Brain-derived neurotrophic factor inhibition at the punctured intervertebral disc downregulates the production of calcitonin gene-related peptide in dorsal root ganglia in rats

Spine

Volumn 36, Issue 21, 2011, Pages 1737-1743

  Orita, Sumihisa ^a,b   Eguchi, Yawara ^b   Kamoda, Hiroto ^b   Arai, Gen ^b   Ishikawa, Tetsuhiro ^b   Miyagi, Masayuki ^b   Inoue, Gen ^b   Suzuki, Miyako ^b   Toyone, Tomoaki ^b   Aoki, Yasuchika ^b   Takahashi, Kazuhisa ^b   Ohtori, Seiji ^b  

^a CHIBA ROSAI HOSPITAL   (Japan)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

brain derived neurotrophic factor; calcitonin generelated peptide; discogenic low back pain; dorsal root ganglion; lumbar intervertebral disc; sensory innervation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCITONIN GENE RELATED PEPTIDE; FLUOROGOLD;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATIONAL STUDY; DISCOGENIC PAIN; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTERVERTEBRAL DISK DEGENERATION; LUMBAR DISK; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUNCTURE; RAT; SENSORY NERVE; SPINAL GANGLION; SPINE INJURY;

ANIMALS; ANTIBODIES; BACK PAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CALCITONIN GENE-RELATED PEPTIDE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; LUMBAR VERTEBRAE; NEUROANATOMICAL TRACT-TRACING TECHNIQUES; PUNCTURES; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 80053348144     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e31821d7b9f     Document Type: Article

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