Human atherosclerotic plaque lipid extract promotes expression of proinflammatory factors in human monocytes and macrophage-like cells

Atherosclerosis

Volumn 218, Issue 2, 2011, Pages 339-343

  Yehuda, Hila ^a   Szuchman Sapir, Andrea ^a,b   Khatib, Soliman ^a,b   Musa, Ramadan ^a   Tamir, Snait ^a,b  

^a MIGAL GALILEE TECHNOLOGY CENTER   (Israel)

^b TEL HAI COLLEGE   (Israel)

Author keywords

Atherosclerosis; Cytokines; Inflammation; Macrophage; Monocyte; Plaque

Indexed keywords

CHOLESTEROL; CYCLOOXYGENASE 2; CYTOKINE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; OXYSTEROL; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ATHEROSCLEROTIC PLAQUE; CYTOKINE RELEASE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

CAROTID ARTERIES; CELL LINE; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPIDS; MACROPHAGES; MONOCYTES; PLAQUE, ATHEROSCLEROTIC; RNA, MESSENGER; STEROLS; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80053291420     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.07.120     Document Type: Article

References (20)

1. Oikawa M., Ota H., Takaya N., et al. Carotid magnetic resonance imaging. A window to study atherosclerosis and identify high-risk plaques. Circ J 2009, 73:1765-1773.
2. Hansson G.K., Inflammation atherosclerosis, and coronary artery disease. N Engl J Med 2005, 352:1685-1695.
3. Saha P., Modarai B., Humphries J., et al. The monocyte/macrophage as a therapeutic target in atherosclerosis. Curr Opin Pharmacol 2009, 9:109-118.
4. Cipollone F., Cicolini G., Bucci M. Cyclooxygenase and prostaglandin synthases in atherosclerosis: recent insights and future perspectives. Pharmacol Ther 2008, 118:161-180.
5. Aviram M., Hardak E., Vaya J., et al. Human serum paraoxonases (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions: PON1 esterase and peroxidase-like activities. Circulation 2000, 101:2510-2517.
6. Tavori H., Aviram M., Khatib S., et al. Human carotid atherosclerotic plaque increases oxidative state of macrophages and low-density lipoproteins, whereas paraoxonase 1 (PON1) decreases such atherogenic effects. Free Radic Biol Med 2009, 46:607-615.
7. Libby P., Okamoto Y., Rocha V.Z., et al. Inflammation in atherosclerosis: transition from theory to practice. Circ J 2010, 74:213-220.
8. Galkina E., Ley K. Vascular adhesion molecules in atherosclerosis. Arterioscler Thromb Vasc Biol 2007, 27:2292-2301.
9. Libby P., Ridker P.M., Hansson G.K. Inflammation in atherosclerosis: from pathophysiology to practice. J Am Coll Cardiol 2009, 54:2129-2138.
10. Kleemann R., Zadelaar S., Kooistra T. Cytokines atherosclerosis: a comprehensive review of studies in mice. Cardiovasc Res 2008, 79:360-376.
11. Schuett H., Luchtefeld M., Grothusen C., et al. How much is too much? Interleukin-6 and its signalling in atherosclerosis. Thromb Haemost 2009, 102:215-222.
12. Tavori H., Aviram M., Khatib S., et al. Human carotid lesion linoleic acid hydroperoxide inhibits paraoxonase 1 (PON1) activity via reaction with PON1 free sulfhydryl cysteine 284. Free Radic Biol Med 2011, 50:148-156.
13. Park E.K., Jung H.S., Yang H.I., et al. Optimized THP-1 differentiation is required for the detection of responses to weak stimuli. Inflamm Res 2007, 56:45-50.
14. Tanigawa T., Watanabe T., Higuchi K., et al. Lansoprazole, a proton pump inhibitor, suppresses production of tumor necrosis factor-alpha and interleukin-1beta induced by lipopolysaccharide and helicobacter pylori bacterial components in human monocytic cells via inhibition of activation of nuclear factor-kappaB and extracellular signal-regulated kinase. J Clin Biochem Nutr 2009, 45:86-92.
15. Schottelius A.J., Moldawer L.L., Dinarello C.A., et al. Biology of tumor necrosis factor-alpha- implications for psoriasis. Exp Dermatol 2004, 13:193-222.
16. Prunet C., Montange T., Vejux A., et al. Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients. Cytometry A 2006, 69:359-373.
17. Bjorkhem I., Diczfalusy U. Oxysterols: friends, foes, or just fellow passengers?. Arterioscler Thromb Vasc Biol 2002, 22:734-742.
18. Poli G., Sottero B., Gargiulo S., et al. Cholesterol oxidation products in the vascular remodeling due to atherosclerosis. Mol Aspects Med 2009, 30:180-189.
19. Calder P.C., Jensen G.L., Koletzko B.V., et al. Lipid emulsions in parenteral nutrition of intensive care patients: current thinking and future directions. Intensive Care Med 2010, 36:735-749.
20. Tavori H., Aviram M., Khatib S., et al. Paraoxonase 1 protects macrophages from atherogenicity of a specific triglyceride isolated from human carotid lesion. Free Radic Biol Med 2011, 51:234-242.