Multiscale modeling of calcium dynamics in ventricular myocytes with realistic transverse tubules

IEEE Transactions on Biomedical Engineering

Volumn 58, Issue 10 PART 2, 2011, Pages 2947-2951

  Yu, Zeyun ^a   Yao, Guangming ^a   Hoshijima, Masahiko ^b   Michailova, Anushka ^c   Holst, Michael ^d  

^a University of Wisconsin Milwaukee   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Calcium dynamics; finite element methods (FEMs); meshless methods; numerical simulation; ventricular myocytes

Indexed keywords

BOUNDARY CONSTRAINTS; CALCIUM DYNAMICS; CALCIUM RELEASE; CARDIAC MYOCYTES; CONCENTRATION CHANGE; FINITE ELEMENT METHODS (FEMS); MESH-LESS METHODS; MULTI-SCALE MODELING; REACTION DIFFUSION; SPATIAL TEMPORALS; SUB-CELLULAR; VENTRICULAR MYOCYTES;

CALCIUM; CELL MEMBRANES; COMPUTER SIMULATION; CYTOLOGY; DIFFERENTIATION (CALCULUS); DYNAMICS; MATHEMATICAL MODELS; NONLINEAR EQUATIONS; NUMERICAL METHODS; PARTIAL DIFFERENTIAL EQUATIONS;

FINITE ELEMENT METHOD;

CALCIUM;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE; DIFFUSION; DYNAMICS; FINITE ELEMENT ANALYSIS; HEART MUSCLE CELL; HEART VENTRICLE WALL; INTERMETHOD COMPARISON; MATHEMATICAL COMPUTING; MESHLESS METHOD; MOLECULAR DYNAMICS; NONLINEAR SYSTEM; SIMULATION; TRANSVERSE TUBULAR SYSTEM;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; FINITE ELEMENT ANALYSIS; MICE; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; SARCOLEMMA;

EID: 80053149418     PISSN: 00189294     EISSN: 15582531     Source Type: Journal    
DOI: 10.1109/TBME.2011.2158316     Document Type: Article

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