-
1
-
-
33646799069
-
Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data
-
10.1016/S0140-6736(06)68770-9, 16731270
-
Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 2006, 367:1747-1757. 10.1016/S0140-6736(06)68770-9, 16731270.
-
(2006)
Lancet
, vol.367
, pp. 1747-1757
-
-
Lopez, A.D.1
Mathers, C.D.2
Ezzati, M.3
Jamison, D.T.4
Murray, C.J.5
-
2
-
-
0038363984
-
Glycoprotein Ib-IX-V
-
10.1016/S1357-2725(02)00280-7, 12757754
-
Andrews RK, Gardiner EE, Shen Y, Whisstock JC, Berndt MC. Glycoprotein Ib-IX-V. Int J Biochem Cell Biol 2003, 35:1170-1174. 10.1016/S1357-2725(02)00280-7, 12757754.
-
(2003)
Int J Biochem Cell Biol
, vol.35
, pp. 1170-1174
-
-
Andrews, R.K.1
Gardiner, E.E.2
Shen, Y.3
Whisstock, J.C.4
Berndt, M.C.5
-
3
-
-
41149168746
-
Inherited traits affecting platelet function
-
10.1016/j.blre.2007.11.002, 18180086
-
Salles II, Feys HB, Iserbyt BF, De Meyer SF, Vanhoorelbeke K, Deckmyn H. Inherited traits affecting platelet function. Blood Rev 2008, 22:155-172. 10.1016/j.blre.2007.11.002, 18180086.
-
(2008)
Blood Rev
, vol.22
, pp. 155-172
-
-
Salles, I.I.1
Feys, H.B.2
Iserbyt, B.F.3
De Meyer, S.F.4
Vanhoorelbeke, K.5
Deckmyn, H.6
-
4
-
-
67149132162
-
Von Willebrand factor to the rescue
-
10.1182/blood-2008-10-165621, 19318682
-
De Meyer SF, Deckmyn H, Vanhoorelbeke K. von Willebrand factor to the rescue. Blood 2009, 113:5049-5057. 10.1182/blood-2008-10-165621, 19318682.
-
(2009)
Blood
, vol.113
, pp. 5049-5057
-
-
De Meyer, S.F.1
Deckmyn, H.2
Vanhoorelbeke, K.3
-
5
-
-
33750941414
-
The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis
-
10.1073/pnas.0608207103, 1636551, 17075060
-
Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD. The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis. Proc Natl Acad Sci USA 2006, 103:16900-16905. 10.1073/pnas.0608207103, 1636551, 17075060.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16900-16905
-
-
Bergmeier, W.1
Piffath, C.L.2
Goerge, T.3
Cifuni, S.M.4
Ruggeri, Z.M.5
Ware, J.6
Wagner, D.D.7
-
6
-
-
0037105457
-
Amelioration of the macrothrombocytopenia associated with the murine Bernard-Soulier syndrome
-
10.1182/blood-2002-03-0997, 12200373
-
Kanaji T, Russell S, Ware J. Amelioration of the macrothrombocytopenia associated with the murine Bernard-Soulier syndrome. Blood 2002, 100:2102-2107. 10.1182/blood-2002-03-0997, 12200373.
-
(2002)
Blood
, vol.100
, pp. 2102-2107
-
-
Kanaji, T.1
Russell, S.2
Ware, J.3
-
7
-
-
0030794929
-
Overexpression of CuZn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice
-
10.1161/01.STR.28.9.1797, 9303028
-
Murakami K, Kondo T, Epstein CJ, Chan PH. Overexpression of CuZn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice. Stroke 1997, 28:1797-1804. 10.1161/01.STR.28.9.1797, 9303028.
-
(1997)
Stroke
, vol.28
, pp. 1797-1804
-
-
Murakami, K.1
Kondo, T.2
Epstein, C.J.3
Chan, P.H.4
-
8
-
-
65349125946
-
Deficiency of von Willebrand factor protects mice from ischemic stroke
-
10.1182/blood-2008-09-180695, 19182208
-
Kleinschnitz C, De Meyer SF, Schwarz T, Austinat M, Vanhoorelbeke K, Nieswandt B, Deckmyn H, Stoll G. Deficiency of von Willebrand factor protects mice from ischemic stroke. Blood 2009, 113:3600-3603. 10.1182/blood-2008-09-180695, 19182208.
