Detection and chemical profiling of medicine counterfeits by Raman spectroscopy and chemometrics

Analytica Chimica Acta

Volumn 705, Issue 1-2, 2011, Pages 334-341

  Dégardin, Klara ^a,b   Roggo, Yves ^a   Been, Frederic ^b   Margot, Pierre ^b  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Chemical identification; Chemometrics; Counterfeit medicines; Forensic intelligence; Profiling; Raman spectroscopy

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; ANALYTICAL TOOL; CHEMICAL IDENTIFICATION; CHEMICAL PROFILING; CHEMOMETRICS; FORENSIC INTELLIGENCE; INTEGRAL PART; NONLINEAR CLASSIFICATION; PHARMACEUTICAL TABLETS; PROFILING; SOLID FORMS;

CHEMICAL DETECTION; PRINCIPAL COMPONENT ANALYSIS; RAMAN SCATTERING; RAMAN SPECTROSCOPY; SPECTRUM ANALYSIS; SUPPORT VECTOR MACHINES;

CRIME;

COUNTERFEIT DRUG; SIBUTRAMINE; STARCH; TALC;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL PROFILING; CHEMOMETRIC ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CRIME; DATA BASE; DRUG CAPSULE; FORENSIC SCIENCE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SUPPORT VECTOR MACHINE; TABLET; VALIDATION STUDY;

CALIBRATION; CAPSULES; COUNTERFEIT DRUGS; PRINCIPAL COMPONENT ANALYSIS; SPECTRUM ANALYSIS, RAMAN; SUPPORT VECTOR MACHINES; TABLETS;

EID: 80053383615     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2011.07.043     Document Type: Article

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