Optimizing protocols for risk prediction in asymptomatic carotid stenosis using embolic signal detection: The asymptomatic carotid emboli study

Stroke

Volumn 42, Issue 10, 2011, Pages 2819-2824

  King, Alice ^a   Shipley, Martin ^b   Markus, Hugh ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

arotid stenosis; embolism; outcome; risk factors; transcranial Doppler

Indexed keywords

ACCURACY; AGED; ARTICLE; ASYMPTOMATIC DISEASE; CARDIOVASCULAR RISK; CAROTID ARTERY OBSTRUCTION; CLINICAL PROTOCOL; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DOPPLER ECHOGRAPHY; EMBOLIC SIGNAL; EMBOLISM; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SIGNAL DETECTION; STROKE;

AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; CAROTID STENOSIS; EMBOLISM; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SENSITIVITY AND SPECIFICITY; STROKE; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL;

EID: 80053339192     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.622514     Document Type: Article

References (11)

1. Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. JAMA. 1995;273:1421-1428.
2. Halliday A, Mansfield A, Marro J, Peto C, Peto R, Potter J, et al. Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. Lancet. 2004;363:1491-1502.
3. Abbott AL. Medical (nonsurgical) intervention alone is now best for prevention of stroke associated with asymptomatic severe carotid stenosis: Results of a systematic review and analysis. Stroke. 2009;40: e573-e583.
4. Marquardt L, Geraghty OC, Mehta Z, Rothwell PM. Low risk of ipsilateral stroke in patients with asymptomatic carotid stenosis on best medical treatment: a prospective, population-based study. Stroke. 2010; 41:e11-e17.
5. Spence JD, Coates V, Li H, Tamayo A, Muñoz C, Hackam DG, et al. Effects of intensive medical therapy on microemboli and cardiovascular risk in asymptomatic carotid stenosis. Arch Neurol. 2010;67:180-186.
6. Abbott AL, Chambers BR, Stork JL, Levi CR, Bladin CF, Donnan GA. Embolic signals and prediction of ipsilateral stroke or transient ischemic attack in asymptomatic carotid stenosis: A multicenter prospective cohort study. Stroke. 2005;36:1128-1133. (Pubitemid 40798727)
7. Markus HS, King A, Shipley M, Topakian R, Cullinane M, Reihill S, et al. Asymptomatic embolisation for prediction of stroke in the Asymptomatic Carotid Emboli Study (ACES): a prospective observational study. Lancet Neurol. 2010;9:663-671.
8. Spence JD, Tamayo A, Lownie SP, Ng WP, Ferguson GG. Absence of microemboli on transcranial Doppler identifies low-risk patients with asymptomatic carotid stenosis. Stroke. 2005;36:2373-2378. (Pubitemid 41566961)
9. ACES Investigators. The Asymptomatic Carotid Emboli Study: study design and baseline results. Int J Stroke. 2009;4:398-405.
10. Hanley JA, McNeil BJ. A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology. 1983;148:839-843. (Pubitemid 13033817)
11. Mackinnon AD, Aaslid R, Markus HS. Ambulatory transcranial Doppler cerebral embolic signal detection in symptomatic and asymptomatic carotid stenosis. Stroke. 2005;36:1726-1730. (Pubitemid 41098770)