-
(2009)
Blood
, vol.113
, pp. 3600-3603
-
-
Kleinschnitz, C.1
De Meyer, S.F.2
Schwarz, T.3
Austinat, M.4
Vanhoorelbeke, K.5
Nieswandt, B.6
Deckmyn, H.7
Stoll, G.8
-
9
-
-
77957714714
-
Binding of von Willebrand Factor to Collagen and Glycoprotein Ibalpha, But Not to Glycoprotein IIb/IIIa, Contributes to Ischemic Stroke in Mice
-
10.1161/ATVBAHA.110.208918, 20616311
-
De Meyer SF, Schwarz T, Deckmyn H, Denis CV, Nieswandt B, Stoll G, Vanhoorelbeke K, Kleinschnitz C. Binding of von Willebrand Factor to Collagen and Glycoprotein Ibalpha, But Not to Glycoprotein IIb/IIIa, Contributes to Ischemic Stroke in Mice. Arterioscler Thromb Vasc Biol 2010, 30:1949-1951. 10.1161/ATVBAHA.110.208918, 20616311.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1949-1951
-
-
De Meyer, S.F.1
Schwarz, T.2
Deckmyn, H.3
Denis, C.V.4
Nieswandt, B.5
Stoll, G.6
Vanhoorelbeke, K.7
Kleinschnitz, C.8
-
10
-
-
0031439697
-
Monofilament intraluminal middle cerebral artery occlusion in the mouse
-
Clark WM, Lessov NS, Dixon MP, Eckenstein F. Monofilament intraluminal middle cerebral artery occlusion in the mouse. Neurol Res 1997, 19:641-648.
-
(1997)
Neurol Res
, vol.19
, pp. 641-648
-
-
Clark, W.M.1
Lessov, N.S.2
Dixon, M.P.3
Eckenstein, F.4
-
11
-
-
0022483434
-
Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination
-
10.1161/01.STR.17.3.472, 3715945
-
Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 1986, 17:472-476. 10.1161/01.STR.17.3.472, 3715945.
-
(1986)
Stroke
, vol.17
, pp. 472-476
-
-
Bederson, J.B.1
Pitts, L.H.2
Tsuji, M.3
Nishimura, M.C.4
Davis, R.L.5
Bartkowski, H.6
-
12
-
-
55749101354
-
Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment
-
10.1182/blood-2008-04-144758, 18676880
-
Stoll G, Kleinschnitz C, Nieswandt B. Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment. Blood 2008, 112:3555-3562. 10.1182/blood-2008-04-144758, 18676880.
-
(2008)
Blood
, vol.112
, pp. 3555-3562
-
-
Stoll, G.1
Kleinschnitz, C.2
Nieswandt, B.3
-
13
-
-
77956988100
-
The role of glycoprotein Ibalpha and von Willebrand factor interaction in stroke development
-
Stoll G, Kleinschnitz C, Nieswandt B. The role of glycoprotein Ibalpha and von Willebrand factor interaction in stroke development. Hämostaseologie 2010, 30:136-138.
-
(2010)
Hämostaseologie
, vol.30
, pp. 136-138
-
-
Stoll, G.1
Kleinschnitz, C.2
Nieswandt, B.3
-
14
-
-
34247643257
-
Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding
-
10.1161/CIRCULATIONAHA.107.691279, 17438148
-
Kleinschnitz C, Pozgajova M, Pham M, Bendszus M, Nieswandt B, Stoll G. Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding. Circulation 2007, 115:2323-2330. 10.1161/CIRCULATIONAHA.107.691279, 17438148.
-
(2007)
Circulation
, vol.115
, pp. 2323-2330
-
-
Kleinschnitz, C.1
Pozgajova, M.2
Pham, M.3
Bendszus, M.4
Nieswandt, B.5
Stoll, G.6
-
15
-
-
70350483024
-
Von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke
-
10.1182/blood-2009-03-213264, 2759655, 19687510
-
Zhao B-Q, Chauhan AK, Canault M, Patten IS, Yang JJ, Dockal M, Scheiflinger F, Wagner DD. von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke. Blood 2009, 114:3329-3334. 10.1182/blood-2009-03-213264, 2759655, 19687510.
-
(2009)
Blood
, vol.114
, pp. 3329-3334
-
-
Zhao, B.-Q.1
Chauhan, A.K.2
Canault, M.3
Patten, I.S.4
Yang, J.J.5
Dockal, M.6
Scheiflinger, F.7
Wagner, D.D.8
-
16
-
-
0035385125
-
Platelet glycoprotein Ibalpha Kozak polymorphism is associated with an increased risk of ischemic stroke
-
10.1182/blood.V98.1.36, 11418460
-
Baker RI, Eikelboom J, Lofthouse E, Staples N, Afshar-Kharghan V, López JA, Shen Y, Berndt MC, Hankey G. Platelet glycoprotein Ibalpha Kozak polymorphism is associated with an increased risk of ischemic stroke. Blood 2001, 98:36-40. 10.1182/blood.V98.1.36, 11418460.
