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Volumn 152, Issue 10, 2011, Pages 3917-3929

Mutant forkhead L2 (FOXL2) proteins associated with Premature Ovarian Failure (POF) dimerize with wild- type FOXL2, leading to altered regulation of genes associated with granulosa cell differentiation

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; CYCLIN D2; CYTOCHROME P450; CYTOCHROME P450 C11A; FORKHEAD TRANSCRIPTION FACTOR; FORKHEAD TRANSCRIPTION FACTOR L2; HETERODIMER; HOMODIMER; STEROIDOGENIC ACUTE REGULATORY PROTEIN; UNCLASSIFIED DRUG;

EID: 80053143669     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2010-0989     Document Type: Article
Times cited : (41)

References (35)
  • 1
    • 0020508397 scopus 로고
    • The blepharophimosis, ptosis, and epicanthus inversus syndrome: Delineation of two types
    • Zlotogora J, Sagi M, Cohen T 1983 The blepharophimosis, ptosis, and epicanthus inversus syndrome: delineation of two types. Am J Hum Genet 35:1020-1027 (Pubitemid 13008598)
    • (1983) American Journal of Human Genetics , vol.35 , Issue.5 , pp. 1020-1027
    • Zlotogora, J.1    Sagi, M.2    Cohen, T.3
  • 3
    • 0023790695 scopus 로고
    • An association among blepharophimosis, resistant ovary syndrome, and true premature menopause
    • Fraser IS, Shearman RP, Smith A, Russell P 1988 An association among blepharophimosis, resistant ovary syndrome, and true premature menopause. Fertil Steril 50:747-751
    • (1988) Fertil Steril , vol.50 , pp. 747-751
    • Fraser, I.S.1    Shearman, R.P.2    Smith, A.3    Russell, P.4
  • 8
    • 3042554114 scopus 로고    scopus 로고
    • Forkhead L2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene
    • DOI 10.1210/en.2003-1141
    • Pisarska MD, Bae J, Klein C, Hsueh AJ 2004 Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene. Endocrinology 145:3424-3433 (Pubitemid 38830015)
    • (2004) Endocrinology , vol.145 , Issue.7 , pp. 3424-3433
    • Pisarska, M.D.1    Bae, J.2    Klein, C.3    Hsueh, A.J.W.4
  • 10
    • 0028104418 scopus 로고
    • The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)
    • Clark BJ, Wells J, King SR, Stocco DM 1994 The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). J Biol Chem 269:28314-28322
    • (1994) J Biol Chem , vol.269 , pp. 28314-28322
    • Clark, B.J.1    Wells, J.2    King, S.R.3    Stocco, D.M.4
  • 12
    • 0035047848 scopus 로고    scopus 로고
    • StAR protein and the regulation of steroid hormone biosynthesis
    • DOI 10.1146/annurev.physiol.63.1.193
    • Stocco DM 2001 StAR protein and the regulation of steroid hormone biosynthesis. Annu Rev Physiol 63:193-213 (Pubitemid 32304316)
    • (2001) Annual Review of Physiology , vol.63 , pp. 193-213
    • Stocco, D.M.1
  • 13
    • 77952542380 scopus 로고    scopus 로고
    • Human forkhead L2 represses key genes in granulosa cell differentiation including aromatase, P450scc, and cyclin D2
    • Bentsi-Barnes IK, Kuo FT, Barlow GM, Pisarska MD 2010 Human forkhead L2 represses key genes in granulosa cell differentiation including aromatase, P450scc, and cyclin D2. Fertil Steril 94:353-356
    • (2010) Fertil Steril , vol.94 , pp. 353-356
    • Bentsi-Barnes, I.K.1    Kuo, F.T.2    Barlow, G.M.3    Pisarska, M.D.4
