Epidermal growth factor-induced matrix metalloproteinase-1 expression is negatively regulated by p38 MAPK in human skin fibroblasts

Journal of Dermatological Science

Volumn 64, Issue 2, 2011, Pages 134-141

  Park, Chi Hyun ^a,b,c   Chung, Jin Ho ^a,b,c  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Seoul National University Hospital   (South Korea)

Author keywords

EGF; ERK; JNK; MMP 1; P38 MAPK

Indexed keywords

EPIDERMAL GROWTH FACTOR; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 11; MITOGEN ACTIVATED PROTEIN KINASE 12; MITOGEN ACTIVATED PROTEIN KINASE 13; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL VIABILITY; CHILD; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; SKIN FIBROBLAST; UPREGULATION; WESTERN BLOTTING;

CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 1; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 80053384728     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2011.07.002     Document Type: Article

References (41)

1. Melenhorst W.B., Mulder G.M., Xi Q., Hoenderop J.G., Kimura K., Eguchi S., et al. Epidermal growth factor receptor signaling in the kidney: key roles in physiology and disease. Hypertension 2008, 52:987-993.
2. Pastore S., Mascia F., Mariani V., Girolomoni G. The epidermal growth factor receptor system in skin repair and inflammation. J Invest Dermatol 2008, 128:1365-1374.
3. Fanger G.R., Johnson N.L., Johnson G.L. MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42. EMBO J 1997, 16:4961-4972.
4. Frey M.R., Dise R.S., Edelblum K.L., Polk D.B. p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration. EMBO J 2006, 25:5683-5692.
5. Grando S.A., Bystryn J.C., Chernyavsky A.I., Frusic-Zlotkin M., Gniadecki R., Lotti R., et al. Apoptolysis: a novel mechanism of skin blistering in pemphigus vulgaris linking the apoptotic pathways to basal cell shrinkage and suprabasal acantholysis. Exp Dermatol 2009, 18:764-770.
6. Nagase H., Woessner J.F. Matrix metalloproteinases. J Biol Chem 1999, 274:21491-21494.
7. Sternlicht M.D., Werb Z. How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 2001, 17:463-516.
8. Park M.J., Park J.H., Hahm S.H., Ko S.I., Lee Y.R., Chung J.H., et al. Repair activities of human 8-oxoguanine DNA glycosylase are stimulated by the interaction with human checkpoint sensor Rad9-Rad1-Hus1 complex. DNA Repair (Amst) 2009, 8:1190-1200.
9. Kahari V.M., Saarialho-Kere U. Matrix metalloproteinases in skin. Exp Dermatol 1997, 6:199-213.
10. Kondo S. The roles of cytokines in photoaging. J Dermatol Sci 2000, 23(Suppl. 1):S30-S36.
11. Park C.H., Lee M.J., Ahn J., Kim S., Kim H.H., Kim K.H., et al. Heat shock-induced matrix metalloproteinase (MMP)-1 and MMP-3 are mediated through ERK and JNK activation and via an autocrine interleukin-6 loop. J Invest Dermatol 2004, 123:1012-1019.
12. Moon S.E., Bhagavathula N., Varani J. Keratinocyte stimulation of matrix metalloproteinase-1 production and proliferation in fibroblasts: regulation through mitogen-activated protein kinase signalling events. Br J Cancer 2002, 87:457-464.
13. Mimura Y., Ihn H., Jinnin M., Asano Y., Yamane K., Tamaki K. Epidermal growth factor affects the synthesis and degradation of type I collagen in cultured human dermal fibroblasts. Matrix Biol 2006, 25:202-212.
14. Li W.H., Lee Y.M., Kim J.Y., Kang S., Kim S., Kim K.H., et al. Transient receptor potential vanilloid-1 mediates heat-shock-induced matrix metalloproteinase-1 expression in human epidermal keratinocytes. J Invest Dermatol 2007, 127:2328-2335.
15. Davies S.P., Reddy H., Caivano M., Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000, 351:95-105.
16. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 1995, 270:16483-16486.
17. Fisher G.J., Kang S., Varani J., Bata-Csorgo Z., Wan Y., Datta S., et al. Mechanisms of photoaging and chronological skin aging. Arch Dermatol 2002, 138:1462-1470.
18. Wu G.S. The functional interactions between the p53 and MAPK signaling pathways. Cancer Biol Ther 2004, 3:156-161.