-
(2001)
Blood
, vol.98
, pp. 36-40
-
-
Baker, R.I.1
Eikelboom, J.2
Lofthouse, E.3
Staples, N.4
Afshar-Kharghan, V.5
López, J.A.6
Shen, Y.7
Berndt, M.C.8
Hankey, G.9
-
17
-
-
0033937685
-
Genetic variants of platelet glycoprotein receptors and risk of stroke in young women
-
10.1161/01.STR.31.7.1628, 10884464
-
Reiner AP, Kumar PN, Schwartz SM, Longstreth WT, Pearce RM, Rosendaal FR, Psaty BM, Siscovick DS. Genetic variants of platelet glycoprotein receptors and risk of stroke in young women. Stroke 2000, 31:1628-1633. 10.1161/01.STR.31.7.1628, 10884464.
-
(2000)
Stroke
, vol.31
, pp. 1628-1633
-
-
Reiner, A.P.1
Kumar, P.N.2
Schwartz, S.M.3
Longstreth, W.T.4
Pearce, R.M.5
Rosendaal, F.R.6
Psaty, B.M.7
Siscovick, D.S.8
-
18
-
-
33750949797
-
High von Willebrand factor levels increase the risk of first ischemic stroke: influence of ADAMTS13, inflammation, and genetic variability
-
10.1161/01.STR.0000244767.39962.f7, 16990571
-
Bongers TN, de Maat MPM, van Goor M-LPJ, Bhagwanbali V, van Vliet HHDM, Gómez García EB, Dippel DWJ, Leebeek FWG. High von Willebrand factor levels increase the risk of first ischemic stroke: influence of ADAMTS13, inflammation, and genetic variability. Stroke 2006, 37:2672-2677. 10.1161/01.STR.0000244767.39962.f7, 16990571.
-
(2006)
Stroke
, vol.37
, pp. 2672-2677
-
-
Bongers, T.N.1
de Maat, M.P.M.2
van Goor, M.-L.P.J.3
Bhagwanbali, V.4
van Vliet, H.H.D.M.5
Gómez García, E.B.6
Dippel, D.W.J.7
Leebeek, F.W.G.8
-
19
-
-
77958021914
-
High von Willebrand Factor Levels Increase the Risk of Stroke. The Rotterdam Study
-
10.1161/STROKEAHA.110.586289, 20798373
-
Wieberdink RG, van Schie MC, Koudstaal PJ, Hofman A, Witteman JCM, de Maat MPM, Leebeek FWG, Breteler MMB. High von Willebrand Factor Levels Increase the Risk of Stroke. The Rotterdam Study. Stroke 2010, 41:2151-2156. 10.1161/STROKEAHA.110.586289, 20798373.
-
(2010)
Stroke
, vol.41
, pp. 2151-2156
-
-
Wieberdink, R.G.1
van Schie, M.C.2
Koudstaal, P.J.3
Hofman, A.4
Witteman, J.C.M.5
de Maat, M.P.M.6
Leebeek, F.W.G.7
Breteler, M.M.B.8
-
20
-
-
51649122550
-
Restoration of plasma von Willebrand factor deficiency is sufficient to correct thrombus formation after gene therapy for severe von Willebrand disease
-
10.1161/ATVBAHA.108.168369, 18556568
-
De Meyer SF, Vandeputte N, Pareyn I, Petrus I, Lenting PJ, Chuah MKL, VandenDriessche T, Deckmyn H, Vanhoorelbeke K. Restoration of plasma von Willebrand factor deficiency is sufficient to correct thrombus formation after gene therapy for severe von Willebrand disease. Arterioscler Thromb Vasc Biol 2008, 28:1621-1626. 10.1161/ATVBAHA.108.168369, 18556568.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1621-1626
-
-
De Meyer, S.F.1
Vandeputte, N.2
Pareyn, I.3
Petrus, I.4
Lenting, P.J.5
Chuah, M.K.L.6
VandenDriessche, T.7
Deckmyn, H.8
Vanhoorelbeke, K.9
-
21
-
-
0032483024
-
A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis
-
10.1073/pnas.95.16.9524, 21371, 9689113
-
Denis C, Methia N, Frenette PS, Rayburn H, Ullman-Culleré M, Hynes RO, Wagner DD. A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci USA 1998, 95:9524-9529. 10.1073/pnas.95.16.9524, 21371, 9689113.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9524-9529
-
-
Denis, C.1
Methia, N.2
Frenette, P.S.3
Rayburn, H.4
Ullman-Culleré, M.5
Hynes, R.O.6
Wagner, D.D.7
-
22
-
-
65549119173
-
Von Willebrand factor: drug and drug target
-
10.2174/187152909787581327, 19275573
-
De Meyer SF, De Maeyer B, Deckmyn H, Vanhoorelbeke K. Von Willebrand factor: drug and drug target. Cardiovasc Hematol Disord Drug Targets 2009, 9:9-20. 10.2174/187152909787581327, 19275573.
