activation of nuclear factor κB. Role in sensitization of human tumor cells to tumor necrosis factor-α-induced cytotoxicity. J Biol Chem 2001;276: 8918-23.
15. Long BJ, Tilghman SL, Yue W, Thiantanawat A, Grigoryev DN, Brodie AM. The steroidal antiestrogen ICI 182,780 is an inhibitor of cellular aromatase activity. J Steroid Biochem Mol Biol 1998;67:293-304.
16. Kinoshita Y, Chen S. Induction of aromatase (CYP19) expression in breast cancer cells through a nongenomic action of estrogen receptor α. Cancer Res 2003;63:3546-55.
17. Lu Q, Nakmura J, Savinov A, et al. Expression of aromatase protein and messenger ribonucleic acid in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancers. Endocrinology 1996;137:3061-8.
18. Pegram MD, Finn RS, Arzoo K, Beryt M, Pietras RJ, Slamon DJ. The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells. Oncogene 1997;15: 537-47.
19. Stabile LP, Lyker JS, Gubish CT, Zhang W, Grandis JR, Siegfried JM. Combined targeting of estrogen receptor and epidermal growth factor receptor in non-small cell lung cancer shows enhanced antiproliferative effects. Cancer Res 2005;65:1459-70.
20. Mor G, Yue W, Santen RJ, et al. Macrophages, estrogen and the microenvironment of breast cancer. J Steroid Biochem Mol Biol 1998;67:403-11.