C-027 inhibits IgE-mediated passive sensitization bronchoconstriction and acts as a histamine and serotonin antagonist in human airways

Allergy and Asthma Proceedings

Volumn 32, Issue 5, 2011, Pages 359-365

  Cooper, Philip R ^a   Zhang, Jie ^a   Damera, Gautam ^a   Hoshi, Toshinori ^b   Zopf, David A ^c   Panettieri Jr , Reynold A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO N [2 [4 [3 (2 TRIFLUOROMETHYL PHENOTHIAZIN 10 YL)PROPYL]PIPERAZIN 1 YL]ETHYL]ACETAMIDE; ALLERGEN; ANTIHISTAMINIC AGENT; CALCIUM; FEXOFENADINE; G PROTEIN COUPLED RECEPTOR; HISTAMINE RECEPTOR; IMMUNOGLOBULIN E; SEROTONIN; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; BRAIN TISSUE; BRONCHOSPASM; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG RECEPTOR BINDING; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; SMOOTH MUSCLE CONTRACTION; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ACETAMIDES; ANIMALS; BIOLOGICAL AVAILABILITY; BRONCHIAL HYPERREACTIVITY; BRONCHOCONSTRICTION; CALCIUM; HISTAMINE; HISTAMINE ANTAGONISTS; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; MICE; PHENOTHIAZINES; RECEPTORS, HISTAMINE; RESPIRATORY SYSTEM; SEROTONIN ANTAGONISTS;

EID: 80053423166     PISSN: 10885412     EISSN: 15396304     Source Type: Journal    
DOI: 10.2500/aap.2011.32.3460     Document Type: Article

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