A2780s; Akt PKB; Cells; Drug resistance; Neoplasm; OV2008; Ovarian neoplasms; P53 protein
Indexed keywords
CISPLATIN;
GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE;
LACTATE DEHYDROGENASE;
PROTEIN AKT1;
PROTEIN KINASE B;
PROTEIN KINASE B BETA;
PROTEIN P53;
SMALL INTERFERING RNA;
UNCLASSIFIED DRUG;
ANTINEOPLASTIC AGENT;
APOPTOSIS;
ARTICLE;
BIOACCUMULATION;
CANCER CELL CULTURE;
CANCER RESISTANCE;
DOWN REGULATION;
FEMALE;
GENETIC TRANSFECTION;
HUMAN;
HUMAN CELL;
MITOCHONDRION;
OVARY CANCER;
PROTEIN EXPRESSION;
PROTEIN LOCALIZATION;
STAINING;
WESTERN BLOTTING;
DRUG EFFECTS;
DRUG RESISTANCE;
GENETICS;
METABOLISM;
OVARIAN NEOPLASMS;
PHYSIOLOGY;
TUMOR CELL LINE;
ANTINEOPLASTIC AGENTS;
APOPTOSIS;
BLOTTING, WESTERN;
CELL LINE, TUMOR;
CISPLATIN;
DRUG RESISTANCE, NEOPLASM;
FEMALE;
HUMANS;
MITOCHONDRIA;
OVARIAN NEOPLASMS;
PROTO-ONCOGENE PROTEINS C-AKT;
RNA, SMALL INTERFERING;
TUMOR SUPPRESSOR PROTEIN P53;
Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: Possible involvement of the phosphoinositide-3 kinase/Akt pathway
DOI 10.1016/S1368-7646(02)00003-1, PII S1368764602000031
Cheng J Q, Jiang X, Fraser M, et al. Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway. Drug Resist Updat, 2002, 5:131-146. (Pubitemid 35033805)
Akt-mediated cisplatin resistance in ovarian cancer: Modulation of p53 action on caspase-dependent mitochondrial death pathway
Yang X, Fraser M, Moll UM, et al. Akt-mediated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway. Cancer Res, 2006, 66:3126-3136.
XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells
Asselin E, Mills GB, Tsang BK. XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells. Cancer Res, 2001, 61:1862-1868. (Pubitemid 32692000)
1- methyl ester integrated into lipid microspheres against human ovarian carcinoma cells resistant to cisplatin in vivo
Sasaki H, Niimi S, Akiyama M, et al. Antitumor activity of 13, 14-dihydro-15-deoxy-delta7-prostaglandin-A1-methyl ester integrated into lipid microspheres against human ovarian carcinoma cells resistant to cisplatin in vivo. Cancer Res, 1999, 59:3919-3922. (Pubitemid 29393553)
AKT2 inhibition of cisplatin-induced JNK/p38 and bax activation by phosphorylation of ASK1. Implication of AKT2 in chemoresistance
DOI 10.1074/jbc.M302674200
Yuan ZQ, Feldman RI, Sussman GE, et al. AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. J Biol Chem, 2003, 278:23432-23440. (Pubitemid 36830160)
Death signal-induced localization of p53 protein to mitochondria: A potential role in apoptotic signaling
DOI 10.1074/jbc.275.21.16202
Marchenko ND, Zaika A, Moll UM. Death signal-induced localization of p53 protein to mitochondria: a potential role in apoptotic signaling. J Biol Chem, 2000, 275:16202-16212. (Pubitemid 30366932)
