ARTICLE;
BREAST CANCER;
BREAST CARCINOGENESIS;
CANCER SIZE;
CANCER SURVIVAL;
CLINICAL FEATURE;
EXON;
GENE MUTATION;
PHENOTYPE;
POINT MUTATION;
PROGNOSIS;
PROTEIN EXPRESSION;
ADENOCARCINOMA;
ADOLESCENT;
ADULT;
AGED;
AGED, 80 AND OVER;
BREAST NEOPLASMS;
CARCINOMA, DUCTAL, BREAST;
CARCINOMA, LOBULAR;
CARCINOMA, MEDULLARY;
EXONS;
FEMALE;
FOLLOW-UP STUDIES;
HUMANS;
LYMPHATIC METASTASIS;
MIDDLE AGED;
PHOSPHATIDYLINOSITOL 3-KINASES;
POINT MUTATION;
RECEPTOR, ERBB-2;
RECEPTORS, ESTROGEN;
SURVIVAL RATE;
TUMOR BURDEN;
YOUNG ADULT;
Frequent mutation of the PIK3CA gene in ovarian and breast cancers
DOI 10.1158/1078-0432.CCR-04-2142
Levine DA, Bogomolniy F, Yee CJ, et al. Frequent mutation of the PIK3CA gene in ovarian and breast cancers. Clin Cancer Res, 2005, 11:2875-2878. (Pubitemid 40525186)
Early involvement of the phosphatidylinositol 3-kinase/Akt pathway in lung cancer progression
DOI 10.1164/rccm.200404-487OC
Massion PP, Taflan PM, Shyr Y, et al. Early involvement of the phosphatidylinositol 3-kinase/Akt pathway in lung cancer progression. Am J Respir Crit Care Med, 2004, 170:1088-1094. (Pubitemid 39488621)
PIK3CA exon 20 mutation is independently associated with a poor prognosis in breast cancer patients
Lai YL, Mau BL, Cheng WH, et al. PIK3CA exon 20 mutation is independently associated with a poor prognosis in breast cancer patients. Ann Surg Oncol, 2008, 15:1064-1069.
PIK3CA mutations and PTEN loss correlate with similar prognostic factors and are not mutually exclusive in breast cancer
DOI 10.1158/1078-0432.CCR-06-1609
Pérez-Tenorio G, Alkhori L, Olsson B, et al. PIK3CA mutations and PTEN loss correlate with similar prognostic factors and are not mutually exclusive in breast cancer. Clin Cancer Res, 2007, 13:3577-3584. (Pubitemid 46955118)
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
DOI 10.1038/sj.onc.1208304
Lee JW, Soung YH, Kim SY, et al. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas. Oncogene, 2005, 24:1477-1480. (Pubitemid 40343128)
Mutation of the PIK3CA gene in ovarian and breast cancer
DOI 10.1158/0008-5472.CAN-04-2933
Campbell IG, Russell SE, Choong DY, et al. Mutation of the PIK3CA gene in ovarian and breast cancer. Cancer Res, 2004, 64:7678-7681. (Pubitemid 39446895)
The PIK3CA gene is mutated with high frequency in human breast cancers
Bachman KE, Argani P, Samuels Y, et al. The PIK3CA gene is mutated with high frequency in human breast cancers. Cancer Biol Ther, 2004, 3:772-775. (Pubitemid 41351083)
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
Campbell RA, Bhat-Nakshatri P, Patel NM, et al. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem, 2001, 276:9817-9824.