Quantification of Clostridium difficile in antibiotic-associated-diarrhea patients

Journal of Clinical Microbiology

Volumn 49, Issue 10, 2011, Pages 3656-3658

  Naaber, Paul ^a,b   Štšepetova, Jelena ^b   Smidt, Imbi ^b   Rätsep, Merle ^b   Kõljalg, Siiri ^b,c   Lõivukene, Krista ^c   Jaanimäe, Liis ^b   Löhr, Iren H ^a   Natås, Olav B ^a   Truusalu, Kai ^b   Sepp, Epp ^b  

^a STAVANGER UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF TARTU   (Estonia)

^c TARTU UNIVERSITY HOSPITAL   (Estonia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL DNA; BACTERIAL TOXIN;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC ASSOCIATED DIARRHEA; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM CULTURE; CHILD; CLINICAL ARTICLE; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DRUG INDUCED DISEASE; FECES ANALYSIS; FEMALE; HUMAN; MALE; MICROBIAL CONTAMINATION; NONHUMAN; PATHOGENESIS; PRESCHOOL CHILD; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTERIAL LOAD; BACTERIAL TOXINS; CHILD; CHILD, PRESCHOOL; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; DIARRHEA; FEMALE; HUMANS; MALE; MIDDLE AGED; SENSITIVITY AND SPECIFICITY; STATISTICS AS TOPIC; YOUNG ADULT;

CLOSTRIDIUM DIFFICILE;

EID: 80053492519     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.05115-11     Document Type: Article

References (17)

1. Åkerlund, T., B. Svenunhsson, Å. Lagergren, and L. G. Burman. 2006. Correlation of disease severity with fecal toxin levels in patients with Clostridium difficile-associated diarrhea and distribution of PCR ribotypes and toxin yields in vitro of corresponding isolates. J. Clin. Microbiol. 44:353-358. (Pubitemid 43222222)
2. Aslam, S., R. J. Hamill, and D. M. Musher. 2005. Treatment of Clostridium difficile-associated disease: old therapies and new strategies. Lancet Infect. Dis. 5:549-557. (Pubitemid 41196754)
3. Balamurugan, R., V. Balaji, and B. S. Ramakrishna. 2008. Estimation of faecal carriage of Clostridium difficile in patients with ulcerative colitis using real time polymerase chain reaction. Indian J. Med. Res. 127:472-477.
4. Crobach, M. J. T., O. M. Dekkers, M. H. Wilcox, and E. J. Kuijper. 2009. European Society of Clinical Microbiology and Infectious Diseases (ESCMID): data review and recommendations for diagnosing Clostridium difficile-infection (CDI). Clin. Microbiol. Infect. 15:1053-1066.
5. Gorkiewicz, G. 2009. Nosocomial and antibiotic-associated diarrhoea caused by organisms other than Clostridium difficile. Int. J. Antimicrob. Agents 33(Suppl.):S37-S41.
6. Guerrant, R. L., et al. 1992. Measurement of fecal lactoferrin as a marker of fecal leukocytes. J. Clin. Microbiol. 30:1238-1242.
7. Iizuka, M., et al. 2004. Novel evidence suggesting Clostridium difficile is present at human gut microflora more frequently than previously suspected. Microbiol. Immunol. 48:889-892. (Pubitemid 39602046)
8. Mangin, I., et al. 2006. Characterization of human intestinal bifidobacteria using competitive PCR and PCR-TGGE. FEMS Microbiol. Ecol. 55:28-37.
9. McFee, R. B., and G. G. Abdelsayed. 2009. Clostridium difficile. Dis. Mon. 55:439-470.
10. Mutters, R., et al. 2009. Quantitative detection of Clostridium difficile in hospital environmental samples by real-time polymerase chain reaction. J. Hosp. Infect. 71:43-48.
11. Penders, J., et al. 2006. Factors influencing the composition of the intestinal microbiota in elderly infancy. Pediatrics 118:511-521. (Pubitemid 46085405)
12. Penders, J., et al. 2005. Quantification of Bifidobacterium spp., Escherichia coli and Clostridium difficile in faecal samples of breast-fed and formula-fed infants by real-time PCR. FEMS Microbiol. Lett. 243:141-147. (Pubitemid 40164400)
13. Rinttilä, T., A. Kassinen, E. Malinen, L. Krogius, and A. Palva. 2004. Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR. J. Appl. Microbiol. 97:1166-1177. (Pubitemid 39573940)
14. Schleupner, M. A., et al. 1995. Concurrence of Clostridium difficile toxin A enzyme-linked immunosorbent assay, fecal lactoferrin assay, and clinical criteria with C. difficile cytotoxin titer in two patient cohorts. J. Clin. Microbiol. 33:1755-1759.
15. Sebaihia, M., et al. 2006. The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat. Genet. 38:779-786. (Pubitemid 43980598)
16. Steiner, T. S., C. A. Flores, T. I. Pizarro, and R. L. Guerrant. 1997. Fecal lactoferrin, interleukin-1β, and interleukin-8 are elevated in patients with severe Clostridium difficile colitis. Clin. Diagn. Lab. Immunol. 4:719-722. (Pubitemid 27501413)
17. Yong, W. H., A. R. Mattia, and M. J. Ferraro. 1994. Comparison of fecal lactoferrin latex agglutination assay and methylene blue microscopy for detection of fecal leukocytes in Clostridium difficile-associated disease. J. Clin. Microbiol. 32:1360-1361. (Pubitemid 24132577)