Effective encapsulation of a new cationic gadolinium chelate into apoferritin and its evaluation as an MRI contrast agent

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 7, Issue 5, 2011, Pages 638-646

  Makino, Akira ^a   Harada, Hiroshi ^a   Okada, Tomohisa ^a   Kimura, Hiroyuki ^a   Amano, Hiroo ^a   Saji, Hideo ^a   Hiraoka, Masahiro ^a   Kimura, Shunsaku ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Apoferritin; Drug delivery; Gadolinium complex; Magnetic resonance imaging; Molecular imaging

Indexed keywords

APOFERRITIN; CONTRAST AGENT; ENCAPSULATION METHODS; ENHANCED PERMEATION AND RETENTIONS; GADOLINIUM COMPLEXES; GADOLINIUM IONS; GD-DOTA; HIGH-T; IN-VIVO; ITS EVALUATION; MAGNETIC RESONANCE IMAGING CONTRAST AGENTS; MOLECULAR IMAGING; MRI CONTRAST AGENTS; RELAXIVITY; SENSITIVE METHOD; SIDE EFFECT; SINGLE-DOSE; TOXICITY TEST; TUMOR DETECTION; WATER MOLECULE;

CHELATION; DRUG DELIVERY; MAGNETIC RESONANCE IMAGING; PROTONS; RESONANCE; TOXICITY; TUMORS;

GADOLINIUM;

APOFERRITIN; DEXTRAN; GADOLINIUM CHELATE; GADOTERIC ACID; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG FORMULATION; ENCAPSULATION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; TOXICITY TESTING; TUMOR DIAGNOSIS;

ANIMALS; APOFERRITINS; CATIONS; CHELATING AGENTS; CONTRAST MEDIA; COORDINATION COMPLEXES; HETEROCYCLIC COMPOUNDS; MAGNETIC RESONANCE IMAGING; MICE; NANOCAPSULES; NEOPLASMS; ORGANOMETALLIC COMPOUNDS;

MUS;

EID: 80053180576     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2011.01.015     Document Type: Article

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