19. Jinnin M., Ihn H., Mimura Y., Asano Y., Yamane K., Tamaki K. Matrix metalloproteinase-1 up-regulation by hepatocyte growth factor in human dermal fibroblasts via ERK signaling pathway involves Ets1 and Fli1. Nucleic Acids Res 2005, 33:3540-3549.
20. Zimmermann S., Moelling K. Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 1999, 286:1741-1744.
21. Westermarck J., Li S.P., Kallunki T., Han J., Kahari V.M. p38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression. Mol Cell Biol 2001, 21:2373-2383.
22. Avdi N.J., Malcolm K.C., Nick J.A., Worthen G.S. A role for protein phosphatase-2A in p38 mitogen-activated protein kinase-mediated regulation of the c-Jun NH(2)-terminal kinase pathway in human neutrophils. J Biol Chem 2002, 277:40687-40696.
23. Guha M., Mackman N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J Biol Chem 2002, 277:32124-32132.
24. Park H.S., Kim M.S., Huh S.H., Park J., Chung J., Kang S.S., et al. Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation. J Biol Chem 2002, 277:2573-2578.
25. Airola K., Fusenig N.E. Differential stromal regulation of MMP-1 expression in benign and malignant keratinocytes. J Invest Dermatol 2001, 116:85-92.
26. Brenneisen P., Sies H., Scharffetter-Kochanek K. Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events. Ann N Y Acad Sci 2002, 973:31-43.
27. Rittie L., Fisher G.J. UV-light-induced signal cascades and skin aging. Ageing Res Rev 2002, 1:705-720.
28. Barrientos S., Stojadinovic O., Golinko M.S., Brem H., Tomic-Canic M. Growth factors and cytokines in wound healing. Wound Repair Regen 2008, 16:585-601.
29. Chen P., Gupta K., Wells A. Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis. J Cell Biol 1994, 124:547-555.
30. Chen P., Xie H., Sekar M.C., Gupta K., Wells A. Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement. J Cell Biol 1994, 127:847-857.
31. Chen P., Xie H., Wells A. Mitogenic signaling from the EGF receptor is attenuated by a phospholipase C-gamma/protein kinase C feedback mechanism. Mol Biol Cell 1996, 7:871-881.
32. Mimura Y., Ihn H., Jinnin M., Asano Y., Yamane K., Tamaki K. Epidermal growth factor induces fibronectin expression in human dermal fibroblasts via protein kinase C delta signaling pathway. J Invest Dermatol 2004, 122:1390-1398.
33. Cao C., Sun Y., Healey S., Bi Z., Hu G., Wan S., et al. EGFR-mediated expression of aquaporin-3 is involved in human skin fibroblast migration. Biochem J 2006, 400:225-234.
34. Wells A., Gupta K., Chang P., Swindle S., Glading A., Shiraha H. Epidermal growth factor receptor-mediated motility in fibroblasts. Microsc Res Tech 1998, 43:395-411.
35. Ohgoda O., Sakai A., Koga H., Kanai K., Miyazaki T., Niwano Y. Fibroblast-migration in a wound model of ascorbic acid-supplemented three-dimensional culture system: the effects of cytokines and malotilate, a new wound healing stimulant, on cell-migration. J Dermatol Sci 1998, 17:123-131.
36. Ravanti L., Kahari V.M. Matrix metalloproteinases in wound repair. Int J Mol Med 2000, 6:391-407. [review].
37. Vu T.H., Werb Z. Matrix metalloproteinases: effectors of development and normal physiology. Genes Dev 2000, 14:2123-2133.
38. Guan K.L., Figueroa C., Brtva T.R., Zhu T., Taylor J., Barber T.D., et al. Negative regulation of the serine/threonine kinase B-Raf by Akt. J Biol Chem 2000, 275:27354-27359.
39. Rommel C., Clarke B.A., Zimmermann S., Nunez L., Rossman R., Reid K., et al. Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. Science 1999, 286:1738-1741.
40. Endo H., Utani A., Shinkai H. Activation of p38 MAPK suppresses matrix metalloproteinase-1 gene expression induced by platelet-derived growth factor. Arch Dermatol Res 2003, 294:552-558.
41. Lee Y., Kim H., Kim S., Kim K.H., Chung J.H. Activation of toll-like receptors 2, 3 or 5 induces matrix metalloproteinase-1 and -9 expression with the involvement of MAPKs and NF-kappaB in human epidermal keratinocytes. Exp Dermatol 2010, 19:e44-e49.