  • 14
    • 0036008552 scopus 로고    scopus 로고
    • Exploring the etiology of haploinsufficiency
    • DOI 10.1002/bies.10023
    • Veitia RA 2002 Exploring the etiology of haploinsufficiency. Bioessays 24:175-184 (Pubitemid 34179296)
    • (2002) BioEssays , vol.24 , Issue.2 , pp. 175-184
    • Veitia, R.A.1
  • 15
    • 0026682657 scopus 로고
    • Transcription factors: Structural families and principles of DNA recognition
    • Pabo CO, Sauer RT 1992 Transcription factors: structural families and principles of DNA recognition. Annu Rev Biochem 61:1053-1095
    • (1992) Annu Rev Biochem , vol.61 , pp. 1053-1095
    • Pabo, C.O.1    Sauer, R.T.2
  • 16
    • 0025995844 scopus 로고
    • A structural taxonomy of DNA-binding domains
    • Harrison SC 1991 A structural taxonomy of DNA-binding domains. Nature 353:715-719
    • (1991) Nature , vol.353 , pp. 715-719
    • Harrison, S.C.1
  • 19
    • 67449084841 scopus 로고    scopus 로고
    • Idiosyncratic helix-turn-helix motif in Methanosarcina barkeri seryl-tRNA synthetase has a critical architectural role
    • Bilokapic S, Ivic N, Godinic-Mikulcic V, Piantanida I, Ban N, Weygand-Durasevic I 2009 Idiosyncratic helix-turn-helix motif in Methanosarcina barkeri seryl-tRNA synthetase has a critical architectural role. J Biol Chem 284:10706-10713
    • (2009) J Biol Chem , vol.284 , pp. 10706-10713
    • Bilokapic, S.1    Ivic, N.2    Godinic-Mikulcic, V.3    Piantanida, I.4    Ban, N.5    Weygand-Durasevic, I.6
  • 20
    • 78049503704 scopus 로고    scopus 로고
    • Activin A regulates porcine follicle-stimulating hormone beta-subunit transcription via cooperative actions of SMADs and FOXL2
    • Lamba P, Wang Y, Tran S, Ouspenskaia T, Libasci V, Hébert TE, Miller GJ, Bernard DJ 2010 Activin A regulates porcine follicle-stimulating hormone beta-subunit transcription via cooperative actions of SMADs and FOXL2. Endocrinology 151:5456-5467
    • (2010) Endocrinology , vol.151 , pp. 5456-5467
    • Lamba, P.1    Wang, Y.2    Tran, S.3    Ouspenskaia, T.4    Libasci, V.5    Hébert, T.E.6    Miller, G.J.7    Bernard, D.J.8
  • 21
    • 33644800026 scopus 로고    scopus 로고
    • Structure of the forkhead domain of FOXP2 bound to DNA
    • DOI 10.1016/j.str.2005.10.005, PII S0969212605004338
    • Stroud JC, Wu Y, Bates DL, Han A, Nowick K, Paabo S, Tong H, Chen L 2006 Structure of the forkhead domain of FOXP2 bound to DNA. Structure 14:159-166 (Pubitemid 43350083)
    • (2006) Structure , vol.14 , Issue.1 , pp. 159-166
    • Stroud, J.C.1    Wu, Y.2    Bates, D.L.3    Han, A.4    Nowick, K.5    Paabo, S.6    Tong, H.7    Chen, L.8
  • 22
    • 67649592212 scopus 로고    scopus 로고
    • A novel role for the forkhead transcription factor FOXL2 in activin A-regulated follicle-stimulating hormone beta subunit transcription
    • Lamba P, Fortin J, Tran S, Wang Y, Bernard DJ 2009 A novel role for the forkhead transcription factor FOXL2 in activin A-regulated follicle-stimulating hormone beta subunit transcription. Mol Endocrinol 23:1001-1013
    • (2009) Mol Endocrinol , vol.23 , pp. 1001-1013
    • Lamba, P.1    Fortin, J.2    Tran, S.3    Wang, Y.4    Bernard, D.J.5
  • 25
    • 0027270989 scopus 로고
    • Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5
    • DOI 10.1038/364412a0
    • Clark KL, Halay ED, Lai E, Burley SK 1993 Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 364:412-420 (Pubitemid 23263212)
    • (1993) Nature , vol.364 , Issue.6436 , pp. 412-420
    • Clark, K.L.1    Halay, E.D.2    Lai, E.3    Burley, S.K.4
  • 28
    • 70349783734 scopus 로고    scopus 로고
    • Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene
    • Kuo FT, Bentsi-Barnes IK, Barlow GM, Bae J, Pisarska MD 2009 Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene. Cell Signal 21:1935-1944
    • (2009) Cell Signal , vol.21 , pp. 1935-1944
    • Kuo, F.T.1    Bentsi-Barnes, I.K.2    Barlow, G.M.3    Bae, J.4    Pisarska, M.D.5
  • 30
    • 16344385453 scopus 로고    scopus 로고
    • E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription
    • DOI 10.1038/sj.emboj.7600528
    • Lluís F, Ballestar E, Suelves M, Esteller M, Muñoz- Cánoves P 2005 E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription. EMBO J 24:974-984 (Pubitemid 40470146)
    • (2005) EMBO Journal , vol.24 , Issue.5 , pp. 974-984
    • Lluis, F.1    Ballestar, E.2    Suelves, M.3    Esteller, M.4    Munoz-Canoves, P.5
  • 32
    • 77954839635 scopus 로고    scopus 로고
    • FOXL2 interacts with steroidogenic factor-1 (SF-1) and represses SF-1-induced CYP17 transcription in granulosa cells
    • Park M, Shin E, Won M, Kim JH, Go H, Kim HL, Ko JJ, Lee K, Bae J 2010 FOXL2 interacts with steroidogenic factor-1 (SF-1) and represses SF-1-induced CYP17 transcription in granulosa cells. Mol Endocrinol 24:1024-1036
    • (2010) Mol Endocrinol , vol.24 , pp. 1024-1036
    • Park, M.1    Shin, E.2    Won, M.3    Kim, J.H.4    Go, H.5    Kim, H.L.6    Ko, J.J.7    Lee, K.8    Bae, J.9
  • 33
    • 33847203240 scopus 로고    scopus 로고
    • Foxl2 up-regulates aromatase gene transcription in a female-specific manner by binding to the promoter as well as interacting with ad4 binding protein/steroidogenic factor 1
    • Wang DS, Kobayashi T, Zhou LY, Paul-Prasanth B, Ijiri S, Sakai F, Okubo K, Morohashi K, Nagahama Y 2007 Foxl2 up-regulates aromatase gene transcription in a female-specific manner by binding to the promoter as well as interacting with ad4 binding protein/steroidogenic factor 1. Mol Endocrinol 21:712-725
    • (2007) Mol Endocrinol , vol.21 , pp. 712-725
    • Wang, D.S.1    Kobayashi, T.2    Zhou, L.Y.3    Paul-Prasanth, B.4    Ijiri, S.5    Sakai, F.6    Okubo, K.7    Morohashi, K.8    Nagahama, Y.9
  • 35
    • 84355161774 scopus 로고    scopus 로고
    • Relative expression of genes encoding SMAD signal transduction factors in human granulosa cells is correlated with oocyte quality
    • 16 July 10.1007/s10815-011-9609-6
    • Kuo FT, Fan K, Ambartsumyan G, Menon P, Ketefian A, Bentsi-Barnes IK, Pisarska MD 16 July 2011 Relative expression of genes encoding SMAD signal transduction factors in human granulosa cells is correlated with oocyte quality. J Assist Reprod Genet 10.1007/s10815-011-9609-6
    • (2011) J Assist Reprod Genet
    • Kuo, F.T.1    Fan, K.2    Ambartsumyan, G.3    Menon, P.4    Ketefian, A.5    Bentsi-Barnes, I.K.6    Pisarska, M.D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.