Prostaglandin E 2 release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 38, 2011, Pages 16104-16109

  Clasadonte, Jerome ^a,b   Poulain, Pierre ^a,b   Hanchate, Naresh K ^a,b   Corfas, Gabriel ^c,d   Ojeda, Sergio R ^e   Prevot, Vincent ^a,b  

^a INSERM   (France)

^b UNIV LILLE   (France)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Cyclooxygenase; Fertility; Glia to neuron signaling; Luteinizing hormone releasing hormone; Preoptic region

Indexed keywords

FLUOROACETIC ACID; GONADORELIN; GREEN FLUORESCENT PROTEIN; INDOMETACIN; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E2; BUTAPROST; CYCLIC AMP DEPENDENT PROTEIN KINASE; DRUG DERIVATIVE; ISOQUINOLINE DERIVATIVE; N (2 (4 BROMOCINNAMYLAMINO)ETHYL) 5 ISOQUINOLINESULFONAMIDE; N-(2-(4-BROMOCINNAMYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN E1; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN KINASE INHIBITOR; SULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN SLICE; CELL ACTIVATION; CELL COMMUNICATION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; INTRACELLULAR SIGNALING; MALE; MOUSE; NERVE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; ANIMAL; BRAIN; CELL MEMBRANE POTENTIAL; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; EXCITATORY POSTSYNAPTIC POTENTIAL; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; SECRETION; TRANSGENIC MOUSE;

MUS;

ALPROSTADIL; ANIMALS; ASTROCYTES; BRAIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; GONADOTROPIN-RELEASING HORMONE; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; INDOMETHACIN; ISOQUINOLINES; MALE; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; NEURONS; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE INHIBITORS; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; SULFONAMIDES;

EID: 80053134589     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1107533108     Document Type: Article

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