Effect of hydroxypropyl-β-cyclodextrin on the ocular bioavailability of dexamethasone from a pH-induced mucoadhesive hydrogel

Current Eye Research

Volumn 36, Issue 10, 2011, Pages 918-929

  Kesavan, Karthikeyan ^a   Kant, Shri ^b   Singh, Paras Nath ^a   Pandit, Jayanta Kumar ^a  

^a BANARAS HINDU UNIVERSITY   (India)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

Carbopol; Dexamethasone; HP CD; Mucoadhesive; pH induced hydrogel; Sodium CMC; Uveitis

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; CARBOMER; CARBOPOL 980 NF; CARBOXYMETHYLCELLULOSE; DEXAMETHASONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; AQUEOUS SOLUTION; ARTICLE; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG RETENTION; DRUG SOLUBILITY; DRUG STABILITY; EXPERIMENTAL RABBIT; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROMETRY; LACRIMAL FLUID; NONHUMAN; PH; PH SENSITIVE MUCOADHESIVE HYDROGEL SYSTEM; PHASE TRANSITION; PRIORITY JOURNAL; SIMULATION; SOLID; UVEITIS; X RAY DIFFRACTION;

ACRYLIC RESINS; ANIMALS; ANTI-INFLAMMATORY AGENTS; AQUEOUS HUMOR; BETA-CYCLODEXTRINS; BIOLOGICAL AVAILABILITY; CARBOXYMETHYLCELLULOSE SODIUM; CELL COUNT; DEXAMETHASONE; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; EXCIPIENTS; HYDROGELS; HYDROGEN-ION CONCENTRATION; OPHTHALMIC SOLUTIONS; RABBITS; SPECTROPHOTOMETRY, INFRARED; UVEITIS, ANTERIOR; VISCOSITY; X-RAY DIFFRACTION;

EID: 80053303193     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2011.593728     Document Type: Article

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