RITA-Registry of Industrial Toxicology Animal data: The application of historical control data for Leydig cell tumors in rats

Experimental and Toxicologic Pathology

Volumn 63, Issue 7-8, 2011, Pages 645-656

  Nolte, Thomas ^a   Rittinghausen, Susanne ^b   Kellner, Rupert ^b   Karbe, Eberhard ^c   Kittel, Birgit ^d   Rinke, Matthias ^e   Deschl, Ulrich ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^c Consultancy ^*  (Germany)

^d NOVARTIS PHARMA AG   (Switzerland)

^e BAYER PHARMA AG   (Germany)

Author keywords

Carcinogenicity; Carcinogenicity testing; Historical control data; Interstitial cell adenoma; Interstitial cell carcinoma; Interstitial cell tumor; Leydig cell adenoma; Leydig cell carcinoma; Leydig cell tumor; Oncogenicity; Rat; Registry of Industrial Toxicology Animal (RITA) data; Rodent; Testes; Testis

Indexed keywords

ADENOMA; AGE; ARTICLE; AUTOPSY; BODY WEIGHT; CANCER INCIDENCE; CARCINOGEN TESTING; CHEMICAL CARCINOGENESIS; DATA BASE; FISCHER 344 RAT; LEYDIG CELL ADENOMA; LEYDIG CELL CARCINOMA; LEYDIG CELL TUMOR; NONHUMAN; RAT; REGISTER; SPRAGUE DAWLEY RAT; STRAIN DIFFERENCE; WISTAR RAT;

ADENOCARCINOMA; ADENOMA; ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; DATA COLLECTION; DATABASES, FACTUAL; LEYDIG CELL TUMOR; MALE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; REFERENCE VALUES; REGISTRIES;

ANIMALIA; RATTUS; RATTUS NORVEGICUS; RODENTIA;

EID: 80053233182     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2010.05.006     Document Type: Article

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