Structural, mechanistic, and computational analysis of the effects of anomeric fluorines on anomeric fluoride departure in 5-fluoroxylosyl fluorides

Journal of the American Chemical Society

Volumn 133, Issue 40, 2011, Pages 15826-15829

  Lee, Seung Seo ^a   Greig, Ian R ^a   Vocadlo, David J ^a   McCarter, John D ^a   Patrick, Brian O ^a   Withers, Stephen G ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANOMERICS; COMPUTATIONAL ANALYSIS; COMPUTATIONAL STUDIES; FIRST-ORDER RATE CONSTANTS; FLUORINE SUBSTITUTION; GLYCOSIDASES; GLYCOSYL; GROUND-STATE STRUCTURES; HYDROGEN BONDING INTERACTIONS; INTRINSIC REACTIVITY; MINIMAL EFFECTS; RATE REDUCTION; SPONTANEOUS HYDROLYSIS; STERIC EFFECT; X-RAY STRUCTURE;

FLUORINE; FLUORINE COMPOUNDS; HYDROGEN; HYDROGEN BONDS; SOLVENTS; STEREOCHEMISTRY;

RATE CONSTANTS;

5 FLUOROXYLOSYL FLUORIDE; ACETIC ACID DERIVATIVE; FLUORIDE; FLUORINE DERIVATIVE; GLYCOSIDASE; PYRANOSIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; HYDROGEN BOND; HYDROLYSIS; MOLECULAR INTERACTION; SOLVOLYSIS; STEREOCHEMISTRY; SUBSTITUTION REACTION; X RAY; X RAY SPECTROMETRY;

CRYSTALLOGRAPHY, X-RAY; FLUORIDES; FLUORINE; ISOMERISM; MODELS, MOLECULAR; XYLOSE;

EID: 80053528257     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja204829r     Document Type: Article

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