-
(2009)
Cardiovasc Hematol Disord Drug Targets
, vol.9
, pp. 9-20
-
-
De Meyer, S.F.1
De Maeyer, B.2
Deckmyn, H.3
Vanhoorelbeke, K.4
-
23
-
-
33748629116
-
Development of monoclonal antibodies that inhibit platelet adhesion or aggregation as potential anti-thrombotic drugs
-
10.2174/187152906778249536, 17017902
-
De Meyer SF, Vanhoorelbeke K, Ulrichts H, Staelens S, Feys HB, Salles I, Fontayne A, Deckmyn H. Development of monoclonal antibodies that inhibit platelet adhesion or aggregation as potential anti-thrombotic drugs. Cardiovasc Hematol Disord Drug Targets 2006, 6:191-207. 10.2174/187152906778249536, 17017902.
-
(2006)
Cardiovasc Hematol Disord Drug Targets
, vol.6
, pp. 191-207
-
-
De Meyer, S.F.1
Vanhoorelbeke, K.2
Ulrichts, H.3
Staelens, S.4
Feys, H.B.5
Salles, I.6
Fontayne, A.7
Deckmyn, H.8
-
24
-
-
34548722192
-
Inhibition of platelet glycoprotein Ib and its antithrombotic potential
-
10.2174/138161207781662867, 17897012
-
Vanhoorelbeke K, Ulrichts H, Van de Walle G, Fontayne A, Deckmyn H. Inhibition of platelet glycoprotein Ib and its antithrombotic potential. Curr Pharm Des 2007, 13:2684-2697. 10.2174/138161207781662867, 17897012.
-
(2007)
Curr Pharm Des
, vol.13
, pp. 2684-2697
-
-
Vanhoorelbeke, K.1
Ulrichts, H.2
Van de Walle, G.3
Fontayne, A.4
Deckmyn, H.5
-
25
-
-
78149237097
-
Combating innate inflammation: a new paradigm for acute treatment of stroke?
-
10.1111/j.1749-6632.2010.05730.x, 20955438
-
Stoll G, Kleinschnitz C, Nieswandt B. Combating innate inflammation: a new paradigm for acute treatment of stroke?. Ann N Y Acad Sci 2010, 1207:149-154. 10.1111/j.1749-6632.2010.05730.x, 20955438.
-
(2010)
Ann N Y Acad Sci
, vol.1207
, pp. 149-154
-
-
Stoll, G.1
Kleinschnitz, C.2
Nieswandt, B.3
-
26
-
-
76449090664
-
Antithrombotic drugs for patients with ischaemic stroke and transient ischaemic attack to prevent recurrent major vascular events
-
10.1016/S1474-4422(10)70038-7, 20170841
-
Hankey GJ, Eikelboom JW. Antithrombotic drugs for patients with ischaemic stroke and transient ischaemic attack to prevent recurrent major vascular events. Lancet Neurol 2010, 9:273-284. 10.1016/S1474-4422(10)70038-7, 20170841.
-
(2010)
Lancet Neurol
, vol.9
, pp. 273-284
-
-
Hankey, G.J.1
Eikelboom, J.W.2
-
27
-
-
79961210182
-
The von Willebrand Inhibitor ARC1779 Reduces Cerebral Embolization After Carotid Endarterectomy: A Randomized Trial
-
10.1161/STROKEAHA.111.616649, 21700934
-
Markus HS, McCollum C, Imray C, Goulder MA, Gilbert J, King A. The von Willebrand Inhibitor ARC1779 Reduces Cerebral Embolization After Carotid Endarterectomy: A Randomized Trial. Stroke 2011, 42:2149-2153. 10.1161/STROKEAHA.111.616649, 21700934.
-
(2011)
Stroke
, vol.42
, pp. 2149-2153
-
-
Markus, H.S.1
McCollum, C.2
Imray, C.3
Goulder, M.A.4
Gilbert, J.5
King, A.6
|