Design, synthesis and evaluation of PEGylated lipoic acid derivatives with functionality as potent anti-melanogenic agents

European Journal of Medicinal Chemistry

Volumn 46, Issue 10, 2011, Pages 5184-5188

  Lu, Chichong ^a   Kim, Bo Mi ^a   Chai, Kyu Yun ^a  

^a Wonkwang University   (South Korea)

Author keywords

Functionality; Lipoic acid; Melanin inhibitors; Polyethylene glycol

Indexed keywords

DEPIGMENTING AGENT; INTERSTITIAL COLLAGENASE; MACROGOL; MELANIN; MOLECULAR SCAFFOLD; PEGYLATED LIPOIC ACID ESTER DERIVATIVE; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANTIMELANOGENIC ACTIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG DISTRIBUTION; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; MELANOGENESIS; MELANOMA CELL; MOUSE; NONHUMAN; PHARMACOPHORE; PROTEIN EXPRESSION; SOLUBILITY; ULTRAVIOLET RADIATION;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DESIGN; GENE EXPRESSION REGULATION; HUMANS; MATRIX METALLOPROTEINASE 1; MELANINS; MICE; POLYETHYLENE GLYCOLS; THIOCTIC ACID; ULTRAVIOLET RAYS;

EID: 80053187016     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.07.056     Document Type: Article

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