Impaired striatal akt signaling disrupts dopamine homeostasis and increases feeding

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Speed, Nicole ^b   Saunders, Christine ^b   Davis, Adeola R ^a   Owens, W Anthony ^c   Matthies, Heinrich J G ^a   Saadat, Sanaz ^g   Kennedy, Jack P ^b   Vaughan, Roxanne A ^d   Neve, Rachael L ^f   Lindsley, Craig W ^b   Russo, Scott J ^e   Daws, Lynette C ^c   Niswender, Kevin D ^b,g   Galli, Aurelio ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c University of Texas Health Science Center   (United States)

^d UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g Tennessee Valley Healthcare System   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; DOPAMINE; DOPAMINE TRANSPORTER; INSULIN; PROTEIN KINASE B; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CELL SURFACE; CONTROLLED STUDY; DOPAMINE RELEASE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEEDING BEHAVIOR; FOOD INTAKE; HYPERPHAGIA; LIPID DIET; LOCOMOTION; MALE; MOLECULAR MODEL; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; STRIATE CORTEX; WEIGHT GAIN; ANIMAL; BIOTINYLATION; BRAIN; CELL MEMBRANE; CORPUS STRIATUM; HOMEOSTASIS; METABOLISM; SPRAGUE DAWLEY RAT; SUBSTANTIA NIGRA; TRANSPORT AT THE CELLULAR LEVEL;

RATTUS;

ANIMALS; BIOLOGICAL TRANSPORT; BIOTINYLATION; BRAIN; CELL MEMBRANE; CORPUS STRIATUM; DIET, HIGH-FAT; DOPAMINE; HOMEOSTASIS; INSULIN; LOCOMOTION; MALE; OBESITY; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA;

EID: 80053319017     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025169     Document Type: Article

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