Ruthenium(II) phosphine/diimine/picolinate complexes: Inorganic compounds as agents against tuberculosis

European Journal of Medicinal Chemistry

Volumn 46, Issue 10, 2011, Pages 5099-5107

  Pavan, Fernando R ^a   Poelhsitz, Gustavo V ^b   Barbosa, Marilia I F ^c   Leite, Sergio R A ^a   Batista, Alzir A ^c   Ellena, Javier ^d   Sato, Leticia S ^a   Franzblau, Scott G ^e   Moreno, Virtudes ^f   Gambino, Dinorah ^g   Leite, Clarice Q F ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^f UNIVERSITY OF BARCELONA   (Spain)

^g UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Drug resistance; Mycobacterium tuberculosis; Phosphine diimine picolinate; Ruthenium

Indexed keywords

1,10 PHENANTHROLINE; 2,2' BIPYRIDINE; 4,4' DICHLORO 2,2' BIPYRIDINE; 4,4' DIMETHYL 2,2' BIPYREDINE; DNA; FUNCTIONAL GROUP; N (2 ADAMANTYL) N' GERANYLETHYLENEDIAMINE; PHOSPHINE; PICOLINIC ACID; PYRIDINE DERIVATIVE; RIFAMPICIN; RUTHENIUM COMPLEX; SCAR 01; SCAR 02; SCAR 03; SCAR 04; SCAR 05; SCAR 06; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; CELL ACTIVITY; CYTOTOXICITY; DRUG ACTIVITY; DRUG DNA BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; MACROPHAGE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; VISCOSITY;

ANIMALS; ANTITUBERCULAR AGENTS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; HUMANS; IMINES; MICE; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; ORGANOMETALLIC COMPOUNDS; PHOSPHINES; PICOLINIC ACIDS; RUTHENIUM; TUBERCULOSIS;

EID: 80053206679     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.08.023     Document Type: Article

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